Molecular Features Distinguishing Gastric Cancer Subtypes
Gastric cancer is a leading cause of cancer deaths, but analysis of its molecular and clinical characteristics has been complicated by histological and aetiological heterogeneity. Stomach cancers are 90% adenocarcinoma; lymphoma, carcinoid, and stromal tumours may occur. Adenocarcinoma can be subdiv...
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| Materialtyp: | Online |
| Språk: | engelska |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Länkar: | 29760 |
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| _version_ | 1869522185604825088 |
|---|---|
| author | Valli De Re (Ed.) |
| author_browse | Valli De Re (Ed.) |
| author_facet | Valli De Re (Ed.) |
| author_sort | Valli De Re (Ed.) |
| collection | Directory of Open Access Books |
| description | Gastric cancer is a leading cause of cancer deaths, but analysis of its molecular and clinical characteristics has been complicated by histological and aetiological heterogeneity. Stomach cancers are 90% adenocarcinoma; lymphoma, carcinoid, and stromal tumours may occur. Adenocarcinoma can be subdivided into histological Lauren and the World Health Organization (WHO) classifications, but this information has not led to the development of histologic subtype-specific treatment options. One way to potentially improve treatment for gastric cancers is to better understand the pathogenesis of this disease, the contribution of Helicobacter pylori infection, and host immune response to lead to the development of integrated histological and molecular classification schemes for gastric cancer. The hope is that these studies may facilitate the development of clinical trials to explore therapies in defined sets of patients, ultimately improving survival from this deadly disease. |
| format | Online |
| id | doab-20.500.12854ir-53837 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-538372024-03-31T22:45:57Z Molecular Features Distinguishing Gastric Cancer Subtypes Valli De Re (Ed.) RC254-282 pathogenesis prognostic marker gastric cancer Helicobacter pylori proteomics immune response genomics diagnostic marker thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Gastric cancer is a leading cause of cancer deaths, but analysis of its molecular and clinical characteristics has been complicated by histological and aetiological heterogeneity. Stomach cancers are 90% adenocarcinoma; lymphoma, carcinoid, and stromal tumours may occur. Adenocarcinoma can be subdivided into histological Lauren and the World Health Organization (WHO) classifications, but this information has not led to the development of histologic subtype-specific treatment options. One way to potentially improve treatment for gastric cancers is to better understand the pathogenesis of this disease, the contribution of Helicobacter pylori infection, and host immune response to lead to the development of integrated histological and molecular classification schemes for gastric cancer. The hope is that these studies may facilitate the development of clinical trials to explore therapies in defined sets of patients, ultimately improving survival from this deadly disease. 2021-02-11T20:04:37Z 2021-02-11T20:04:37Z 2018-12-07 10:22:34 2018 book 29760 9783038974055 9783038974048 https://directory.doabooks.org/handle/20.500.12854/53837 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://play.google.com/books/publish/a/14935057684283403269#details/ISBN:9783038974048 https://www.mdpi.com/books/pdfview/book/1038 https://www.mdpi.com/books/pdfview/book/1038 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-405-5 10.3390/books978-3-03897-405-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038974055 9783038974048 326 open access |
| spellingShingle | RC254-282 pathogenesis prognostic marker gastric cancer Helicobacter pylori proteomics immune response genomics diagnostic marker thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Valli De Re (Ed.) Molecular Features Distinguishing Gastric Cancer Subtypes |
| title | Molecular Features Distinguishing Gastric Cancer Subtypes |
| title_full | Molecular Features Distinguishing Gastric Cancer Subtypes |
| title_fullStr | Molecular Features Distinguishing Gastric Cancer Subtypes |
| title_full_unstemmed | Molecular Features Distinguishing Gastric Cancer Subtypes |
| title_short | Molecular Features Distinguishing Gastric Cancer Subtypes |
| title_sort | molecular features distinguishing gastric cancer subtypes |
| topic | RC254-282 pathogenesis prognostic marker gastric cancer Helicobacter pylori proteomics immune response genomics diagnostic marker thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | RC254-282 pathogenesis prognostic marker gastric cancer Helicobacter pylori proteomics immune response genomics diagnostic marker thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | 29760 |
| work_keys_str_mv | AT vallidereed molecularfeaturesdistinguishinggastriccancersubtypes |