Imaging and monitoring astrocytes in health and disease
Astrocytes are key cellular partners to neurons in the brain. They play an important role in multiple processes such as neurotransmitter recycling, trophic support, antioxidant defense, ionic homeostasis, inflammatory modulation, neurovascular and neurometabolic coupling, neurogenesis, synapse forma...
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| Κύριοι συγγραφείς: | , |
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| Μορφή: | Online |
| Γλώσσα: | Αγγλικά |
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Frontiers Media SA
2021
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| Θέματα: | |
| Διαθέσιμο Online: | 17763 |
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| _version_ | 1869522223570616320 |
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| author | Carole Escartin Keith Murai |
| author_browse | Carole Escartin Keith Murai |
| author_facet | Carole Escartin Keith Murai |
| author_sort | Carole Escartin |
| collection | Directory of Open Access Books |
| description | Astrocytes are key cellular partners to neurons in the brain. They play an important role in multiple processes such as neurotransmitter recycling, trophic support, antioxidant defense, ionic homeostasis, inflammatory modulation, neurovascular and neurometabolic coupling, neurogenesis, synapse formation and synaptic plasticity. In addition to their crucial involvement in normal brain physiology, it is well known that astrocytes adopt a reactive phenotype under most acute and chronic pathological conditions such as ischemia, trauma, brain cancer, epilepsy, demyelinating and neurodegenerative diseases. However, the functional impact of astrocyte reactivity is still unclear. During the last decades, the development of innovative approaches to study astrocytes has significantly improved our understanding of their prominent role in brain function and their contribution to disease states. In particular, new genetic tools, molecular probes, and imaging techniques that achieve high spatial and temporal resolution have revealed new insight into astrocyte functions in situ. This Research Topic provides a collection of cutting-edge techniques, approaches and models to study astrocytes in health and disease. It also suggests new directions to achieve discoveries on these fascinating cells. |
| format | Online |
| id | doab-20.500.12854ir-49952 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-499522024-04-05T12:36:22Z Imaging and monitoring astrocytes in health and disease Carole Escartin Keith Murai RC321-571 Q1-390 brain imaging transgenesis high-resolution imaging gene transfer Reactive astrocytes Electrophysiology neuron-astrocyte interactions In vivo analysis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Astrocytes are key cellular partners to neurons in the brain. They play an important role in multiple processes such as neurotransmitter recycling, trophic support, antioxidant defense, ionic homeostasis, inflammatory modulation, neurovascular and neurometabolic coupling, neurogenesis, synapse formation and synaptic plasticity. In addition to their crucial involvement in normal brain physiology, it is well known that astrocytes adopt a reactive phenotype under most acute and chronic pathological conditions such as ischemia, trauma, brain cancer, epilepsy, demyelinating and neurodegenerative diseases. However, the functional impact of astrocyte reactivity is still unclear. During the last decades, the development of innovative approaches to study astrocytes has significantly improved our understanding of their prominent role in brain function and their contribution to disease states. In particular, new genetic tools, molecular probes, and imaging techniques that achieve high spatial and temporal resolution have revealed new insight into astrocyte functions in situ. This Research Topic provides a collection of cutting-edge techniques, approaches and models to study astrocytes in health and disease. It also suggests new directions to achieve discoveries on these fascinating cells. 2021-02-11T15:55:10Z 2021-02-11T15:55:10Z 2015-12-03 13:02:24 2014 book 17763 16648714 9782889193936 https://directory.doabooks.org/handle/20.500.12854/49952 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Imaging_and_monitoring_astrocytes_in_health_and_disease/374 http://journal.frontiersin.org/researchtopic/1056/imaging-and-monitoring-astrocytes-in-health-and-disease Frontiers Media SA 10.3389/978-2-88919-393-6 10.3389/978-2-88919-393-6 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193936 189 open access |
| spellingShingle | RC321-571 Q1-390 brain imaging transgenesis high-resolution imaging gene transfer Reactive astrocytes Electrophysiology neuron-astrocyte interactions In vivo analysis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Carole Escartin Keith Murai Imaging and monitoring astrocytes in health and disease |
| title | Imaging and monitoring astrocytes in health and disease |
| title_full | Imaging and monitoring astrocytes in health and disease |
| title_fullStr | Imaging and monitoring astrocytes in health and disease |
| title_full_unstemmed | Imaging and monitoring astrocytes in health and disease |
| title_short | Imaging and monitoring astrocytes in health and disease |
| title_sort | imaging and monitoring astrocytes in health and disease |
| topic | RC321-571 Q1-390 brain imaging transgenesis high-resolution imaging gene transfer Reactive astrocytes Electrophysiology neuron-astrocyte interactions In vivo analysis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | RC321-571 Q1-390 brain imaging transgenesis high-resolution imaging gene transfer Reactive astrocytes Electrophysiology neuron-astrocyte interactions In vivo analysis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | 17763 |
| work_keys_str_mv | AT caroleescartin imagingandmonitoringastrocytesinhealthanddisease AT keithmurai imagingandmonitoringastrocytesinhealthanddisease |