Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases
It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demo...
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| Materiálatiipa: | Online |
| Giella: | eaŋgalasgiella |
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Frontiers Media SA
2021
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| Fáttát: | |
| Liŋkkat: | 32018 |
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| _version_ | 1869515242718887936 |
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| author | Rory R. Koenen Elena Aikawa |
| author_browse | Elena Aikawa Rory R. Koenen |
| author_facet | Rory R. Koenen Elena Aikawa |
| author_sort | Rory R. Koenen |
| collection | Directory of Open Access Books |
| description | It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demonstrated that extracellular vesicles released from cells serve as a mode of cellular communication. They can carry diverse molecular payload (e.g. nucleic acids, bioactive lipids and proteins) to distal organs and recipient cells. Extracellular vesicles can be classified into three major groups: exosomes, microvesicles, and apoptotic bodies. All these types of extracellular vesicles can be found in a variety of biologic specimen and their numbers, distribution and composition may serve as biomarkers for various disorders, including cardiovascular disease. Although extracellular vesicle-mediated processes are currently best characterized in the fields of cancer biology and neurobiology, evidence is accumulating that extracellular vesicles play a key role in the pathophysiology of diabetes, thrombosis, inflammation and cardiovascular calcification. In this Research Topic, we invited review and methodological articles that advance our understanding of extracellular vesicle-related processes in vascular biology. |
| format | Online |
| id | doab-20.500.12854ir-47258 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-472582024-03-30T23:21:43Z Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases Rory R. Koenen Elena Aikawa R5-920 Angiogenesis Atherosclerosis Extracellular vesicles Calcification Biomarkers Cardiovascular disease Inflammation Exosomes Platelets Heart valve thema EDItEUR::M Medicine and Nursing It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demonstrated that extracellular vesicles released from cells serve as a mode of cellular communication. They can carry diverse molecular payload (e.g. nucleic acids, bioactive lipids and proteins) to distal organs and recipient cells. Extracellular vesicles can be classified into three major groups: exosomes, microvesicles, and apoptotic bodies. All these types of extracellular vesicles can be found in a variety of biologic specimen and their numbers, distribution and composition may serve as biomarkers for various disorders, including cardiovascular disease. Although extracellular vesicle-mediated processes are currently best characterized in the fields of cancer biology and neurobiology, evidence is accumulating that extracellular vesicles play a key role in the pathophysiology of diabetes, thrombosis, inflammation and cardiovascular calcification. In this Research Topic, we invited review and methodological articles that advance our understanding of extracellular vesicle-related processes in vascular biology. 2021-02-11T13:19:33Z 2021-02-11T13:19:33Z 2019-01-23 14:53:43 2018 book 32018 16648714 9782889456208 https://directory.doabooks.org/handle/20.500.12854/47258 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/5398/extracellular-vesicle-mediated-processes-in-cardiovascular-diseases Frontiers Media SA 10.3389/978-2-88945-620-8 10.3389/978-2-88945-620-8 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889456208 118 open access |
| spellingShingle | R5-920 Angiogenesis Atherosclerosis Extracellular vesicles Calcification Biomarkers Cardiovascular disease Inflammation Exosomes Platelets Heart valve thema EDItEUR::M Medicine and Nursing Rory R. Koenen Elena Aikawa Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases |
| title | Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases |
| title_full | Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases |
| title_fullStr | Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases |
| title_full_unstemmed | Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases |
| title_short | Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases |
| title_sort | extracellular vesicle mediated processes in cardiovascular diseases |
| topic | R5-920 Angiogenesis Atherosclerosis Extracellular vesicles Calcification Biomarkers Cardiovascular disease Inflammation Exosomes Platelets Heart valve thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 Angiogenesis Atherosclerosis Extracellular vesicles Calcification Biomarkers Cardiovascular disease Inflammation Exosomes Platelets Heart valve thema EDItEUR::M Medicine and Nursing |
| url | 32018 |
| work_keys_str_mv | AT roryrkoenen extracellularvesiclemediatedprocessesincardiovasculardiseases AT elenaaikawa extracellularvesiclemediatedprocessesincardiovasculardiseases |