Mechanisms of Mitotic Chromosome Segregation

This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background...

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Prif Awdur: J. Richard McIntosh
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Iaith:Saesneg
Cyhoeddwyd: MDPI - Multidisciplinary Digital Publishing Institute 2021
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Mynediad Ar-lein:21915
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author J. Richard McIntosh
author_browse J. Richard McIntosh
author_facet J. Richard McIntosh
author_sort J. Richard McIntosh
collection Directory of Open Access Books
description This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.
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language eng
publishDate 2021
publishDateRange 2021
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-529452024-04-05T12:33:11Z Mechanisms of Mitotic Chromosome Segregation J. Richard McIntosh QH301-705.5 genome stability Trisomies microtubule dynamics Checkpoints Inheritance Cell division centrosome Down Syndrome Cell motility Cell regulation chromosome segregation Microtubules Cell cycle kinetochore Cytoskeleton Cell reproduction thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level. 2021-02-11T19:01:16Z 2021-02-11T19:01:16Z 2017-05-10 09:52:09 2017 book 21915 9783038424031 9783038424024 https://directory.doabooks.org/handle/20.500.12854/52945 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://sci.fo/33r http://www.mdpi.com/books/pdfview/book/286 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038424031 9783038424024 VIII, 332 open access
spellingShingle QH301-705.5
genome stability
Trisomies
microtubule dynamics
Checkpoints
Inheritance
Cell division
centrosome
Down Syndrome
Cell motility
Cell regulation
chromosome segregation
Microtubules
Cell cycle
kinetochore
Cytoskeleton
Cell reproduction
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
J. Richard McIntosh
Mechanisms of Mitotic Chromosome Segregation
title Mechanisms of Mitotic Chromosome Segregation
title_full Mechanisms of Mitotic Chromosome Segregation
title_fullStr Mechanisms of Mitotic Chromosome Segregation
title_full_unstemmed Mechanisms of Mitotic Chromosome Segregation
title_short Mechanisms of Mitotic Chromosome Segregation
title_sort mechanisms of mitotic chromosome segregation
topic QH301-705.5
genome stability
Trisomies
microtubule dynamics
Checkpoints
Inheritance
Cell division
centrosome
Down Syndrome
Cell motility
Cell regulation
chromosome segregation
Microtubules
Cell cycle
kinetochore
Cytoskeleton
Cell reproduction
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet QH301-705.5
genome stability
Trisomies
microtubule dynamics
Checkpoints
Inheritance
Cell division
centrosome
Down Syndrome
Cell motility
Cell regulation
chromosome segregation
Microtubules
Cell cycle
kinetochore
Cytoskeleton
Cell reproduction
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url 21915
work_keys_str_mv AT jrichardmcintosh mechanismsofmitoticchromosomesegregation