Multidrug resistance in Cancer: Pharmacological Strategies from Basic Research to Clinical Issues

More than 40 years ago, the observation that doxorubicin-resistant tumor cells were cross-resistant to several structurally different anticancer agents was the first step in the discovery of P-glycoprotein (P-gp). P-gp belongs to the superfamily of ATP-binding cassette (ABC) transporters;its overexp...

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Auteurs principaux:	Chiara Riganti, Enrico Mini, Stefania Nobili
Format:	Online
Langue:	anglais
Publié:	Frontiers Media SA 2021
Sujets:	R5-920 RM1-950 RC254-282 Q1-390 multidrug resistance reversing strategies P-Glycoprotein Cancer thema EDItEUR::M Medicine and Nursing
Accès en ligne:	19523
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