Molecular Research of Endometrial Pathophysiology
The endometrium has been the subject of intense research in a variety of clinical settings, because of its importance in the reproductive process and its role in women’s health. In the past 15 years, significant efforts have been invested in defining the molecular phenotype of the receptive phase en...
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| Format: | Online |
| Language: | English |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online Access: | 42704 |
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| _version_ | 1869518878866931712 |
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| author | Viganò, Paola Romano, Andrea |
| author_browse | Romano, Andrea Viganò, Paola |
| author_facet | Viganò, Paola Romano, Andrea |
| author_sort | Viganò, Paola |
| collection | Directory of Open Access Books |
| description | The endometrium has been the subject of intense research in a variety of clinical settings, because of its importance in the reproductive process and its role in women’s health. In the past 15 years, significant efforts have been invested in defining the molecular phenotype of the receptive phase endometrium as well as of various endometrial pathologies. Although this has generated a wealth of information on the molecular landscape of human endometrium, there is a need to complement this information in light of the novel methodologies and innovative technical approaches. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms of endometrium and endometrium-related disorders. The progress made in the molecular actions of steroids, in the metabolism of steroids and intracrinology, in endometrial intracellular pathways, in stem cells biology, as well as in the molecular alterations underlying endometrium-related pathologies has been the focus of the reviews and papers included. |
| format | Online |
| id | doab-20.500.12854ir-53860 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-538602023-12-20T15:54:27Z Molecular Research of Endometrial Pathophysiology Viganò, Paola Romano, Andrea HM401-1281 H1-99 endometrial stromal cells endometrial cell uterine cancer regeneration stem cell markers RANK chronic endometritis small RNA sequencing HOXA10 Vitamin D PPP2R1A molecular marker translational research angiogenesis endometriosis oestradiol mtDNA mutations antioxidant response protein phosphatase SMAP circulating tumour cells (CTCs) circulating tumour DNA (ctDNA) estrogen dependent endometrial regeneration mesenchymal stem cells endometrial cancer niche gene expression phosphoinositide 3-kinase lncRNAs mitochondrial biogenesis inflammation preclinical studies miRNA orthoxenograft tight junction proliferation aromatase testosterone CRISPR/Cas9 endometrium developmental pathway PP2A avatar infertility prognosis gene editing kinase inhibitor implantation haploinsufficiency contrast-enhanced CT scan pathway dehydroepiandrosterone (DHEA) CTCF PIK3CB zinc finger ectopic stroma liquid biopsy type II endometrial carcinoma eutopic and ectopic endometrium preclinical models EDN1 uterine aspirate cell contacts tumour suppressor gene pathogenomics mitochondrial dynamics adult stem cells PIK3CA murine models menstrual cycle immunomodulation decidualisation breakdown bioluminescence imaging protein kinase macrophages adherens junction exosomes immunohistochemistry orthotopic xenograft model decidualization p110? deficit of complex I targeted therapy mesenchymal stem cell sulfatase TRP channels personalized medicine mitophagy miR-375 migration microRNA gap junction cancer LGR5 miR-139-5p bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFP Social interaction The endometrium has been the subject of intense research in a variety of clinical settings, because of its importance in the reproductive process and its role in women’s health. In the past 15 years, significant efforts have been invested in defining the molecular phenotype of the receptive phase endometrium as well as of various endometrial pathologies. Although this has generated a wealth of information on the molecular landscape of human endometrium, there is a need to complement this information in light of the novel methodologies and innovative technical approaches. The focus of this International Journal of Molecular Sciences Special Issue is on molecular and cellular mechanisms of endometrium and endometrium-related disorders. The progress made in the molecular actions of steroids, in the metabolism of steroids and intracrinology, in endometrial intracellular pathways, in stem cells biology, as well as in the molecular alterations underlying endometrium-related pathologies has been the focus of the reviews and papers included. 2021-02-11T20:05:26Z 2021-02-11T20:05:26Z 2019-12-09 16:10:12 2019 book 42704 9783039214969 9783039214952 https://directory.doabooks.org/handle/20.500.12854/53860 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1707 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03921-496-9 10.3390/books978-3-03921-496-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039214969 9783039214952 378 open access |
| spellingShingle | HM401-1281 H1-99 endometrial stromal cells endometrial cell uterine cancer regeneration stem cell markers RANK chronic endometritis small RNA sequencing HOXA10 Vitamin D PPP2R1A molecular marker translational research angiogenesis endometriosis oestradiol mtDNA mutations antioxidant response protein phosphatase SMAP circulating tumour cells (CTCs) circulating tumour DNA (ctDNA) estrogen dependent endometrial regeneration mesenchymal stem cells endometrial cancer niche gene expression phosphoinositide 3-kinase lncRNAs mitochondrial biogenesis inflammation preclinical studies miRNA orthoxenograft tight junction proliferation aromatase testosterone CRISPR/Cas9 endometrium developmental pathway PP2A avatar infertility prognosis gene editing kinase inhibitor implantation haploinsufficiency contrast-enhanced CT scan pathway dehydroepiandrosterone (DHEA) CTCF PIK3CB zinc finger ectopic stroma liquid biopsy type II endometrial carcinoma eutopic and ectopic endometrium preclinical models EDN1 uterine aspirate cell contacts tumour suppressor gene pathogenomics mitochondrial dynamics adult stem cells PIK3CA murine models menstrual cycle immunomodulation decidualisation breakdown bioluminescence imaging protein kinase macrophages adherens junction exosomes immunohistochemistry orthotopic xenograft model decidualization p110? deficit of complex I targeted therapy mesenchymal stem cell sulfatase TRP channels personalized medicine mitophagy miR-375 migration microRNA gap junction cancer LGR5 miR-139-5p bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFP Social interaction Viganò, Paola Romano, Andrea Molecular Research of Endometrial Pathophysiology |
| title | Molecular Research of Endometrial Pathophysiology |
| title_full | Molecular Research of Endometrial Pathophysiology |
| title_fullStr | Molecular Research of Endometrial Pathophysiology |
| title_full_unstemmed | Molecular Research of Endometrial Pathophysiology |
| title_short | Molecular Research of Endometrial Pathophysiology |
| title_sort | molecular research of endometrial pathophysiology |
| topic | HM401-1281 H1-99 endometrial stromal cells endometrial cell uterine cancer regeneration stem cell markers RANK chronic endometritis small RNA sequencing HOXA10 Vitamin D PPP2R1A molecular marker translational research angiogenesis endometriosis oestradiol mtDNA mutations antioxidant response protein phosphatase SMAP circulating tumour cells (CTCs) circulating tumour DNA (ctDNA) estrogen dependent endometrial regeneration mesenchymal stem cells endometrial cancer niche gene expression phosphoinositide 3-kinase lncRNAs mitochondrial biogenesis inflammation preclinical studies miRNA orthoxenograft tight junction proliferation aromatase testosterone CRISPR/Cas9 endometrium developmental pathway PP2A avatar infertility prognosis gene editing kinase inhibitor implantation haploinsufficiency contrast-enhanced CT scan pathway dehydroepiandrosterone (DHEA) CTCF PIK3CB zinc finger ectopic stroma liquid biopsy type II endometrial carcinoma eutopic and ectopic endometrium preclinical models EDN1 uterine aspirate cell contacts tumour suppressor gene pathogenomics mitochondrial dynamics adult stem cells PIK3CA murine models menstrual cycle immunomodulation decidualisation breakdown bioluminescence imaging protein kinase macrophages adherens junction exosomes immunohistochemistry orthotopic xenograft model decidualization p110? deficit of complex I targeted therapy mesenchymal stem cell sulfatase TRP channels personalized medicine mitophagy miR-375 migration microRNA gap junction cancer LGR5 miR-139-5p bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFP Social interaction |
| topic_facet | HM401-1281 H1-99 endometrial stromal cells endometrial cell uterine cancer regeneration stem cell markers RANK chronic endometritis small RNA sequencing HOXA10 Vitamin D PPP2R1A molecular marker translational research angiogenesis endometriosis oestradiol mtDNA mutations antioxidant response protein phosphatase SMAP circulating tumour cells (CTCs) circulating tumour DNA (ctDNA) estrogen dependent endometrial regeneration mesenchymal stem cells endometrial cancer niche gene expression phosphoinositide 3-kinase lncRNAs mitochondrial biogenesis inflammation preclinical studies miRNA orthoxenograft tight junction proliferation aromatase testosterone CRISPR/Cas9 endometrium developmental pathway PP2A avatar infertility prognosis gene editing kinase inhibitor implantation haploinsufficiency contrast-enhanced CT scan pathway dehydroepiandrosterone (DHEA) CTCF PIK3CB zinc finger ectopic stroma liquid biopsy type II endometrial carcinoma eutopic and ectopic endometrium preclinical models EDN1 uterine aspirate cell contacts tumour suppressor gene pathogenomics mitochondrial dynamics adult stem cells PIK3CA murine models menstrual cycle immunomodulation decidualisation breakdown bioluminescence imaging protein kinase macrophages adherens junction exosomes immunohistochemistry orthotopic xenograft model decidualization p110? deficit of complex I targeted therapy mesenchymal stem cell sulfatase TRP channels personalized medicine mitophagy miR-375 migration microRNA gap junction cancer LGR5 miR-139-5p bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFP Social interaction |
| url | 42704 |
| work_keys_str_mv | AT viganopaola molecularresearchofendometrialpathophysiology AT romanoandrea molecularresearchofendometrialpathophysiology |