Mechanisms of Neural Circuit Formation
The formation of the proper pattern of neuronal circuits during development is critical for the normal function of the vertebrate brain and for the survival of the organism. Circuit tracing studies spanning the past 100 years have revealed the beauty and exquisite intricacy of this pattern, which re...
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| Главные авторы: | , , |
|---|---|
| Формат: | Online |
| Язык: | английский |
| Опубликовано: |
Frontiers Media SA
2021
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| Предметы: | |
| Online-ссылка: | 17796 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869516463914614784 |
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| author | Robert W. Burgess Joshua A. Weiner James Jontes |
| author_browse | James Jontes Joshua A. Weiner Robert W. Burgess |
| author_facet | Robert W. Burgess Joshua A. Weiner James Jontes |
| author_sort | Robert W. Burgess |
| collection | Directory of Open Access Books |
| description | The formation of the proper pattern of neuronal circuits during development is critical for the normal function of the vertebrate brain and for the survival of the organism. Circuit tracing studies spanning the past 100 years have revealed the beauty and exquisite intricacy of this pattern, which represents the most complex biological system known. In humans, aberrant circuit formation is a likely underlying cause of a wide variety of birth defects and neurological disorders, including autism, intellectual disability, and schizophrenia. Furthermore, future therapeutic approaches to restoring the function of damaged neural circuits will require a better understanding of the developmental constraints under which those circuits were originally assembled. For these reasons, elucidating the molecular mechanisms of neural circuit formation is a major goal of neurobiology today. |
| format | Online |
| id | doab-20.500.12854ir-52946 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-529462024-04-05T12:35:38Z Mechanisms of Neural Circuit Formation Robert W. Burgess Joshua A. Weiner James Jontes RC321-571 Q1-390 neural circuit dendrite arborization Cell Adhesion Molecules axon guidance synapse formation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences The formation of the proper pattern of neuronal circuits during development is critical for the normal function of the vertebrate brain and for the survival of the organism. Circuit tracing studies spanning the past 100 years have revealed the beauty and exquisite intricacy of this pattern, which represents the most complex biological system known. In humans, aberrant circuit formation is a likely underlying cause of a wide variety of birth defects and neurological disorders, including autism, intellectual disability, and schizophrenia. Furthermore, future therapeutic approaches to restoring the function of damaged neural circuits will require a better understanding of the developmental constraints under which those circuits were originally assembled. For these reasons, elucidating the molecular mechanisms of neural circuit formation is a major goal of neurobiology today. 2021-02-11T19:01:17Z 2021-02-11T19:01:17Z 2015-12-10 11:59:06 2015 book 17796 16648714 9782889194032 https://directory.doabooks.org/handle/20.500.12854/52946 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Mechanisms_of_Neural_Circuit_Formation/428#nogo http://journal.frontiersin.org/researchtopic/296/mechanisms-of-neural-circuit-formation Frontiers Media SA 10.3389/978-2-88919-403-2 10.3389/978-2-88919-403-2 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889194032 179 open access |
| spellingShingle | RC321-571 Q1-390 neural circuit dendrite arborization Cell Adhesion Molecules axon guidance synapse formation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Robert W. Burgess Joshua A. Weiner James Jontes Mechanisms of Neural Circuit Formation |
| title | Mechanisms of Neural Circuit Formation |
| title_full | Mechanisms of Neural Circuit Formation |
| title_fullStr | Mechanisms of Neural Circuit Formation |
| title_full_unstemmed | Mechanisms of Neural Circuit Formation |
| title_short | Mechanisms of Neural Circuit Formation |
| title_sort | mechanisms of neural circuit formation |
| topic | RC321-571 Q1-390 neural circuit dendrite arborization Cell Adhesion Molecules axon guidance synapse formation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | RC321-571 Q1-390 neural circuit dendrite arborization Cell Adhesion Molecules axon guidance synapse formation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | 17796 |
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