Monitoring endogenous GPCRs: lessons for drug design

G protein-coupled receptors (GPCRs) are integral membrane proteins forming the fourth largest superfamily in the human genome. Many of these receptors play key physiological roles and several pathologies have been associated with receptor functional abnormalities. GPCRs therefore represent important...

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Dettagli Bibliografici

Autore principale:	Dominique Massotte
Natura:	Online
Lingua:	inglese
Pubblicazione:	Frontiers Media SA 2021
Soggetti:	RM1-950 Q1-390 opioid receptors G protein coupled receptors CGamP mice FLIM fluorescent knock-in mice receptor heteromerization Endogenous receptors cannabinoid receptors biased signaling Opiate tolerance thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
Accesso online:	19554
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