Immune System Modeling and Analysis
The rapid development of new methods for immunological data collection - from multicolor flow cytometry, through single-cell imaging, to deep sequencing - presents us now, for the first time, with the ability to analyze and compare large amounts of immunological data in health, aging and disease. Th...
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| Materiálatiipa: | Online |
| Giella: | eaŋgalasgiella |
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Frontiers Media SA
2021
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| Fáttát: | |
| Liŋkkat: | 17736 |
| Fáddágilkorat: |
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| _version_ | 1869520744582479872 |
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| author | Carmen Molina-Paris Ramit Mehr Miles Davenport Rob J. De Boer Veronika Zarnitsyna Michal Or-Guil |
| author_browse | Carmen Molina-Paris Michal Or-Guil Miles Davenport Ramit Mehr Rob J. De Boer Veronika Zarnitsyna |
| author_facet | Carmen Molina-Paris Ramit Mehr Miles Davenport Rob J. De Boer Veronika Zarnitsyna Michal Or-Guil |
| author_sort | Carmen Molina-Paris |
| collection | Directory of Open Access Books |
| description | The rapid development of new methods for immunological data collection - from multicolor flow cytometry, through single-cell imaging, to deep sequencing - presents us now, for the first time, with the ability to analyze and compare large amounts of immunological data in health, aging and disease. The exponential growth of these datasets, however, challenges the theoretical immunology community to develop methods for data organization and analysis. Furthermore, the need to test hypotheses regarding immune function, and generate predictions regarding the outcomes of medical interventions, necessitates the development of mathematical and computational models covering processes on multiple scales, from the genetic and molecular to the cellular and system scales. The last few decades have seen the development of methods for presentation and analysis of clonal repertoires (those of T and B lymphocytes) and phenotypic (surface-marker based) repertoires of all lymphocyte types, and for modeling the intricate network of molecular and cellular interactions within the immune systems. This e-Book, which has first appeared as a ‘Frontiers in Immunology’ research topic, provides a comprehensive, online, open access snapshot of the current state of the art on immune system modeling and analysis. |
| format | Online |
| id | doab-20.500.12854ir-49981 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-499812024-03-30T23:22:44Z Immune System Modeling and Analysis Carmen Molina-Paris Ramit Mehr Miles Davenport Rob J. De Boer Veronika Zarnitsyna Michal Or-Guil R5-920 RC581-607 Immune cell differentiation Immune cell population dynamics and turnover Immunological diseases activation and signaling mathematical modeling immunomics Immune cell receptors lymphocyte repertoires Immune cell migration and immune tissue organization Immune responses to pathogens high-throughput sequencing thema EDItEUR::M Medicine and Nursing The rapid development of new methods for immunological data collection - from multicolor flow cytometry, through single-cell imaging, to deep sequencing - presents us now, for the first time, with the ability to analyze and compare large amounts of immunological data in health, aging and disease. The exponential growth of these datasets, however, challenges the theoretical immunology community to develop methods for data organization and analysis. Furthermore, the need to test hypotheses regarding immune function, and generate predictions regarding the outcomes of medical interventions, necessitates the development of mathematical and computational models covering processes on multiple scales, from the genetic and molecular to the cellular and system scales. The last few decades have seen the development of methods for presentation and analysis of clonal repertoires (those of T and B lymphocytes) and phenotypic (surface-marker based) repertoires of all lymphocyte types, and for modeling the intricate network of molecular and cellular interactions within the immune systems. This e-Book, which has first appeared as a ‘Frontiers in Immunology’ research topic, provides a comprehensive, online, open access snapshot of the current state of the art on immune system modeling and analysis. 2021-02-11T15:56:32Z 2021-02-11T15:56:32Z 2015-12-03 13:02:24 2015 book 17736 16648714 9782889195015 https://directory.doabooks.org/handle/20.500.12854/49981 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Immune_system_modeling_and_analysis/507#nogo http://journal.frontiersin.org/researchtopic/1844/immune-system-modeling-and-analysis Frontiers Media SA 10.3389/978-2-88919-501-5 10.3389/978-2-88919-501-5 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889195015 401 open access |
| spellingShingle | R5-920 RC581-607 Immune cell differentiation Immune cell population dynamics and turnover Immunological diseases activation and signaling mathematical modeling immunomics Immune cell receptors lymphocyte repertoires Immune cell migration and immune tissue organization Immune responses to pathogens high-throughput sequencing thema EDItEUR::M Medicine and Nursing Carmen Molina-Paris Ramit Mehr Miles Davenport Rob J. De Boer Veronika Zarnitsyna Michal Or-Guil Immune System Modeling and Analysis |
| title | Immune System Modeling and Analysis |
| title_full | Immune System Modeling and Analysis |
| title_fullStr | Immune System Modeling and Analysis |
| title_full_unstemmed | Immune System Modeling and Analysis |
| title_short | Immune System Modeling and Analysis |
| title_sort | immune system modeling and analysis |
| topic | R5-920 RC581-607 Immune cell differentiation Immune cell population dynamics and turnover Immunological diseases activation and signaling mathematical modeling immunomics Immune cell receptors lymphocyte repertoires Immune cell migration and immune tissue organization Immune responses to pathogens high-throughput sequencing thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RC581-607 Immune cell differentiation Immune cell population dynamics and turnover Immunological diseases activation and signaling mathematical modeling immunomics Immune cell receptors lymphocyte repertoires Immune cell migration and immune tissue organization Immune responses to pathogens high-throughput sequencing thema EDItEUR::M Medicine and Nursing |
| url | 17736 |
| work_keys_str_mv | AT carmenmolinaparis immunesystemmodelingandanalysis AT ramitmehr immunesystemmodelingandanalysis AT milesdavenport immunesystemmodelingandanalysis AT robjdeboer immunesystemmodelingandanalysis AT veronikazarnitsyna immunesystemmodelingandanalysis AT michalorguil immunesystemmodelingandanalysis |