Modeling of electrophysiology and tension development in the human heart
Comprehension of the beating of the human heart is important for cardiac research and will improve many clinical applications. Simulations based on models describing cardiac electro-mechanics can acquire insights into this behavior. This work focuses on the mathematical reconstruction of electrophys...
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| Format: | Online |
| Język: | niemiecki |
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KIT Scientific Publishing
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | 34956 |
| Etykiety: |
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| _version_ | 1869515259736227840 |
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| author | Seemann, Gunnar |
| author_browse | Seemann, Gunnar |
| author_facet | Seemann, Gunnar |
| author_sort | Seemann, Gunnar |
| collection | Directory of Open Access Books |
| description | Comprehension of the beating of the human heart is important for cardiac research and will improve many clinical applications. Simulations based on models describing cardiac electro-mechanics can acquire insights into this behavior. This work focuses on the mathematical reconstruction of electrophysiology, excitation conduction, and tension development in the human heart on the cellular and the tissue level. The tissue models represent accurate anatomical shapes of the atria and the ventricles and incorporate electrophysiological heterogeneity and anisotropic conduction. The simulations comprehend the physiological behavior of the ventricles and of the atrium including the sinoatrial node as well as pathological cases like ventricular and atrial fibrillation and genetic defects in ionic channels. |
| format | Online |
| id | doab-20.500.12854ir-53695 |
| institution | Directory of Open Access Books |
| language | ger |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | KIT Scientific Publishing |
| publisherStr | KIT Scientific Publishing |
| record_format | ojs |
| spelling | doab-20.500.12854ir-536952024-04-09T23:16:22Z Modeling of electrophysiology and tension development in the human heart Seemann, Gunnar T1-995 Heterogenität Gewebe Kardiologie Computersimulation Ionenkanal Aktionspotenzial Erregung Elektrophysiologie Muskelfaser Kraft Tachykardie thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues Comprehension of the beating of the human heart is important for cardiac research and will improve many clinical applications. Simulations based on models describing cardiac electro-mechanics can acquire insights into this behavior. This work focuses on the mathematical reconstruction of electrophysiology, excitation conduction, and tension development in the human heart on the cellular and the tissue level. The tissue models represent accurate anatomical shapes of the atria and the ventricles and incorporate electrophysiological heterogeneity and anisotropic conduction. The simulations comprehend the physiological behavior of the ventricles and of the atrium including the sinoatrial node as well as pathological cases like ventricular and atrial fibrillation and genetic defects in ionic channels. 2021-02-11T19:54:31Z 2021-02-11T19:54:31Z 2019-07-30 20:01:59 2005 book 34956 393730066X https://directory.doabooks.org/handle/20.500.12854/53695 ger image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://www.ksp.kit.edu/393730066X KIT Scientific Publishing 10.5445/KSP/1000003545 10.5445/KSP/1000003545 68fffc18-8f7b-44fa-ac7e-0b7d7d979bd2 393730066X XI, 233 p. open access |
| spellingShingle | T1-995 Heterogenität Gewebe Kardiologie Computersimulation Ionenkanal Aktionspotenzial Erregung Elektrophysiologie Muskelfaser Kraft Tachykardie thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues Seemann, Gunnar Modeling of electrophysiology and tension development in the human heart |
| title | Modeling of electrophysiology and tension development in the human heart |
| title_full | Modeling of electrophysiology and tension development in the human heart |
| title_fullStr | Modeling of electrophysiology and tension development in the human heart |
| title_full_unstemmed | Modeling of electrophysiology and tension development in the human heart |
| title_short | Modeling of electrophysiology and tension development in the human heart |
| title_sort | modeling of electrophysiology and tension development in the human heart |
| topic | T1-995 Heterogenität Gewebe Kardiologie Computersimulation Ionenkanal Aktionspotenzial Erregung Elektrophysiologie Muskelfaser Kraft Tachykardie thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| topic_facet | T1-995 Heterogenität Gewebe Kardiologie Computersimulation Ionenkanal Aktionspotenzial Erregung Elektrophysiologie Muskelfaser Kraft Tachykardie thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| url | 34956 |
| work_keys_str_mv | AT seemanngunnar modelingofelectrophysiologyandtensiondevelopmentinthehumanheart |