Good News - Bad News: The Two Faces of Immune Privilege
Immune privilege was once thought to be the property of a few select sites that include the eye, brain, testis, pregnant uterus and (of all things) the hamster cheek pouch, and was believed to be mainly based on sequestration behind blood-tissue barriers. This view has changed. Immune privilege is n...
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| Main Authors: | , |
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| Formato: | Online |
| Idioma: | inglés |
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Frontiers Media SA
2021
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| Acceso en liña: | 18663 |
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| _version_ | 1869517116054437888 |
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| author | Joan Stein-Streilein Rachel R Caspi |
| author_browse | Joan Stein-Streilein Rachel R Caspi |
| author_facet | Joan Stein-Streilein Rachel R Caspi |
| author_sort | Joan Stein-Streilein |
| collection | Directory of Open Access Books |
| description | Immune privilege was once thought to be the property of a few select sites that include the eye, brain, testis, pregnant uterus and (of all things) the hamster cheek pouch, and was believed to be mainly based on sequestration behind blood-tissue barriers. This view has changed. Immune privilege is now considered to constitute a more general phenomenon through which tissues are able to actively direct and control immune responses taking place in their “territory” to preserve their structural and functional integrity in the face of inflammatory processes. These positive aspects of immune privilege can be hijacked by tumors to their survival advantage and to the detriment of the host. This Research Topic dissects the beneficial and deleterious consequences of immune privilege in terms of the cellular and molecular mechanisms that various tissues and tumors use, each in its own fashion, to regulate immune processes that affect them, at the local and the systemic level. |
| format | Online |
| id | doab-20.500.12854ir-48751 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-487512024-03-30T23:22:01Z Good News - Bad News: The Two Faces of Immune Privilege Joan Stein-Streilein Rachel R Caspi R5-920 RC581-607 Eye Immune Privilege immune suppression tolerance regulatory cells thema EDItEUR::M Medicine and Nursing Immune privilege was once thought to be the property of a few select sites that include the eye, brain, testis, pregnant uterus and (of all things) the hamster cheek pouch, and was believed to be mainly based on sequestration behind blood-tissue barriers. This view has changed. Immune privilege is now considered to constitute a more general phenomenon through which tissues are able to actively direct and control immune responses taking place in their “territory” to preserve their structural and functional integrity in the face of inflammatory processes. These positive aspects of immune privilege can be hijacked by tumors to their survival advantage and to the detriment of the host. This Research Topic dissects the beneficial and deleterious consequences of immune privilege in terms of the cellular and molecular mechanisms that various tissues and tumors use, each in its own fashion, to regulate immune processes that affect them, at the local and the systemic level. 2021-02-11T14:44:31Z 2021-02-11T14:44:31Z 2016-03-10 08:14:32 2014 book 18663 16648714 9782889193318 https://directory.doabooks.org/handle/20.500.12854/48751 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Good_News_-_Bad_News_The_Two_Faces_of_Immune_Privilege/368 http://journal.frontiersin.org/researchtopic/377/good-news---bad-news-the-two-faces-of-immune-privilege Frontiers Media SA 10.3389/978-2-88919-331-8 10.3389/978-2-88919-331-8 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193318 109 open access |
| spellingShingle | R5-920 RC581-607 Eye Immune Privilege immune suppression tolerance regulatory cells thema EDItEUR::M Medicine and Nursing Joan Stein-Streilein Rachel R Caspi Good News - Bad News: The Two Faces of Immune Privilege |
| title | Good News - Bad News: The Two Faces of Immune Privilege |
| title_full | Good News - Bad News: The Two Faces of Immune Privilege |
| title_fullStr | Good News - Bad News: The Two Faces of Immune Privilege |
| title_full_unstemmed | Good News - Bad News: The Two Faces of Immune Privilege |
| title_short | Good News - Bad News: The Two Faces of Immune Privilege |
| title_sort | good news bad news the two faces of immune privilege |
| topic | R5-920 RC581-607 Eye Immune Privilege immune suppression tolerance regulatory cells thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RC581-607 Eye Immune Privilege immune suppression tolerance regulatory cells thema EDItEUR::M Medicine and Nursing |
| url | 18663 |
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