Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology

Mycoplasma pneumoniae (Mp) is a major human pathogen that causes both upper and lower respiratory infections, and is one of the leading causes of community acquired pneumonia (CAP), accounting for 11–15% of CAP throughout the world. Additionally it is known to induce an inflammatory process which de...

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Main Authors: Takashi Shimizu, Ran Nir-Paz, Takeshi Saraya, Annemarie Van Rossum, Cecile Bebear
Format: Online
Language:English
Published: Frontiers Media SA 2021
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Online Access:25662
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author Takashi Shimizu
Ran Nir-Paz
Takeshi Saraya
Annemarie Van Rossum
Cecile Bebear
author_browse Annemarie Van Rossum
Cecile Bebear
Ran Nir-Paz
Takashi Shimizu
Takeshi Saraya
author_facet Takashi Shimizu
Ran Nir-Paz
Takeshi Saraya
Annemarie Van Rossum
Cecile Bebear
author_sort Takashi Shimizu
collection Directory of Open Access Books
description Mycoplasma pneumoniae (Mp) is a major human pathogen that causes both upper and lower respiratory infections, and is one of the leading causes of community acquired pneumonia (CAP), accounting for 11–15% of CAP throughout the world. Additionally it is known to induce an inflammatory process which depends on several mechanisms such as virulence of Mp (lipoproteins, community acquired respiratory distress syndrome (CARDS) toxin, oxidative products) and host defenses (cellular immunity and humoral immunity). Although it is a common pathogen, the pathogenesis for Mp infections is not yet fully understood. From the clinical point of view, since the pioneer studies in the 1960s and 1970s on the clinical presentation of Mp associated disease, the diagnostics approaches have changed dramatically leading to a better understanding of the clinical presentation and new issues have emerged - such as antibiotics resistance. The purpose of this Frontiers ebook is to thoroughly review and discuss the clinical presentation in view of the improved diagnostics, microbiological and immunological analysis of Mp infections, with focus on the history of Mp, clinical features of disease, bacterial structure of Mp and mechanism of gliding, clinical and laboratory diagnostics, the role of lipoproteins and Toll-like receptor, CARDS toxin, subtyping of Mp isolates and genome analysis, macrolide resistance and treatment.
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spelling doab-20.500.12854ir-541752024-03-30T23:21:48Z Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology Takashi Shimizu Ran Nir-Paz Takeshi Saraya Annemarie Van Rossum Cecile Bebear R5-920 QR1-502 Q1-390 pathogenesis epidemiology treatment clinical presentation antimicrobial resistance Mycoplasma pneumoniae outcome thema EDItEUR::M Medicine and Nursing Mycoplasma pneumoniae (Mp) is a major human pathogen that causes both upper and lower respiratory infections, and is one of the leading causes of community acquired pneumonia (CAP), accounting for 11–15% of CAP throughout the world. Additionally it is known to induce an inflammatory process which depends on several mechanisms such as virulence of Mp (lipoproteins, community acquired respiratory distress syndrome (CARDS) toxin, oxidative products) and host defenses (cellular immunity and humoral immunity). Although it is a common pathogen, the pathogenesis for Mp infections is not yet fully understood. From the clinical point of view, since the pioneer studies in the 1960s and 1970s on the clinical presentation of Mp associated disease, the diagnostics approaches have changed dramatically leading to a better understanding of the clinical presentation and new issues have emerged - such as antibiotics resistance. The purpose of this Frontiers ebook is to thoroughly review and discuss the clinical presentation in view of the improved diagnostics, microbiological and immunological analysis of Mp infections, with focus on the history of Mp, clinical features of disease, bacterial structure of Mp and mechanism of gliding, clinical and laboratory diagnostics, the role of lipoproteins and Toll-like receptor, CARDS toxin, subtyping of Mp isolates and genome analysis, macrolide resistance and treatment. 2021-02-11T20:26:36Z 2021-02-11T20:26:36Z 2018-02-27 16:16:45 2017 book 25662 16648714 9782889453627 https://directory.doabooks.org/handle/20.500.12854/54175 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/books/Mycoplasma_pneumoniae_Clinical_Manifestations_Microbiology_and_Immunology/1412 https://www.frontiersin.org/research-topics/3925/mycoplasma-pneumoniae-clinical-manifestations-microbiology-and-immunology Frontiers Media SA 10.3389/978-2-88945-362-7 10.3389/978-2-88945-362-7 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453627 175 open access
spellingShingle R5-920
QR1-502
Q1-390
pathogenesis
epidemiology
treatment
clinical presentation antimicrobial resistance
Mycoplasma pneumoniae
outcome
thema EDItEUR::M Medicine and Nursing
Takashi Shimizu
Ran Nir-Paz
Takeshi Saraya
Annemarie Van Rossum
Cecile Bebear
Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology
title Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology
title_full Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology
title_fullStr Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology
title_full_unstemmed Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology
title_short Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology
title_sort mycoplasma pneumoniae clinical manifestations microbiology and immunology
topic R5-920
QR1-502
Q1-390
pathogenesis
epidemiology
treatment
clinical presentation antimicrobial resistance
Mycoplasma pneumoniae
outcome
thema EDItEUR::M Medicine and Nursing
topic_facet R5-920
QR1-502
Q1-390
pathogenesis
epidemiology
treatment
clinical presentation antimicrobial resistance
Mycoplasma pneumoniae
outcome
thema EDItEUR::M Medicine and Nursing
url 25662
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