Molecular Pathways of Estrogen Receptor Action
ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Estrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that mainly function as ligand-inducible transcription...
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| Formato: | Online |
| Idioma: | inglês |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Acesso em linha: | 29156 |
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| _version_ | 1869522061831962624 |
|---|---|
| author | Farzed Pakdel (Ed.) |
| author_browse | Farzed Pakdel (Ed.) |
| author_facet | Farzed Pakdel (Ed.) |
| author_sort | Farzed Pakdel (Ed.) |
| collection | Directory of Open Access Books |
| description | ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Estrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that mainly function as ligand-inducible transcription factors that bind chromatin, as homodimers, at specific response elements. A tight reciprocal coupling between rapid ‘non-genomic’ and ‘genomic’ ER actions may also occur in many physiological processes. ERs have long been evaluated for their roles in controlling the expression of genes involved in vital cellular processes such as proliferation, apoptosis, and differentiation. Therefore, given the various and pleiotropic functions of ERs, the dysregulation of their pathways contributes to several diseases such as the hormone-dependent breast; endometrial and ovarian cancers; and neurodegenerative diseases, cardiovascular diseases, and osteoporosis. In this printed edition of the Special Issue, “Molecular Pathways of Estrogen Receptor Action”, promising results on understanding the mechanisms underlying ER-mediated effects in various pathophysiological processes are represented, covering different roles of ER pathways in the tumorigenesis, the resistance to endocrine therapy, the dynamics of 3D genome organization, and cross-talk with other signaling pathways. This Special Issue also provides insight into the emerging roles of estrogen-signaling pathways in lung cancer, the tumor microenvironment, and the immune system.] |
| format | Online |
| id | doab-20.500.12854ir-53856 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-538562024-04-05T12:32:44Z Molecular Pathways of Estrogen Receptor Action Farzed Pakdel (Ed.) QH301-705.5 Estrogens and estrogen receptors Cell signaling Physiopathology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Estrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that mainly function as ligand-inducible transcription factors that bind chromatin, as homodimers, at specific response elements. A tight reciprocal coupling between rapid ‘non-genomic’ and ‘genomic’ ER actions may also occur in many physiological processes. ERs have long been evaluated for their roles in controlling the expression of genes involved in vital cellular processes such as proliferation, apoptosis, and differentiation. Therefore, given the various and pleiotropic functions of ERs, the dysregulation of their pathways contributes to several diseases such as the hormone-dependent breast; endometrial and ovarian cancers; and neurodegenerative diseases, cardiovascular diseases, and osteoporosis. In this printed edition of the Special Issue, “Molecular Pathways of Estrogen Receptor Action”, promising results on understanding the mechanisms underlying ER-mediated effects in various pathophysiological processes are represented, covering different roles of ER pathways in the tumorigenesis, the resistance to endocrine therapy, the dynamics of 3D genome organization, and cross-talk with other signaling pathways. This Special Issue also provides insight into the emerging roles of estrogen-signaling pathways in lung cancer, the tumor microenvironment, and the immune system.] 2021-02-11T20:05:17Z 2021-02-11T20:05:17Z 2018-10-22 10:23:01 2018 book 29156 9783038972976 9783038972969 https://directory.doabooks.org/handle/20.500.12854/53856 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://www.mdpi.com/books/pdfview/book/818 https://play.google.com/books/publish/a/14935057684283403269#details/ISBN:9783038972969 https://www.mdpi.com/books/pdfview/book/818 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-297-6 10.3390/books978-3-03897-297-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038972976 9783038972969 304 open access |
| spellingShingle | QH301-705.5 Estrogens and estrogen receptors Cell signaling Physiopathology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Farzed Pakdel (Ed.) Molecular Pathways of Estrogen Receptor Action |
| title | Molecular Pathways of Estrogen Receptor Action |
| title_full | Molecular Pathways of Estrogen Receptor Action |
| title_fullStr | Molecular Pathways of Estrogen Receptor Action |
| title_full_unstemmed | Molecular Pathways of Estrogen Receptor Action |
| title_short | Molecular Pathways of Estrogen Receptor Action |
| title_sort | molecular pathways of estrogen receptor action |
| topic | QH301-705.5 Estrogens and estrogen receptors Cell signaling Physiopathology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 Estrogens and estrogen receptors Cell signaling Physiopathology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 29156 |
| work_keys_str_mv | AT farzedpakdeled molecularpathwaysofestrogenreceptoraction |