The Identification of the Genetic Components of Autism Spectrum Disorders 2017
This textbook is dedicated to the study of genetic factors contributing to autism and includes a collection of original research and review articles related to this topic. Autism spectrum disorders (ASD) include a collection of neurodevelopmental disorders characterized by three recognized behaviora...
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| Natura: | Online |
| Lingua: | inglese |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Accesso online: | 24204 |
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| _version_ | 1869519476694712320 |
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| author | Merlin G. Butler (Ed.) |
| author_browse | Merlin G. Butler (Ed.) |
| author_facet | Merlin G. Butler (Ed.) |
| author_sort | Merlin G. Butler (Ed.) |
| collection | Directory of Open Access Books |
| description | This textbook is dedicated to the study of genetic factors contributing to autism and includes a collection of original research and review articles related to this topic. Autism spectrum disorders (ASD) include a collection of neurodevelopmental disorders characterized by three recognized behavioral domains involving difficulties in communication, social interaction and repetitive behavior. ASD affects 1 to 2 percent of children and is on the increase worldwide. Significant genetic contributions and mechanisms underlie the causation of ASD. Advances in genetic technology and better awareness have led to a diagnosis of 50 to 70 percent of individuals with ASD primarily due to chromosomal abnormalities, submicroscopic deletions or duplications now identified with high-resolution microarray analysis, next-generation DNA (exome) sequencing of gene variants or mutations, recognized single gene disorders or metabolic disturbances. Through discovery by searching genomic databases and peer-reviewed research articles, nearly 800 genes have been identified to contribute to ASD. Highlights in the field of autism research, discovery and identification of genetic components with characterization will be addressed. Furthermore, reviews of current understanding of the causes and diagnostic approaches for ASD and related syndromes will be presented along with discussion of psychiatric/behavior comorbidities and related features, environmental risk factors, parental attitudes and treatment. |
| format | Online |
| id | doab-20.500.12854ir-49817 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-498172024-04-05T12:32:22Z The Identification of the Genetic Components of Autism Spectrum Disorders 2017 Merlin G. Butler (Ed.) QH301-705.5 genetic treatment genes biomarkers copy number variants and mutations genetic factors next generation DNA exome sequencing and functional analysis autism and autism spectrum disorders causation and etiology reviews neurodevelopment and physiology testing syndromes environmental risk factors thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This textbook is dedicated to the study of genetic factors contributing to autism and includes a collection of original research and review articles related to this topic. Autism spectrum disorders (ASD) include a collection of neurodevelopmental disorders characterized by three recognized behavioral domains involving difficulties in communication, social interaction and repetitive behavior. ASD affects 1 to 2 percent of children and is on the increase worldwide. Significant genetic contributions and mechanisms underlie the causation of ASD. Advances in genetic technology and better awareness have led to a diagnosis of 50 to 70 percent of individuals with ASD primarily due to chromosomal abnormalities, submicroscopic deletions or duplications now identified with high-resolution microarray analysis, next-generation DNA (exome) sequencing of gene variants or mutations, recognized single gene disorders or metabolic disturbances. Through discovery by searching genomic databases and peer-reviewed research articles, nearly 800 genes have been identified to contribute to ASD. Highlights in the field of autism research, discovery and identification of genetic components with characterization will be addressed. Furthermore, reviews of current understanding of the causes and diagnostic approaches for ASD and related syndromes will be presented along with discussion of psychiatric/behavior comorbidities and related features, environmental risk factors, parental attitudes and treatment. 2021-02-11T15:48:01Z 2021-02-11T15:48:01Z 2017-10-27 12:54:46 2017 book 24204 9783038425212 9783038425205 https://directory.doabooks.org/handle/20.500.12854/49817 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://sci.fo/3ym http://www.mdpi.com/books/pdfview/book/374 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038425212 9783038425205 X, 462 open access |
| spellingShingle | QH301-705.5 genetic treatment genes biomarkers copy number variants and mutations genetic factors next generation DNA exome sequencing and functional analysis autism and autism spectrum disorders causation and etiology reviews neurodevelopment and physiology testing syndromes environmental risk factors thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Merlin G. Butler (Ed.) The Identification of the Genetic Components of Autism Spectrum Disorders 2017 |
| title | The Identification of the Genetic Components of Autism Spectrum Disorders 2017 |
| title_full | The Identification of the Genetic Components of Autism Spectrum Disorders 2017 |
| title_fullStr | The Identification of the Genetic Components of Autism Spectrum Disorders 2017 |
| title_full_unstemmed | The Identification of the Genetic Components of Autism Spectrum Disorders 2017 |
| title_short | The Identification of the Genetic Components of Autism Spectrum Disorders 2017 |
| title_sort | identification of the genetic components of autism spectrum disorders 2017 |
| topic | QH301-705.5 genetic treatment genes biomarkers copy number variants and mutations genetic factors next generation DNA exome sequencing and functional analysis autism and autism spectrum disorders causation and etiology reviews neurodevelopment and physiology testing syndromes environmental risk factors thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 genetic treatment genes biomarkers copy number variants and mutations genetic factors next generation DNA exome sequencing and functional analysis autism and autism spectrum disorders causation and etiology reviews neurodevelopment and physiology testing syndromes environmental risk factors thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 24204 |
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