Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America

Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording imp...

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Main Authors: Adolfo M. García, Lucas Sedeño, Robert M.J. Deacon, Patricia Cogram, Agustin Ibáñez
Format: Online
Language:English
Published: Frontiers Media SA 2021
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Online Access:31905
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author Adolfo M. García
Lucas Sedeño
Robert M.J. Deacon
Patricia Cogram
Agustin Ibáñez
author_browse Adolfo M. García
Agustin Ibáñez
Lucas Sedeño
Patricia Cogram
Robert M.J. Deacon
author_facet Adolfo M. García
Lucas Sedeño
Robert M.J. Deacon
Patricia Cogram
Agustin Ibáñez
author_sort Adolfo M. García
collection Directory of Open Access Books
description Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.
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publishDate 2021
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spelling doab-20.500.12854ir-496202024-04-05T12:36:04Z Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America Adolfo M. García Lucas Sedeño Robert M.J. Deacon Patricia Cogram Agustin Ibáñez RC321-571 Q1-390 South America Multicenter research Neurodegenerative Diseases Neurosciences Public Health Animals Clinical Protocols Research Human Experimentation Dementia thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America. 2021-02-11T15:37:01Z 2021-02-11T15:37:01Z 2019-01-23 14:53:42 2018 book 31905 16648714 9782889454945 https://directory.doabooks.org/handle/20.500.12854/49620 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/4457/human-and-animal-models-for-translational-research-on-neurodegeneration-challenges-and-opportunities Frontiers Media SA 10.3389/978-2-88945-494-5 10.3389/978-2-88945-494-5 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889454945 217 open access
spellingShingle RC321-571
Q1-390
South America
Multicenter research
Neurodegenerative Diseases
Neurosciences
Public Health
Animals
Clinical Protocols
Research
Human Experimentation
Dementia
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Adolfo M. García
Lucas Sedeño
Robert M.J. Deacon
Patricia Cogram
Agustin Ibáñez
Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
title Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
title_full Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
title_fullStr Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
title_full_unstemmed Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
title_short Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
title_sort human and animal models for translational research on neurodegeneration challenges and opportunities from south america
topic RC321-571
Q1-390
South America
Multicenter research
Neurodegenerative Diseases
Neurosciences
Public Health
Animals
Clinical Protocols
Research
Human Experimentation
Dementia
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet RC321-571
Q1-390
South America
Multicenter research
Neurodegenerative Diseases
Neurosciences
Public Health
Animals
Clinical Protocols
Research
Human Experimentation
Dementia
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url 31905
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