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Hurdles for Phage Therapy (PT) to Become a Reality

Alternative treatment modes for antibiotic-resistant bacterial pathogens have become a public health priority. Bacteriophages are bacterial viruses that infect and lyse bacterial cells. Since bacteriophages are frequently bacterial host species-specific and can often also infect antibiotic-resistant...

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Gardado en:
Autor Principal: Brüssow, Harald
Formato: Online
Idioma:inglés
Publicado: MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
QH301-705.5
QR1-502
Q1-390
alginate
abortive infection
n/a
bacterial resistance
bacteriophages
ATMP
MALDI-MS
adaptation
Bacteriophage
horizontal gene transfer
adaptive immunity
co-evolution
Listeria ivanovii
personalised medicines
pH stability
phage-human host interaction
vB_SauM-fRuSau02
antimicrobial resistance
phagodisinfection
biofilm
capsule depolymerase
animal model
phage cocktails
Enterococcus
cases report
zoonosis
resistance
magistral formula
experimental therapy
Belgium
phage therapy
E. faecalis
nontraditional antibacterial
industrial phage application
Democratic Republic of the Congo
OrthoMCL
Germany
high-throughput sequencing
antimicrobial
infection
antibiotic therapy
Kayvirus
phages
Twortlikevirus
bacterial disease
human host
Pseudomonas aeruginosa
phage
multidrug-resistant bacteria
bacterial infection
Salmonella Typhi
rhamnopolysaccharide
compassionate use
crop production
compounding pharmacy
antimicrobial resistance (AMR)
best practices
bacteriophage efficacy
phage sensitivity
antibiotic-resistance
antibiotic
lysins
PTMP
Escherichia coli
typhoid fever
patent landscape
phage preparation
innate immunity
anti-phage antibodies
immunology
Staphylococcus aureus
global health
clinical trial
adsorption
Brussels
phage-resistance
Galleria mellonella
science communication
history of science
virus–host interactions
foodborne illness
prophage
resistance management
biofilms
IND
immunomodulation
frequency of resistance
capsule
gastrointestinal tract
phage-host interactions
disinfection
production
bacteriophage therapy
bacteriophage
Staphylococcus
magistral preparation
extended-spectrum beta lactamases (ESBL)
Viral proteins
antibiotic resistance
genomics
phage biocontrol
therapy
target selection
viral genomes
evolution
pharmaceutical paradigm shift
personalized medicine
pharmaceutical legislation
food safety
regulation
virulence
developing countries
infectious disease
regulatory framework
sustainable agriculture
Klebsiella pneumoniae
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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