The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life

Bacteria are among the earliest forms of life on Earth. Notwithstanding their small size and primitive origin, bacteria still have a tremendous impact on everyday human life. Over the centuries, research into bacteria have provided and enriched the fundamental biological knowledge due to their readi...

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Ngā kaituhi matua: Manuel Espinosa, Tatiana Venkova, Chew Chieng Yeo
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I whakaputaina: Frontiers Media SA 2021
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author Manuel Espinosa
Tatiana Venkova
Chew Chieng Yeo
author_browse Chew Chieng Yeo
Manuel Espinosa
Tatiana Venkova
author_facet Manuel Espinosa
Tatiana Venkova
Chew Chieng Yeo
author_sort Manuel Espinosa
collection Directory of Open Access Books
description Bacteria are among the earliest forms of life on Earth. Notwithstanding their small size and primitive origin, bacteria still have a tremendous impact on everyday human life. Over the centuries, research into bacteria have provided and enriched the fundamental biological knowledge due to their readily measured processes and effects on higher organisms. Although molecular genetics and microbiology were among the scientific fields that have mostly benefited from the discoveries made in bacteria, our current state of knowledge has gone beyond what anyone could have ever imagined. The present Research Topic aims to cover new and exciting broad aspects of the importance of bacteria to human life, both positive and negative influences. Regulation of bacterial gene expression, replication and segregation control mechanisms, cell to cell communication via quorum sensors, and the relatively recent finding of bacterial immunity via CRISPR, have led to the development of many, and very important new tools in biotechnology and the emerging field of molecular medicine. The battle against infectious diseases has also benefited from the genetic approaches that have been developed in the quest for finding new targets and novel drugs against pathogenic bacteria. At the next level, the human microbiome project has opened up new avenues in understanding the role of bacteria in human health and wellbeing. Finally, the relationship between bacterial infections and human cancers will also be covered, a subject that is still under verification through rigorous experimental approaches. Special emphasis will be given to the bacterial accessory genome, i.e the mobilome, as the primary cause of health-threatening antimicrobial resistance and the production of toxins and virulence factors. Taking into account the evolutionary importance of horizontal gene transfer and the additional beneficial roles of certain bacterial mobile genetic elements, they help project best “the Good, the Bad and the Ugly” outline of this topic. At the time this eBook is about to be published, our Research Topic has registered nearly 55, 000 views.
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spelling doab-20.500.12854ir-487532024-04-05T17:31:00Z The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life Manuel Espinosa Tatiana Venkova Chew Chieng Yeo QR1-502 Q1-390 bacteria and cancer virulence antimicrobial resistance infectious diseases horizontal gene spread mobile genetic elements bacterial immunity thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) Bacteria are among the earliest forms of life on Earth. Notwithstanding their small size and primitive origin, bacteria still have a tremendous impact on everyday human life. Over the centuries, research into bacteria have provided and enriched the fundamental biological knowledge due to their readily measured processes and effects on higher organisms. Although molecular genetics and microbiology were among the scientific fields that have mostly benefited from the discoveries made in bacteria, our current state of knowledge has gone beyond what anyone could have ever imagined. The present Research Topic aims to cover new and exciting broad aspects of the importance of bacteria to human life, both positive and negative influences. Regulation of bacterial gene expression, replication and segregation control mechanisms, cell to cell communication via quorum sensors, and the relatively recent finding of bacterial immunity via CRISPR, have led to the development of many, and very important new tools in biotechnology and the emerging field of molecular medicine. The battle against infectious diseases has also benefited from the genetic approaches that have been developed in the quest for finding new targets and novel drugs against pathogenic bacteria. At the next level, the human microbiome project has opened up new avenues in understanding the role of bacteria in human health and wellbeing. Finally, the relationship between bacterial infections and human cancers will also be covered, a subject that is still under verification through rigorous experimental approaches. Special emphasis will be given to the bacterial accessory genome, i.e the mobilome, as the primary cause of health-threatening antimicrobial resistance and the production of toxins and virulence factors. Taking into account the evolutionary importance of horizontal gene transfer and the additional beneficial roles of certain bacterial mobile genetic elements, they help project best “the Good, the Bad and the Ugly” outline of this topic. At the time this eBook is about to be published, our Research Topic has registered nearly 55, 000 views. 2021-02-11T14:44:37Z 2021-02-11T14:44:37Z 2019-01-23 14:53:43 2018 book 31984 16648714 9782889455744 https://directory.doabooks.org/handle/20.500.12854/48753 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/5409/the-good-the-bad-and-the-ugly-multiple-roles-of-bacteria-in-human-life Frontiers Media SA 10.3389/978-2-88945-574-4 10.3389/978-2-88945-574-4 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889455744 518 open access
spellingShingle QR1-502
Q1-390
bacteria and cancer
virulence
antimicrobial resistance
infectious diseases
horizontal gene spread
mobile genetic elements
bacterial immunity
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
Manuel Espinosa
Tatiana Venkova
Chew Chieng Yeo
The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life
title The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life
title_full The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life
title_fullStr The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life
title_full_unstemmed The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life
title_short The Good, The Bad and The Ugly: Multiple Roles of Bacteria in Human Life
title_sort good the bad and the ugly multiple roles of bacteria in human life
topic QR1-502
Q1-390
bacteria and cancer
virulence
antimicrobial resistance
infectious diseases
horizontal gene spread
mobile genetic elements
bacterial immunity
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
topic_facet QR1-502
Q1-390
bacteria and cancer
virulence
antimicrobial resistance
infectious diseases
horizontal gene spread
mobile genetic elements
bacterial immunity
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
url 31984
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