Galectins in Cancer and Translational Medicine
In the post-genomic era, many efforts have been devoted to better understanding the biological information encoded by the cell “glycome” in normal and pathologic conditions. The glycan signature of human cells plays a pivotal role in regulating fundamental biological processes, which are critical fo...
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| Formaat: | Online |
| Taal: | Engels |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online toegang: | 29773 |
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| _version_ | 1869524815162900480 |
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| author | Armando Bartolazzi (Ed.) |
| author_browse | Armando Bartolazzi (Ed.) |
| author_facet | Armando Bartolazzi (Ed.) |
| author_sort | Armando Bartolazzi (Ed.) |
| collection | Directory of Open Access Books |
| description | In the post-genomic era, many efforts have been devoted to better understanding the biological information encoded by the cell “glycome” in normal and pathologic conditions. The glycan signature of human cells plays a pivotal role in regulating fundamental biological processes, which are critical for cell physiology and for cancer as well. Galectins (also worded S-type lectins) are an evolutionarily conserved family of endogenous lectins, which bind carbohydrates with high specificity. These molecules, which can be found both intracellularly and in the extracellular milieu, are functionally active in converting glycan-containing information into cell biological programs. This fashionable mechanism of signal transduction plays a relevant role in regulating several biological functions, including RNA splicing, gene transcription, cell migration and differentiation, apoptosis, immune response, and tumor growth and progression. It is not surprising, indeed, that a large number of studies on galectin–glycan interactions and galectins expression and function in human diseases have been published in the recent literature, spanning from immunology to cardiovascular medicine, from diagnostic Pathology to nuclear medicine. The aim of this Special Issue of IJMS is to collect selected contributions in the field reporting data, concepts, and new ideas, which have the potential to be translated in a clinical setting in the near future, in order to improve the diagnosis and treatment of cancer and other relevant human diseases. |
| format | Online |
| id | doab-20.500.12854ir-48261 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-482612024-03-31T13:08:16Z Galectins in Cancer and Translational Medicine Armando Bartolazzi (Ed.) R5-920 QH301-705.5 RM1-950 galectins in therapy galectins and cancer galectins galectin-8 galectin-9 galectins in diagnosis galectins and immunity galectins and human diseases galectin-3 galectin-1 thema EDItEUR::M Medicine and Nursing In the post-genomic era, many efforts have been devoted to better understanding the biological information encoded by the cell “glycome” in normal and pathologic conditions. The glycan signature of human cells plays a pivotal role in regulating fundamental biological processes, which are critical for cell physiology and for cancer as well. Galectins (also worded S-type lectins) are an evolutionarily conserved family of endogenous lectins, which bind carbohydrates with high specificity. These molecules, which can be found both intracellularly and in the extracellular milieu, are functionally active in converting glycan-containing information into cell biological programs. This fashionable mechanism of signal transduction plays a relevant role in regulating several biological functions, including RNA splicing, gene transcription, cell migration and differentiation, apoptosis, immune response, and tumor growth and progression. It is not surprising, indeed, that a large number of studies on galectin–glycan interactions and galectins expression and function in human diseases have been published in the recent literature, spanning from immunology to cardiovascular medicine, from diagnostic Pathology to nuclear medicine. The aim of this Special Issue of IJMS is to collect selected contributions in the field reporting data, concepts, and new ideas, which have the potential to be translated in a clinical setting in the near future, in order to improve the diagnosis and treatment of cancer and other relevant human diseases. 2021-02-11T14:15:34Z 2021-02-11T14:15:34Z 2018-12-12 12:21:34 2018 book 29773 9783038974093 9783038974086 https://directory.doabooks.org/handle/20.500.12854/48261 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://play.google.com/books/publish/a/14935057684283403269#details/ISBN:9783038974086 https://www.mdpi.com/books/pdfview/book/1046 https://www.mdpi.com/books/pdfview/book/1046 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-409-3 10.3390/books978-3-03897-409-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038974093 9783038974086 350 open access |
| spellingShingle | R5-920 QH301-705.5 RM1-950 galectins in therapy galectins and cancer galectins galectin-8 galectin-9 galectins in diagnosis galectins and immunity galectins and human diseases galectin-3 galectin-1 thema EDItEUR::M Medicine and Nursing Armando Bartolazzi (Ed.) Galectins in Cancer and Translational Medicine |
| title | Galectins in Cancer and Translational Medicine |
| title_full | Galectins in Cancer and Translational Medicine |
| title_fullStr | Galectins in Cancer and Translational Medicine |
| title_full_unstemmed | Galectins in Cancer and Translational Medicine |
| title_short | Galectins in Cancer and Translational Medicine |
| title_sort | galectins in cancer and translational medicine |
| topic | R5-920 QH301-705.5 RM1-950 galectins in therapy galectins and cancer galectins galectin-8 galectin-9 galectins in diagnosis galectins and immunity galectins and human diseases galectin-3 galectin-1 thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 QH301-705.5 RM1-950 galectins in therapy galectins and cancer galectins galectin-8 galectin-9 galectins in diagnosis galectins and immunity galectins and human diseases galectin-3 galectin-1 thema EDItEUR::M Medicine and Nursing |
| url | 29773 |
| work_keys_str_mv | AT armandobartolazzied galectinsincancerandtranslationalmedicine |