Model organisms in inflammation and cancer
A link between inflammation and cancer was initially made by Rudolf Virchow back in the 19th century. Nowadays many cancers are considered dependent on inflammatory responses to microbial and damaged-self stimuli and both arms of immunity, innate and adaptive, are playing a role in promoting cancer....
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| Formaat: | Online |
| Taal: | Engels |
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Frontiers Media SA
2021
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| Online toegang: | 17699 |
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| _version_ | 1869522591986745344 |
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| author | Yiorgos Apidianakis Dominique Ferrandon |
| author_browse | Dominique Ferrandon Yiorgos Apidianakis |
| author_facet | Yiorgos Apidianakis Dominique Ferrandon |
| author_sort | Yiorgos Apidianakis |
| collection | Directory of Open Access Books |
| description | A link between inflammation and cancer was initially made by Rudolf Virchow back in the 19th century. Nowadays many cancers are considered dependent on inflammatory responses to microbial and damaged-self stimuli and both arms of immunity, innate and adaptive, are playing a role in promoting cancer. Moreover, besides environmental factors, opportunistic pathogens contribute to inflammation and cancer. Nevertheless, microbial influence on chronic disease is sometimes difficult to discern, especially in the context of polymicrobial communities, such as those found in the digestive tract. In this light, model organisms provide important insights into immune and growth signals that promote cancer, and suggest therapies that will selectively target potentially harmful microbes or modulate host responses. A number of review and opinion articles in this series address novel aspects and paradigms of the interactions between the microbiota and the host in relation to inflammation and cancer. |
| format | Online |
| id | doab-20.500.12854ir-53663 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-536632023-12-20T18:40:32Z Model organisms in inflammation and cancer Yiorgos Apidianakis Dominique Ferrandon Q1-390 RC109-216 microbiota mouse innate immunity Drosophila diet aging human Hologenome bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general A link between inflammation and cancer was initially made by Rudolf Virchow back in the 19th century. Nowadays many cancers are considered dependent on inflammatory responses to microbial and damaged-self stimuli and both arms of immunity, innate and adaptive, are playing a role in promoting cancer. Moreover, besides environmental factors, opportunistic pathogens contribute to inflammation and cancer. Nevertheless, microbial influence on chronic disease is sometimes difficult to discern, especially in the context of polymicrobial communities, such as those found in the digestive tract. In this light, model organisms provide important insights into immune and growth signals that promote cancer, and suggest therapies that will selectively target potentially harmful microbes or modulate host responses. A number of review and opinion articles in this series address novel aspects and paradigms of the interactions between the microbiota and the host in relation to inflammation and cancer. 2021-02-11T19:52:31Z 2021-02-11T19:52:31Z 2015-11-19 16:29:12 2014 book 17699 16648714 9782889193707 https://directory.doabooks.org/handle/20.500.12854/53663 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Model_organisms_in_inflammation_and_cancer/395 http://journal.frontiersin.org/researchtopic/1403/model-organisms-in-inflammation-and-cancer Frontiers Media SA 10.3389/978-2-88919-370-7 10.3389/978-2-88919-370-7 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193707 83 open access |
| spellingShingle | Q1-390 RC109-216 microbiota mouse innate immunity Drosophila diet aging human Hologenome bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general Yiorgos Apidianakis Dominique Ferrandon Model organisms in inflammation and cancer |
| title | Model organisms in inflammation and cancer |
| title_full | Model organisms in inflammation and cancer |
| title_fullStr | Model organisms in inflammation and cancer |
| title_full_unstemmed | Model organisms in inflammation and cancer |
| title_short | Model organisms in inflammation and cancer |
| title_sort | model organisms in inflammation and cancer |
| topic | Q1-390 RC109-216 microbiota mouse innate immunity Drosophila diet aging human Hologenome bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general |
| topic_facet | Q1-390 RC109-216 microbiota mouse innate immunity Drosophila diet aging human Hologenome bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general |
| url | 17699 |
| work_keys_str_mv | AT yiorgosapidianakis modelorganismsininflammationandcancer AT dominiqueferrandon modelorganismsininflammationandcancer |