Micro/Nano Devices for Blood Analysis

The development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there...

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Hoofdauteurs: Minas, Graça, Catarino, Susana, Lima, Rui A.
Formaat: Online
Taal:Engels
Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2021
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author Minas, Graça
Catarino, Susana
Lima, Rui A.
author_browse Catarino, Susana
Lima, Rui A.
Minas, Graça
author_facet Minas, Graça
Catarino, Susana
Lima, Rui A.
author_sort Minas, Graça
collection Directory of Open Access Books
description The development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there has been a notably fast development in the miniaturization of mechanical microdevices, later known as microelectromechanical systems (MEMS), which combine electrical and mechanical components at a microscale level. The integration of microflow and optical components in MEMS microdevices, as well as the development of micropumps and microvalves, have promoted the interest of several research fields dealing with fluid flow and transport phenomena happening in microscale devices. Microfluidic systems have many advantages over their macroscale counterparts, offering the ability to work with small sample volumes, providing good manipulation and control of samples, decreasing reaction times, and allowing parallel operations in one single step. As a consequence, microdevices offer great potential for the development of portable and point-of-care diagnostic devices, particularly for blood analysis. Moreover, the recent progress in nanotechnology has contributed to its increasing popularity, and has expanded the areas of application of microfluidic devices, including in the manipulation and analysis of flows on the scale of DNA, proteins, and nanoparticles (nanoflows). In this Special Issue, we invited contributions (original research papers, review articles, and brief communications) that focus on the latest advances and challenges in micro- and nanodevices for diagnostics and blood analysis, micro- and nanofluidics, technologies for flow visualization, MEMS, biochips, and lab-on-a-chip devices and their application to research and industry. We hope to provide an opportunity to the engineering and biomedical community to exchange knowledge and information and to bring together researchers who are interested in the general field of MEMS and micro/nanofluidics and, especially, in its applications to biomedical areas.
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spelling doab-20.500.12854ir-533812024-04-09T23:16:24Z Micro/Nano Devices for Blood Analysis Minas, Graça Catarino, Susana Lima, Rui A. T1-995 red blood cells n/a metastatic potential microfluidic devices microstructure lens-less regression analysis power-law fluid narrow rectangular microchannel biomedical coatings XTC-YF cells red blood cell (RBC) aggregation Y-27632 finite element method POCT CEA detection immersed boundary method suspension particle tracking velocimetry biomicrofluidics computational fluid dynamics red blood cells (RBCs) modified conventional erythrocyte sedimentation rate (ESR) method computational biomechanics RBC aggregation index microfabrication microfluidics morphological analysis chronic renal disease multiple microfluidic channels centrifugal microfluidic device deformability master molder using xurography technique fluorescent chemiluminescence hydrophobic dish pressure-driven flow cell deformability mechanophenotyping separation and sorting techniques density medium cell adhesion polymers rheology circular microchannel blood on chips multinucleated cells velocity cell analysis microfluidic chip twin-image removal cancer Lattice–Boltzmann method diabetes hyperbolic microchannel thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues The development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there has been a notably fast development in the miniaturization of mechanical microdevices, later known as microelectromechanical systems (MEMS), which combine electrical and mechanical components at a microscale level. The integration of microflow and optical components in MEMS microdevices, as well as the development of micropumps and microvalves, have promoted the interest of several research fields dealing with fluid flow and transport phenomena happening in microscale devices. Microfluidic systems have many advantages over their macroscale counterparts, offering the ability to work with small sample volumes, providing good manipulation and control of samples, decreasing reaction times, and allowing parallel operations in one single step. As a consequence, microdevices offer great potential for the development of portable and point-of-care diagnostic devices, particularly for blood analysis. Moreover, the recent progress in nanotechnology has contributed to its increasing popularity, and has expanded the areas of application of microfluidic devices, including in the manipulation and analysis of flows on the scale of DNA, proteins, and nanoparticles (nanoflows). In this Special Issue, we invited contributions (original research papers, review articles, and brief communications) that focus on the latest advances and challenges in micro- and nanodevices for diagnostics and blood analysis, micro- and nanofluidics, technologies for flow visualization, MEMS, biochips, and lab-on-a-chip devices and their application to research and industry. We hope to provide an opportunity to the engineering and biomedical community to exchange knowledge and information and to bring together researchers who are interested in the general field of MEMS and micro/nanofluidics and, especially, in its applications to biomedical areas. 2021-02-11T19:31:04Z 2021-02-11T19:31:04Z 2020-01-07 09:08:26 2019 book 43205 9783039218240 9783039218257 https://directory.doabooks.org/handle/20.500.12854/53381 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1869 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03921-825-7 10.3390/books978-3-03921-825-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039218240 9783039218257 174 open access
spellingShingle T1-995
red blood cells
n/a
metastatic potential
microfluidic devices
microstructure
lens-less
regression analysis
power-law fluid
narrow rectangular microchannel
biomedical coatings
XTC-YF cells
red blood cell (RBC) aggregation
Y-27632
finite element method
POCT
CEA detection
immersed boundary method
suspension
particle tracking velocimetry
biomicrofluidics
computational fluid dynamics
red blood cells (RBCs)
modified conventional erythrocyte sedimentation rate (ESR) method
computational biomechanics
RBC aggregation index
microfabrication
microfluidics
morphological analysis
chronic renal disease
multiple microfluidic channels
centrifugal microfluidic device
deformability
master molder using xurography technique
fluorescent chemiluminescence
hydrophobic dish
pressure-driven flow
cell deformability
mechanophenotyping
separation and sorting techniques
density medium
cell adhesion
polymers
rheology
circular microchannel
blood on chips
multinucleated cells
velocity
cell analysis
microfluidic chip
twin-image removal
cancer
Lattice–Boltzmann method
diabetes
hyperbolic microchannel
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
Minas, Graça
Catarino, Susana
Lima, Rui A.
Micro/Nano Devices for Blood Analysis
title Micro/Nano Devices for Blood Analysis
title_full Micro/Nano Devices for Blood Analysis
title_fullStr Micro/Nano Devices for Blood Analysis
title_full_unstemmed Micro/Nano Devices for Blood Analysis
title_short Micro/Nano Devices for Blood Analysis
title_sort micro nano devices for blood analysis
topic T1-995
red blood cells
n/a
metastatic potential
microfluidic devices
microstructure
lens-less
regression analysis
power-law fluid
narrow rectangular microchannel
biomedical coatings
XTC-YF cells
red blood cell (RBC) aggregation
Y-27632
finite element method
POCT
CEA detection
immersed boundary method
suspension
particle tracking velocimetry
biomicrofluidics
computational fluid dynamics
red blood cells (RBCs)
modified conventional erythrocyte sedimentation rate (ESR) method
computational biomechanics
RBC aggregation index
microfabrication
microfluidics
morphological analysis
chronic renal disease
multiple microfluidic channels
centrifugal microfluidic device
deformability
master molder using xurography technique
fluorescent chemiluminescence
hydrophobic dish
pressure-driven flow
cell deformability
mechanophenotyping
separation and sorting techniques
density medium
cell adhesion
polymers
rheology
circular microchannel
blood on chips
multinucleated cells
velocity
cell analysis
microfluidic chip
twin-image removal
cancer
Lattice–Boltzmann method
diabetes
hyperbolic microchannel
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
topic_facet T1-995
red blood cells
n/a
metastatic potential
microfluidic devices
microstructure
lens-less
regression analysis
power-law fluid
narrow rectangular microchannel
biomedical coatings
XTC-YF cells
red blood cell (RBC) aggregation
Y-27632
finite element method
POCT
CEA detection
immersed boundary method
suspension
particle tracking velocimetry
biomicrofluidics
computational fluid dynamics
red blood cells (RBCs)
modified conventional erythrocyte sedimentation rate (ESR) method
computational biomechanics
RBC aggregation index
microfabrication
microfluidics
morphological analysis
chronic renal disease
multiple microfluidic channels
centrifugal microfluidic device
deformability
master molder using xurography technique
fluorescent chemiluminescence
hydrophobic dish
pressure-driven flow
cell deformability
mechanophenotyping
separation and sorting techniques
density medium
cell adhesion
polymers
rheology
circular microchannel
blood on chips
multinucleated cells
velocity
cell analysis
microfluidic chip
twin-image removal
cancer
Lattice–Boltzmann method
diabetes
hyperbolic microchannel
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
url 43205
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