Inhibiting PARP as a Strategic Target in Cancer

Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types have...

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Detalles Bibliográficos

Autores principales:	Kristin Zorn, Christina Annunziata
Formato:	Online
Lenguaje:	inglés
Publicado:	Frontiers Media SA 2021
Materias:	R5-920 RC254-282 DNA reapir PARP inhibitor Homologous Recombination combination therapy DNA Damage Cancer thema EDItEUR::M Medicine and Nursing
Acceso en línea:	18342
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