Molecular Organization of Membranes: Where Biology Meets Biophysics

Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and...

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Päätekijät: Marek Cebecauer, David Holowka
Aineistotyyppi: Online
Kieli:englanti
Julkaistu: Frontiers Media SA 2021
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Linkit:29641
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author Marek Cebecauer
David Holowka
author_browse David Holowka
Marek Cebecauer
author_facet Marek Cebecauer
David Holowka
author_sort Marek Cebecauer
collection Directory of Open Access Books
description Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ‘Molecular organisation of membranes: where biology meets biophysics’ was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field.
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spelling doab-20.500.12854ir-538532024-04-05T12:32:39Z Molecular Organization of Membranes: Where Biology Meets Biophysics Marek Cebecauer David Holowka QH301-705.5 Q1-390 Cell Membrane Caveolae Superresolution microscopy Nanodomains Membrane trafficking Membrane properties fluorescence microscopy Tetraspanins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ‘Molecular organisation of membranes: where biology meets biophysics’ was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field. 2021-02-11T20:05:10Z 2021-02-11T20:05:10Z 2018-11-16 17:17:57 2018 book 29641 16648714 9782889454099 https://directory.doabooks.org/handle/20.500.12854/53853 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/3239/molecular-organisation-of-membranes-where-biology-meets-biophysics Frontiers Media SA 10.3389/978-2-88945-409-9 10.3389/978-2-88945-409-9 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889454099 150 open access
spellingShingle QH301-705.5
Q1-390
Cell Membrane
Caveolae
Superresolution microscopy
Nanodomains
Membrane trafficking
Membrane properties
fluorescence microscopy
Tetraspanins
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Marek Cebecauer
David Holowka
Molecular Organization of Membranes: Where Biology Meets Biophysics
title Molecular Organization of Membranes: Where Biology Meets Biophysics
title_full Molecular Organization of Membranes: Where Biology Meets Biophysics
title_fullStr Molecular Organization of Membranes: Where Biology Meets Biophysics
title_full_unstemmed Molecular Organization of Membranes: Where Biology Meets Biophysics
title_short Molecular Organization of Membranes: Where Biology Meets Biophysics
title_sort molecular organization of membranes where biology meets biophysics
topic QH301-705.5
Q1-390
Cell Membrane
Caveolae
Superresolution microscopy
Nanodomains
Membrane trafficking
Membrane properties
fluorescence microscopy
Tetraspanins
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet QH301-705.5
Q1-390
Cell Membrane
Caveolae
Superresolution microscopy
Nanodomains
Membrane trafficking
Membrane properties
fluorescence microscopy
Tetraspanins
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url 29641
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