Molecular Chaperones and Neurodegeneration
Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered...
Պահպանված է:
| Հիմնական հեղինակներ: | , , |
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| Ձևաչափ: | Online |
| Լեզու: | անգլերեն |
| Հրապարակվել է: |
Frontiers Media SA
2021
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| Խորագրեր: | |
| Առցանց հասանելիություն: | 25642 |
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Չկան պիտակներ, Եղեք առաջինը, ով նշում է այս գրառումը!
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| _version_ | 1869523598790623232 |
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| author | Cintia Roodveldt Janice E. Braun Tiago F. Outeiro |
| author_browse | Cintia Roodveldt Janice E. Braun Tiago F. Outeiro |
| author_facet | Cintia Roodveldt Janice E. Braun Tiago F. Outeiro |
| author_sort | Cintia Roodveldt |
| collection | Directory of Open Access Books |
| description | Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered and several molecular mechanisms have been elucidated for many chaperones, while the field is being continuously challenged by new open questions. Probably as a consequence of the increasing research on the molecular bases of neurodegenerative diseases, and the realisation that many such disorders are linked to protein misfolding processes, unleashing the roles and mechanisms of chaperones in the context of neurodegeneration has become a prime scientific goal. This e-book contains a diversity of reviews, perspective and original research articles highlighting the importance and potential of this emerging subject. |
| format | Online |
| id | doab-20.500.12854ir-53828 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-538282024-04-05T17:29:29Z Molecular Chaperones and Neurodegeneration Cintia Roodveldt Janice E. Braun Tiago F. Outeiro RC321-571 Q1-390 molecular chaperone therapeutics neurodegenerative disease heat-shock response protein misfolding neuroprotection neurodegeneration heat-shock protein proteostasis amyloid protein thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered and several molecular mechanisms have been elucidated for many chaperones, while the field is being continuously challenged by new open questions. Probably as a consequence of the increasing research on the molecular bases of neurodegenerative diseases, and the realisation that many such disorders are linked to protein misfolding processes, unleashing the roles and mechanisms of chaperones in the context of neurodegeneration has become a prime scientific goal. This e-book contains a diversity of reviews, perspective and original research articles highlighting the importance and potential of this emerging subject. 2021-02-11T20:04:24Z 2021-02-11T20:04:24Z 2018-02-27 16:16:45 2017 book 25642 16648714 9782889453429 https://directory.doabooks.org/handle/20.500.12854/53828 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/books/Molecular_Chaperones_and_Neurodegeneration/1405 https://www.frontiersin.org/research-topics/4995/molecular-chaperones-and-neurodegeneration Frontiers Media SA 10.3389/978-2-88945-342-9 10.3389/978-2-88945-342-9 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453429 180 open access |
| spellingShingle | RC321-571 Q1-390 molecular chaperone therapeutics neurodegenerative disease heat-shock response protein misfolding neuroprotection neurodegeneration heat-shock protein proteostasis amyloid protein thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Cintia Roodveldt Janice E. Braun Tiago F. Outeiro Molecular Chaperones and Neurodegeneration |
| title | Molecular Chaperones and Neurodegeneration |
| title_full | Molecular Chaperones and Neurodegeneration |
| title_fullStr | Molecular Chaperones and Neurodegeneration |
| title_full_unstemmed | Molecular Chaperones and Neurodegeneration |
| title_short | Molecular Chaperones and Neurodegeneration |
| title_sort | molecular chaperones and neurodegeneration |
| topic | RC321-571 Q1-390 molecular chaperone therapeutics neurodegenerative disease heat-shock response protein misfolding neuroprotection neurodegeneration heat-shock protein proteostasis amyloid protein thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | RC321-571 Q1-390 molecular chaperone therapeutics neurodegenerative disease heat-shock response protein misfolding neuroprotection neurodegeneration heat-shock protein proteostasis amyloid protein thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | 25642 |
| work_keys_str_mv | AT cintiaroodveldt molecularchaperonesandneurodegeneration AT janiceebraun molecularchaperonesandneurodegeneration AT tiagofouteiro molecularchaperonesandneurodegeneration |