Mitogen Activated Protein Kinases
Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved in all eukaryotes and allow cells to respond to changes in the physical and chemical properties of the environment and to produce an appropriate response by altering many cellular functions. MAPKs are among the most intens...
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| Główni autorzy: | , , |
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| Format: | Online |
| Język: | angielski |
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Frontiers Media SA
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | 25640 |
| Etykiety: |
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| _version_ | 1869527221889138688 |
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| author | Jose Lozano Jose M. Lizcano Ana Cuenda |
| author_browse | Ana Cuenda Jose Lozano Jose M. Lizcano |
| author_facet | Jose Lozano Jose M. Lizcano Ana Cuenda |
| author_sort | Jose Lozano |
| collection | Directory of Open Access Books |
| description | Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved in all eukaryotes and allow cells to respond to changes in the physical and chemical properties of the environment and to produce an appropriate response by altering many cellular functions. MAPKs are among the most intensively studied signal transduction systems. MAPK research is a very dynamic field in which new perspectives are continuously opening to the scientific community. Importantly, many MAPK inhibitors have been developed during the last years and are currently being tested in preclinical and clinical assays for inflammatory diseases and cancer treatment. In this research topic, we have gathered 14 papers covering recent advances in different aspects of the MAPK research area that have provided valuable insight into the spatiotemporal dynamics, the regulation and functions of MAPK pathways, as well as their therapeutic potential. We hope that this Research Topic helps readers to have a better understanding of the progresses that have been made recently in the field of MAPK signalling. A deeper understanding of the these pathways will facilitate the development of innovative therapeutic approaches. |
| format | Online |
| id | doab-20.500.12854ir-53610 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-536102024-04-05T12:33:21Z Mitogen Activated Protein Kinases Jose Lozano Jose M. Lizcano Ana Cuenda QH301-705.5 Q1-390 kinase cell differentiation p38 MSK scaffold inflammation JNK cancer MAPK ERK thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved in all eukaryotes and allow cells to respond to changes in the physical and chemical properties of the environment and to produce an appropriate response by altering many cellular functions. MAPKs are among the most intensively studied signal transduction systems. MAPK research is a very dynamic field in which new perspectives are continuously opening to the scientific community. Importantly, many MAPK inhibitors have been developed during the last years and are currently being tested in preclinical and clinical assays for inflammatory diseases and cancer treatment. In this research topic, we have gathered 14 papers covering recent advances in different aspects of the MAPK research area that have provided valuable insight into the spatiotemporal dynamics, the regulation and functions of MAPK pathways, as well as their therapeutic potential. We hope that this Research Topic helps readers to have a better understanding of the progresses that have been made recently in the field of MAPK signalling. A deeper understanding of the these pathways will facilitate the development of innovative therapeutic approaches. 2021-02-11T19:48:10Z 2021-02-11T19:48:10Z 2018-02-27 16:16:45 2017 book 25640 16648714 9782889453399 https://directory.doabooks.org/handle/20.500.12854/53610 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/books/Mitogen_Activated_Protein_Kinases/1396 https://www.frontiersin.org/research-topics/4006/mitogen-activated-protein-kinases Frontiers Media SA 10.3389/978-2-88945-339-9 10.3389/978-2-88945-339-9 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453399 163 open access |
| spellingShingle | QH301-705.5 Q1-390 kinase cell differentiation p38 MSK scaffold inflammation JNK cancer MAPK ERK thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Jose Lozano Jose M. Lizcano Ana Cuenda Mitogen Activated Protein Kinases |
| title | Mitogen Activated Protein Kinases |
| title_full | Mitogen Activated Protein Kinases |
| title_fullStr | Mitogen Activated Protein Kinases |
| title_full_unstemmed | Mitogen Activated Protein Kinases |
| title_short | Mitogen Activated Protein Kinases |
| title_sort | mitogen activated protein kinases |
| topic | QH301-705.5 Q1-390 kinase cell differentiation p38 MSK scaffold inflammation JNK cancer MAPK ERK thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 Q1-390 kinase cell differentiation p38 MSK scaffold inflammation JNK cancer MAPK ERK thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 25640 |
| work_keys_str_mv | AT joselozano mitogenactivatedproteinkinases AT josemlizcano mitogenactivatedproteinkinases AT anacuenda mitogenactivatedproteinkinases |