Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise
From an evolutionary perspective, our species has relied upon physical activity for most of its history to survive and has had to escape from predators, to scavenge for food, and to use physique to work or build necessary means for everyday life. Physical activity has been part of our evolution and...
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| Формат: | Online |
| Мова: | Англійська |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Онлайн доступ: | 46066 |
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| _version_ | 1869529058397650944 |
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| author | Di Liegro, Italia |
| author_browse | Di Liegro, Italia |
| author_facet | Di Liegro, Italia |
| author_sort | Di Liegro, Italia |
| collection | Directory of Open Access Books |
| description | From an evolutionary perspective, our species has relied upon physical activity for most of its history to survive and has had to escape from predators, to scavenge for food, and to use physique to work or build necessary means for everyday life. Physical activity has been part of our evolution and progress since the very beginning and, consequently, our entire body has been programmed to be active physically. In the last 20 years, scientific research has increasingly shown that our ancient survival principle has beneficial effects not only on the cells and organs involved in physical activities but on the metabolism of the entire organism, influencing the homeostasis and integration of all bodily functions, likely stimulating the production of hormones and other regulatory molecules, with each affecting vital signalling pathways. Most of the web of factors involved in molecular signalling upon exercise are suspected to be centrally controlled by the brain, which has been reported to be deeply modified by physical activity. Such complexity requires a multifaceted approach to shed light on the molecular interactions that occur between physical activity and its outcome at a cellular level. |
| format | Online |
| id | doab-20.500.12854ir-48390 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-483902024-04-05T12:35:12Z Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise Di Liegro, Italia QH426-470 QH301-705.5 Q1-390 TFRC single nucleotide polymorphism high-density lipoprotein blood cell counts epigenetics intestinal microbiome iron metabolism Irisin exercise and health healthy lifestyle physical exercise single nucleotide polymorphisms Taiwan biobank obesity glucokinase-regulator ?-actinin body mass index hepatic lipase Taiwan Biobank genotyping myokines DNA-methylation NK brain health gene expression ferritin exercise and aging exercise endurance antihypertensive therapy genetics gut microbiome ketogenic diet inflammation PCBP1 PCBP2 marathon runners natural killer cell behavior aerobic exercise exercise and neurodegeneration BDNF gut microbiota physical activity performance lactate sport ketogenic diet and fat body fat thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) From an evolutionary perspective, our species has relied upon physical activity for most of its history to survive and has had to escape from predators, to scavenge for food, and to use physique to work or build necessary means for everyday life. Physical activity has been part of our evolution and progress since the very beginning and, consequently, our entire body has been programmed to be active physically. In the last 20 years, scientific research has increasingly shown that our ancient survival principle has beneficial effects not only on the cells and organs involved in physical activities but on the metabolism of the entire organism, influencing the homeostasis and integration of all bodily functions, likely stimulating the production of hormones and other regulatory molecules, with each affecting vital signalling pathways. Most of the web of factors involved in molecular signalling upon exercise are suspected to be centrally controlled by the brain, which has been reported to be deeply modified by physical activity. Such complexity requires a multifaceted approach to shed light on the molecular interactions that occur between physical activity and its outcome at a cellular level. 2021-02-11T14:23:20Z 2021-02-11T14:23:20Z 2020-06-09 16:38:57 2020 book 46066 9783039284801 9783039284818 https://directory.doabooks.org/handle/20.500.12854/48390 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/2259 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03928-481-8 10.3390/books978-3-03928-481-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039284801 9783039284818 170 open access |
| spellingShingle | QH426-470 QH301-705.5 Q1-390 TFRC single nucleotide polymorphism high-density lipoprotein blood cell counts epigenetics intestinal microbiome iron metabolism Irisin exercise and health healthy lifestyle physical exercise single nucleotide polymorphisms Taiwan biobank obesity glucokinase-regulator ?-actinin body mass index hepatic lipase Taiwan Biobank genotyping myokines DNA-methylation NK brain health gene expression ferritin exercise and aging exercise endurance antihypertensive therapy genetics gut microbiome ketogenic diet inflammation PCBP1 PCBP2 marathon runners natural killer cell behavior aerobic exercise exercise and neurodegeneration BDNF gut microbiota physical activity performance lactate sport ketogenic diet and fat body fat thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) Di Liegro, Italia Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise |
| title | Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise |
| title_full | Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise |
| title_fullStr | Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise |
| title_full_unstemmed | Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise |
| title_short | Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise |
| title_sort | genetic and epigenetic modulation of cell functions by physical exercise |
| topic | QH426-470 QH301-705.5 Q1-390 TFRC single nucleotide polymorphism high-density lipoprotein blood cell counts epigenetics intestinal microbiome iron metabolism Irisin exercise and health healthy lifestyle physical exercise single nucleotide polymorphisms Taiwan biobank obesity glucokinase-regulator ?-actinin body mass index hepatic lipase Taiwan Biobank genotyping myokines DNA-methylation NK brain health gene expression ferritin exercise and aging exercise endurance antihypertensive therapy genetics gut microbiome ketogenic diet inflammation PCBP1 PCBP2 marathon runners natural killer cell behavior aerobic exercise exercise and neurodegeneration BDNF gut microbiota physical activity performance lactate sport ketogenic diet and fat body fat thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) |
| topic_facet | QH426-470 QH301-705.5 Q1-390 TFRC single nucleotide polymorphism high-density lipoprotein blood cell counts epigenetics intestinal microbiome iron metabolism Irisin exercise and health healthy lifestyle physical exercise single nucleotide polymorphisms Taiwan biobank obesity glucokinase-regulator ?-actinin body mass index hepatic lipase Taiwan Biobank genotyping myokines DNA-methylation NK brain health gene expression ferritin exercise and aging exercise endurance antihypertensive therapy genetics gut microbiome ketogenic diet inflammation PCBP1 PCBP2 marathon runners natural killer cell behavior aerobic exercise exercise and neurodegeneration BDNF gut microbiota physical activity performance lactate sport ketogenic diet and fat body fat thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) |
| url | 46066 |
| work_keys_str_mv | AT diliegroitalia geneticandepigeneticmodulationofcellfunctionsbyphysicalexercise |