Microenvironment-Derived Stem Cell Plasticity
Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions,...
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| Fformat: | Online |
| Iaith: | Saesneg |
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Frontiers Media SA
2021
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| Mynediad Ar-lein: | 25644 |
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Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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| _version_ | 1869522088987983872 |
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| author | Marietta Herrmann Slavko Mojsilovic Jelena Krstic Ivana Gadjanski |
| author_browse | Ivana Gadjanski Jelena Krstic Marietta Herrmann Slavko Mojsilovic |
| author_facet | Marietta Herrmann Slavko Mojsilovic Jelena Krstic Ivana Gadjanski |
| author_sort | Marietta Herrmann |
| collection | Directory of Open Access Books |
| description | Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue. |
| format | Online |
| id | doab-20.500.12854ir-53417 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-534172024-03-30T23:22:59Z Microenvironment-Derived Stem Cell Plasticity Marietta Herrmann Slavko Mojsilovic Jelena Krstic Ivana Gadjanski R5-920 QH301-705.5 RC581-607 Q1-390 microenvironment stem cells tissue regeneration immunomodulation extracellular vesicles (EVs) oxygen tension plasticity imaging thema EDItEUR::M Medicine and Nursing Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue. 2021-02-11T19:33:24Z 2021-02-11T19:33:24Z 2018-02-27 16:16:45 2017 book 25644 16648714 9782889453443 https://directory.doabooks.org/handle/20.500.12854/53417 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/books/Microenvironment-Derived_Stem_Cell_Plasticity/1416 https://www.frontiersin.org/research-topics/4681/microenvironment-derived-stem-cell-plasticity Frontiers Media SA 10.3389/978-2-88945-344-3 10.3389/978-2-88945-344-3 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453443 114 open access |
| spellingShingle | R5-920 QH301-705.5 RC581-607 Q1-390 microenvironment stem cells tissue regeneration immunomodulation extracellular vesicles (EVs) oxygen tension plasticity imaging thema EDItEUR::M Medicine and Nursing Marietta Herrmann Slavko Mojsilovic Jelena Krstic Ivana Gadjanski Microenvironment-Derived Stem Cell Plasticity |
| title | Microenvironment-Derived Stem Cell Plasticity |
| title_full | Microenvironment-Derived Stem Cell Plasticity |
| title_fullStr | Microenvironment-Derived Stem Cell Plasticity |
| title_full_unstemmed | Microenvironment-Derived Stem Cell Plasticity |
| title_short | Microenvironment-Derived Stem Cell Plasticity |
| title_sort | microenvironment derived stem cell plasticity |
| topic | R5-920 QH301-705.5 RC581-607 Q1-390 microenvironment stem cells tissue regeneration immunomodulation extracellular vesicles (EVs) oxygen tension plasticity imaging thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 QH301-705.5 RC581-607 Q1-390 microenvironment stem cells tissue regeneration immunomodulation extracellular vesicles (EVs) oxygen tension plasticity imaging thema EDItEUR::M Medicine and Nursing |
| url | 25644 |
| work_keys_str_mv | AT mariettaherrmann microenvironmentderivedstemcellplasticity AT slavkomojsilovic microenvironmentderivedstemcellplasticity AT jelenakrstic microenvironmentderivedstemcellplasticity AT ivanagadjanski microenvironmentderivedstemcellplasticity |