Modelling the human cardiac fluid mechanics

We present a virtual heart model simulating the flow in the left human ventricle and in the aorta. Because of the lack of in vivo structure data of the human ventricle, the active ventricle movement is given by a time-dependent ventricle model that is derived from in vivo image data of a nuclear spi...

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Glavni autor: Oertel, Herbert
Format: Online
Jezik:engleski
Izdano: KIT Scientific Publishing 2021
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author Oertel, Herbert
author_browse Oertel, Herbert
author_facet Oertel, Herbert
author_sort Oertel, Herbert
collection Directory of Open Access Books
description We present a virtual heart model simulating the flow in the left human ventricle and in the aorta. Because of the lack of in vivo structure data of the human ventricle, the active ventricle movement is given by a time-dependent ventricle model that is derived from in vivo image data of a nuclear spin MRT tomograph of a healthy human heart. The passive part of the virtual heart model consists of a model aorta and vena cava, and of heart valves. As the movement is due to the flow in the inactive region of the heart, a coupling of flow and structure is necessary in the model to take into account the deviation of the aorta and the closing and opening of the heart valves. The flow calculation is performed with a finite volume method, while the structure of the aorta is calculated using the finite element method. The flow resistance of the time simulation in the body is taken into account with a circulation model. In the outlook of the article, we show how the virtual heart model can be used to predict flow losses due to pathological ventricle contraction defects in an unhealthy human heart.
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spelling doab-20.500.12854ir-537472024-04-09T23:16:32Z Modelling the human cardiac fluid mechanics Oertel, Herbert T1-995 pathological ventricle defects Computer Fluid Dynamics in vivo left human ventricle MRI tomography thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues We present a virtual heart model simulating the flow in the left human ventricle and in the aorta. Because of the lack of in vivo structure data of the human ventricle, the active ventricle movement is given by a time-dependent ventricle model that is derived from in vivo image data of a nuclear spin MRT tomograph of a healthy human heart. The passive part of the virtual heart model consists of a model aorta and vena cava, and of heart valves. As the movement is due to the flow in the inactive region of the heart, a coupling of flow and structure is necessary in the model to take into account the deviation of the aorta and the closing and opening of the heart valves. The flow calculation is performed with a finite volume method, while the structure of the aorta is calculated using the finite element method. The flow resistance of the time simulation in the body is taken into account with a circulation model. In the outlook of the article, we show how the virtual heart model can be used to predict flow losses due to pathological ventricle contraction defects in an unhealthy human heart. 2021-02-11T19:58:29Z 2021-02-11T19:58:29Z 2019-07-30 20:01:58 2005 book 34580 3937300821 https://directory.doabooks.org/handle/20.500.12854/53747 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://www.ksp.kit.edu/3937300821 KIT Scientific Publishing 10.5445/KSP/1000003551 10.5445/KSP/1000003551 68fffc18-8f7b-44fa-ac7e-0b7d7d979bd2 3937300821 49 p. open access
spellingShingle T1-995
pathological ventricle defects
Computer Fluid Dynamics
in vivo
left human ventricle
MRI tomography
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
Oertel, Herbert
Modelling the human cardiac fluid mechanics
title Modelling the human cardiac fluid mechanics
title_full Modelling the human cardiac fluid mechanics
title_fullStr Modelling the human cardiac fluid mechanics
title_full_unstemmed Modelling the human cardiac fluid mechanics
title_short Modelling the human cardiac fluid mechanics
title_sort modelling the human cardiac fluid mechanics
topic T1-995
pathological ventricle defects
Computer Fluid Dynamics
in vivo
left human ventricle
MRI tomography
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
topic_facet T1-995
pathological ventricle defects
Computer Fluid Dynamics
in vivo
left human ventricle
MRI tomography
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
url 34580
work_keys_str_mv AT oertelherbert modellingthehumancardiacfluidmechanics