Ion Channel Trafficking and Cardiac Arrhythmias
A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane,...
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| 主要な著者: | , , , |
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| フォーマット: | Online |
| 言語: | 英語 |
| 出版事項: |
Frontiers Media SA
2021
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| 主題: | |
| オンライン･アクセス: | 32040 |
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| _version_ | 1869514526360076288 |
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| author | Marcel A.G. van der Heyden Brian P. Delisle Hugues Abriel Baoxin Li |
| author_browse | Baoxin Li Brian P. Delisle Hugues Abriel Marcel A.G. van der Heyden |
| author_facet | Marcel A.G. van der Heyden Brian P. Delisle Hugues Abriel Baoxin Li |
| author_sort | Marcel A.G. van der Heyden |
| collection | Directory of Open Access Books |
| description | A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane, and subsequently take them from the plasma membrane to the protein degradation machinery are commonly known as trafficking. The research field recognizes that aberrant channel trafficking stands at the basis of many congenital and acquired arrhythmias. The collection of papers in this eBook provides state-of-the-art insight into the world of ion channel trafficking research. |
| format | Online |
| id | doab-20.500.12854ir-50657 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-506572024-03-31T22:45:04Z Ion Channel Trafficking and Cardiac Arrhythmias Marcel A.G. van der Heyden Brian P. Delisle Hugues Abriel Baoxin Li QP1-981 Q1-390 Kv11.1 channels Connexin43 (Cx43) ion channel arrhythmia TRPM4 channel Glycosylation NaV1.5 channels Kir2.1 channels trafficking Autophagy Protein complexes thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane, and subsequently take them from the plasma membrane to the protein degradation machinery are commonly known as trafficking. The research field recognizes that aberrant channel trafficking stands at the basis of many congenital and acquired arrhythmias. The collection of papers in this eBook provides state-of-the-art insight into the world of ion channel trafficking research. 2021-02-11T16:40:43Z 2021-02-11T16:40:43Z 2019-01-23 14:53:43 2018 book 32040 16648714 9782889456437 https://directory.doabooks.org/handle/20.500.12854/50657 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/5514/ion-channel-trafficking-and-cardiac-arrhythmias Frontiers Media SA 10.3389/978-2-88945-643-7 10.3389/978-2-88945-643-7 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889456437 123 open access |
| spellingShingle | QP1-981 Q1-390 Kv11.1 channels Connexin43 (Cx43) ion channel arrhythmia TRPM4 channel Glycosylation NaV1.5 channels Kir2.1 channels trafficking Autophagy Protein complexes thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology Marcel A.G. van der Heyden Brian P. Delisle Hugues Abriel Baoxin Li Ion Channel Trafficking and Cardiac Arrhythmias |
| title | Ion Channel Trafficking and Cardiac Arrhythmias |
| title_full | Ion Channel Trafficking and Cardiac Arrhythmias |
| title_fullStr | Ion Channel Trafficking and Cardiac Arrhythmias |
| title_full_unstemmed | Ion Channel Trafficking and Cardiac Arrhythmias |
| title_short | Ion Channel Trafficking and Cardiac Arrhythmias |
| title_sort | ion channel trafficking and cardiac arrhythmias |
| topic | QP1-981 Q1-390 Kv11.1 channels Connexin43 (Cx43) ion channel arrhythmia TRPM4 channel Glycosylation NaV1.5 channels Kir2.1 channels trafficking Autophagy Protein complexes thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology |
| topic_facet | QP1-981 Q1-390 Kv11.1 channels Connexin43 (Cx43) ion channel arrhythmia TRPM4 channel Glycosylation NaV1.5 channels Kir2.1 channels trafficking Autophagy Protein complexes thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology |
| url | 32040 |
| work_keys_str_mv | AT marcelagvanderheyden ionchanneltraffickingandcardiacarrhythmias AT brianpdelisle ionchanneltraffickingandcardiacarrhythmias AT huguesabriel ionchanneltraffickingandcardiacarrhythmias AT baoxinli ionchanneltraffickingandcardiacarrhythmias |