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Molecular Mechanism of Alzheimer's Disease

Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, th...

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Hovedforfatter: Macreadie, Ian
Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2021
Fag:
QH301-705.5
Q1-390
HOTAIR
neurosciences
sleep disturbance
positron emission tomography (PET)
vitamin B complex
neurodegeneration
Tau
miR-15/107
default-mode network
complement receptor 1
neuronal differentiation
epigenetics
brain glucose metabolism
oligomerization
genetic risk
A?O receptors
prion
ryanodine receptor
type 3 diabetes
complement
cognitive behavioral therapy for insomnia
cognitive function
epigenome-wide association study
Alzheimer’s disease
calcium signaling
?-secretase
tau
Prolyl isomerases
NEAT1
complement C3b/C4b receptor
proteostasis
amyloid beta
yeast
slow-wave sleep
amyloid ?
nutrition
4
protein aggregation
apolipoprotein E
dementia
MALAT1
inositol 1
lncRNAs
molecular biology
methylenetetrahydrofolate reductase MTHFR gene
5-trisphosphate receptor
CR1 density
miR-34c
aggregation
heat shock protein
dendritic spine
S-adenosylmethionine
beta amyloid
ion channel
inflammation
sleep fragmentation
cystathionine-?-lyase CTH gene
DNA methylation
heat shock response
microglia
drug target discovery
amyloid-? oligomer
therapy
CR1 length polymorphism
methylome
APOE gene
ubiquitin
magnetic resonance imaging (MRI)
neuronal degeneration
type 2 diabetes
Pin1
mild cognitive impairment
dairy products
endoplasmic reticulum
oxidative stress
Hispanics
CDK5R1
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Online adgang:42603
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