Intrinsic Clocks
"Intrinsic Clocks" presents an array of current research activities on intrinsic clocks and their contributions to biology and physiology. It elucidates the current models for the intrinsic clocks, their molecular components and key mechanisms as well as the key brain regions and animal models for t...
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| Principais autores: | , |
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| Formato: | Online |
| Idioma: | inglês |
| Publicado em: |
Frontiers Media SA
2021
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| Assuntos: | |
| Acesso em linha: | 29680 |
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| _version_ | 1869523322604093440 |
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| author | Daniela D. Pollak Timo Partonen |
| author_browse | Daniela D. Pollak Timo Partonen |
| author_facet | Daniela D. Pollak Timo Partonen |
| author_sort | Daniela D. Pollak |
| collection | Directory of Open Access Books |
| description | "Intrinsic Clocks" presents an array of current research activities on intrinsic clocks and their contributions to biology and physiology. It elucidates the current models for the intrinsic clocks, their molecular components and key mechanisms as well as the key brain regions and animal models for their behavioral analysis. It provides a timely view on how these clocks guide behavior, and how their disruption may cause depressive-like behavior and impairment in cognitive functions. Thereby, any specific method by which the mood-related functions of the intrinsic clocks might be influenced bears therapeutic potential and has clinical interest. The importance of some of these mechanisms was highlighted by the 2017 award of the Nobel Prize in Physiology or Medicine to Jeffrey C. Hall, Michael Rosbash, and Michael W. Young for their discoveries of the genetic control of the daily biological rhythm. The key to the explanation was the discovery of transcription-translation feedback loops of the so-called “clock genes.” |
| format | Online |
| id | doab-20.500.12854ir-50580 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-505802024-03-31T13:09:54Z Intrinsic Clocks Daniela D. Pollak Timo Partonen R5-920 RC346-429 nocturnal circadian tanycytes hippocampus mood diurnal seasonal cryptochrome oscillation small-molecule thema EDItEUR::M Medicine and Nursing "Intrinsic Clocks" presents an array of current research activities on intrinsic clocks and their contributions to biology and physiology. It elucidates the current models for the intrinsic clocks, their molecular components and key mechanisms as well as the key brain regions and animal models for their behavioral analysis. It provides a timely view on how these clocks guide behavior, and how their disruption may cause depressive-like behavior and impairment in cognitive functions. Thereby, any specific method by which the mood-related functions of the intrinsic clocks might be influenced bears therapeutic potential and has clinical interest. The importance of some of these mechanisms was highlighted by the 2017 award of the Nobel Prize in Physiology or Medicine to Jeffrey C. Hall, Michael Rosbash, and Michael W. Young for their discoveries of the genetic control of the daily biological rhythm. The key to the explanation was the discovery of transcription-translation feedback loops of the so-called “clock genes.” 2021-02-11T16:35:27Z 2021-02-11T16:35:27Z 2018-11-16 17:17:57 2018 book 29680 16648714 9782889454518 https://directory.doabooks.org/handle/20.500.12854/50580 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/5001/intrinsic-clocks Frontiers Media SA 10.3389/978-2-88945-451-8 10.3389/978-2-88945-451-8 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889454518 117 open access |
| spellingShingle | R5-920 RC346-429 nocturnal circadian tanycytes hippocampus mood diurnal seasonal cryptochrome oscillation small-molecule thema EDItEUR::M Medicine and Nursing Daniela D. Pollak Timo Partonen Intrinsic Clocks |
| title | Intrinsic Clocks |
| title_full | Intrinsic Clocks |
| title_fullStr | Intrinsic Clocks |
| title_full_unstemmed | Intrinsic Clocks |
| title_short | Intrinsic Clocks |
| title_sort | intrinsic clocks |
| topic | R5-920 RC346-429 nocturnal circadian tanycytes hippocampus mood diurnal seasonal cryptochrome oscillation small-molecule thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RC346-429 nocturnal circadian tanycytes hippocampus mood diurnal seasonal cryptochrome oscillation small-molecule thema EDItEUR::M Medicine and Nursing |
| url | 29680 |
| work_keys_str_mv | AT danieladpollak intrinsicclocks AT timopartonen intrinsicclocks |