Marine Glycobiology, Glycomics and Lectins

Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular pro...

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主要作者: Ozeki, Yasuhiro
格式: Online
語言:英语
出版: MDPI - Multidisciplinary Digital Publishing Institute 2021
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author Ozeki, Yasuhiro
author_browse Ozeki, Yasuhiro
author_facet Ozeki, Yasuhiro
author_sort Ozeki, Yasuhiro
collection Directory of Open Access Books
description Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences.This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined.
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spelling doab-20.500.12854ir-527752024-04-05T12:33:40Z Marine Glycobiology, Glycomics and Lectins Ozeki, Yasuhiro QH301-705.5 QD415-436 Q1-390 toxicity anticoagulant activities Portunus pelagicus complement system Fucus distichus subsp. evanescens MytiLec-1 DNA methyltransferases malignant glioma heparin innate immunity polysialic acid (polySia) HddSBL differentiation induction phagocytosis fucosylated glycosaminoglycan Alzheimer’s disease thermostable amyloid-? lectins ?-secretase fucoidan oncolytic vaccinia virus Marinomonas viral replication BACE1 glioblastoma bioactivity Ehrlich ascites carcinoma adverse effects therapeutic effects ERK physicochemical characteristics oligo-fucoidan tandem duplication lectin galactooligosaccharides recombinant TTL theoretical model fucan sulfate retinal pigment epithelium glycosaminoglycan ?-galactosidase apoptosis-related genes C1q VEGF nanomedical devices epigenetic modification nematocyst discharge process Mytilus galloprovincialis pattern recognition receptors Pattalus mollis transglycosylation anti-viral nematogalectin heparan sulphate oxidative stress bivalve mollusks thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences.This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined. 2021-02-11T18:47:58Z 2021-02-11T18:47:58Z 2019-12-09 16:39:37 2019 book 42723 9783039218202 9783039218219 https://directory.doabooks.org/handle/20.500.12854/52775 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1825 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03921-821-9 10.3390/books978-3-03921-821-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039218202 9783039218219 176 open access
spellingShingle QH301-705.5
QD415-436
Q1-390
toxicity
anticoagulant activities
Portunus pelagicus
complement system
Fucus distichus subsp. evanescens
MytiLec-1
DNA methyltransferases
malignant glioma
heparin
innate immunity
polysialic acid (polySia)
HddSBL
differentiation induction
phagocytosis
fucosylated glycosaminoglycan
Alzheimer’s disease
thermostable
amyloid-?
lectins
?-secretase
fucoidan
oncolytic vaccinia virus
Marinomonas
viral replication
BACE1
glioblastoma
bioactivity
Ehrlich ascites carcinoma
adverse effects
therapeutic effects
ERK
physicochemical characteristics
oligo-fucoidan
tandem duplication
lectin
galactooligosaccharides
recombinant
TTL
theoretical model
fucan sulfate
retinal pigment epithelium
glycosaminoglycan
?-galactosidase
apoptosis-related genes
C1q
VEGF
nanomedical devices
epigenetic modification
nematocyst discharge process
Mytilus galloprovincialis
pattern recognition receptors
Pattalus mollis
transglycosylation
anti-viral
nematogalectin
heparan sulphate
oxidative stress
bivalve mollusks
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Ozeki, Yasuhiro
Marine Glycobiology, Glycomics and Lectins
title Marine Glycobiology, Glycomics and Lectins
title_full Marine Glycobiology, Glycomics and Lectins
title_fullStr Marine Glycobiology, Glycomics and Lectins
title_full_unstemmed Marine Glycobiology, Glycomics and Lectins
title_short Marine Glycobiology, Glycomics and Lectins
title_sort marine glycobiology glycomics and lectins
topic QH301-705.5
QD415-436
Q1-390
toxicity
anticoagulant activities
Portunus pelagicus
complement system
Fucus distichus subsp. evanescens
MytiLec-1
DNA methyltransferases
malignant glioma
heparin
innate immunity
polysialic acid (polySia)
HddSBL
differentiation induction
phagocytosis
fucosylated glycosaminoglycan
Alzheimer’s disease
thermostable
amyloid-?
lectins
?-secretase
fucoidan
oncolytic vaccinia virus
Marinomonas
viral replication
BACE1
glioblastoma
bioactivity
Ehrlich ascites carcinoma
adverse effects
therapeutic effects
ERK
physicochemical characteristics
oligo-fucoidan
tandem duplication
lectin
galactooligosaccharides
recombinant
TTL
theoretical model
fucan sulfate
retinal pigment epithelium
glycosaminoglycan
?-galactosidase
apoptosis-related genes
C1q
VEGF
nanomedical devices
epigenetic modification
nematocyst discharge process
Mytilus galloprovincialis
pattern recognition receptors
Pattalus mollis
transglycosylation
anti-viral
nematogalectin
heparan sulphate
oxidative stress
bivalve mollusks
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet QH301-705.5
QD415-436
Q1-390
toxicity
anticoagulant activities
Portunus pelagicus
complement system
Fucus distichus subsp. evanescens
MytiLec-1
DNA methyltransferases
malignant glioma
heparin
innate immunity
polysialic acid (polySia)
HddSBL
differentiation induction
phagocytosis
fucosylated glycosaminoglycan
Alzheimer’s disease
thermostable
amyloid-?
lectins
?-secretase
fucoidan
oncolytic vaccinia virus
Marinomonas
viral replication
BACE1
glioblastoma
bioactivity
Ehrlich ascites carcinoma
adverse effects
therapeutic effects
ERK
physicochemical characteristics
oligo-fucoidan
tandem duplication
lectin
galactooligosaccharides
recombinant
TTL
theoretical model
fucan sulfate
retinal pigment epithelium
glycosaminoglycan
?-galactosidase
apoptosis-related genes
C1q
VEGF
nanomedical devices
epigenetic modification
nematocyst discharge process
Mytilus galloprovincialis
pattern recognition receptors
Pattalus mollis
transglycosylation
anti-viral
nematogalectin
heparan sulphate
oxidative stress
bivalve mollusks
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url 42723
work_keys_str_mv AT ozekiyasuhiro marineglycobiologyglycomicsandlectins