Molecular Pharmacology and Pathology of Strokes
Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the management of other factors, but no cure is yet av...
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| Huvudupphov: | , |
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| Materialtyp: | Online |
| Språk: | engelska |
| Utgiven: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Länkar: | 32217 |
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| _version_ | 1869522075954184192 |
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| author | Joen-Rong Sheu (Ed.) Howard Prentice (Ed.) |
| author_browse | Howard Prentice (Ed.) Joen-Rong Sheu (Ed.) |
| author_facet | Joen-Rong Sheu (Ed.) Howard Prentice (Ed.) |
| author_sort | Joen-Rong Sheu (Ed.) |
| collection | Directory of Open Access Books |
| description | Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the management of other factors, but no cure is yet available, despite new insights into molecular and therapeutic targets. Discoveries related to explicating the molecular pharmacology in cerebrovascular function and thrombosis have led to significant advancements in the current treatment paradigm for patients with stroke. Hence, this Special Issue invited scientific papers and reviews from researchers to provide solid evidence from a molecular point of view to scrutinize the molecular pharmacology and pathology of strokes. Platelet activation plays a major role in cardio and cerebrovascular diseases. Platelets also play a key role in the hemostatic process and are associated with various pathological events, such as arterial thrombosis and atherosclerosis. While the currently used anti-platelet drugs such as aspirin and clopidogrel demonstrate efficacy in many patients, they exert undesirable side effects. Therefore, the development of effective therapeutic strategies for the prevention and treatment of thrombotic diseases is a significant priority. Recently, precious metal drugs have conquered the subject of metal-based drugs, and several investigators have moved their attention to the synthesis of various ruthenium (Ru) and iridium (Ir) complexes due to their prospective therapeutic values. We have published this e-book about the “Molecular Pharmacology and Pathology of Strokes” and anticipate that readers will find this book useful regarding the significant challenges and current advances that are presently being made in stroke research, with the possibility of inspiring the application of novel drug development to enrich the devotion and treatment of patients with cardiovascular diseases. |
| format | Online |
| id | doab-20.500.12854ir-53857 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-538572024-03-30T23:22:58Z Molecular Pharmacology and Pathology of Strokes Joen-Rong Sheu (Ed.) Howard Prentice (Ed.) R5-920 RM1-950 RC666-701 Neuroprotection Vascular diseases Novel drug development Signal transductions Clinical and translational research Free radicals/oxidative stress Platelet activation and thrombosis thema EDItEUR::M Medicine and Nursing Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the management of other factors, but no cure is yet available, despite new insights into molecular and therapeutic targets. Discoveries related to explicating the molecular pharmacology in cerebrovascular function and thrombosis have led to significant advancements in the current treatment paradigm for patients with stroke. Hence, this Special Issue invited scientific papers and reviews from researchers to provide solid evidence from a molecular point of view to scrutinize the molecular pharmacology and pathology of strokes. Platelet activation plays a major role in cardio and cerebrovascular diseases. Platelets also play a key role in the hemostatic process and are associated with various pathological events, such as arterial thrombosis and atherosclerosis. While the currently used anti-platelet drugs such as aspirin and clopidogrel demonstrate efficacy in many patients, they exert undesirable side effects. Therefore, the development of effective therapeutic strategies for the prevention and treatment of thrombotic diseases is a significant priority. Recently, precious metal drugs have conquered the subject of metal-based drugs, and several investigators have moved their attention to the synthesis of various ruthenium (Ru) and iridium (Ir) complexes due to their prospective therapeutic values. We have published this e-book about the “Molecular Pharmacology and Pathology of Strokes” and anticipate that readers will find this book useful regarding the significant challenges and current advances that are presently being made in stroke research, with the possibility of inspiring the application of novel drug development to enrich the devotion and treatment of patients with cardiovascular diseases. 2021-02-11T20:05:19Z 2021-02-11T20:05:19Z 2019-02-11 11:33:53 2019 book 32217 9783038975410 9783038975427 https://directory.doabooks.org/handle/20.500.12854/53857 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://play.google.com/books/publish/a/14935057684283403269#details/ISBN:9783038975410 https://www.mdpi.com/books/pdfview/book/1133 https://www.mdpi.com/books/pdfview/book/1133 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-542-7 10.3390/books978-3-03897-542-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038975410 9783038975427 152 open access |
| spellingShingle | R5-920 RM1-950 RC666-701 Neuroprotection Vascular diseases Novel drug development Signal transductions Clinical and translational research Free radicals/oxidative stress Platelet activation and thrombosis thema EDItEUR::M Medicine and Nursing Joen-Rong Sheu (Ed.) Howard Prentice (Ed.) Molecular Pharmacology and Pathology of Strokes |
| title | Molecular Pharmacology and Pathology of Strokes |
| title_full | Molecular Pharmacology and Pathology of Strokes |
| title_fullStr | Molecular Pharmacology and Pathology of Strokes |
| title_full_unstemmed | Molecular Pharmacology and Pathology of Strokes |
| title_short | Molecular Pharmacology and Pathology of Strokes |
| title_sort | molecular pharmacology and pathology of strokes |
| topic | R5-920 RM1-950 RC666-701 Neuroprotection Vascular diseases Novel drug development Signal transductions Clinical and translational research Free radicals/oxidative stress Platelet activation and thrombosis thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RM1-950 RC666-701 Neuroprotection Vascular diseases Novel drug development Signal transductions Clinical and translational research Free radicals/oxidative stress Platelet activation and thrombosis thema EDItEUR::M Medicine and Nursing |
| url | 32217 |
| work_keys_str_mv | AT joenrongsheued molecularpharmacologyandpathologyofstrokes AT howardprenticeed molecularpharmacologyandpathologyofstrokes |