Neural and Synaptic Defects in Autism Spectrum Disorders
Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and s...
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| Үндсэн зохиолчид: | , |
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| Формат: | Online |
| Хэл сонгох: | англи |
| Хэвлэсэн: |
Frontiers Media SA
2021
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| Нөхцлүүд: | |
| Онлайн хандалт: | 19535 |
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Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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| _version_ | 1869530864814129152 |
|---|---|
| author | Hansen Wang Laurie C. Doering |
| author_browse | Hansen Wang Laurie C. Doering |
| author_facet | Hansen Wang Laurie C. Doering |
| author_sort | Hansen Wang |
| collection | Directory of Open Access Books |
| description | Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology. |
| format | Online |
| id | doab-20.500.12854ir-54467 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-544672024-04-05T17:30:26Z Neural and Synaptic Defects in Autism Spectrum Disorders Hansen Wang Laurie C. Doering RC321-571 Q1-390 MeCP2 Treatment Fragile X Syndrome Pathogenesis FMRP Autism Spectrum Disorders Pharmacology Synaptic deficits synaptic plasticity Rett Syndrome thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology. 2021-02-11T20:47:39Z 2021-02-11T20:47:39Z 2016-08-16 10:34:25 2015 book 19535 16648714 9782889196289 https://directory.doabooks.org/handle/20.500.12854/54467 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Neural_and_Synaptic_Defects_in_Autism_Spectrum_Disorders/619#nogo http://journal.frontiersin.org/researchtopic/1273/neural-and-synaptic-defects-in-autism-spectrum-disorders Frontiers Media SA 10.3389/978-2-88919-628-9 10.3389/978-2-88919-628-9 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889196289 285 open access |
| spellingShingle | RC321-571 Q1-390 MeCP2 Treatment Fragile X Syndrome Pathogenesis FMRP Autism Spectrum Disorders Pharmacology Synaptic deficits synaptic plasticity Rett Syndrome thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Hansen Wang Laurie C. Doering Neural and Synaptic Defects in Autism Spectrum Disorders |
| title | Neural and Synaptic Defects in Autism Spectrum Disorders |
| title_full | Neural and Synaptic Defects in Autism Spectrum Disorders |
| title_fullStr | Neural and Synaptic Defects in Autism Spectrum Disorders |
| title_full_unstemmed | Neural and Synaptic Defects in Autism Spectrum Disorders |
| title_short | Neural and Synaptic Defects in Autism Spectrum Disorders |
| title_sort | neural and synaptic defects in autism spectrum disorders |
| topic | RC321-571 Q1-390 MeCP2 Treatment Fragile X Syndrome Pathogenesis FMRP Autism Spectrum Disorders Pharmacology Synaptic deficits synaptic plasticity Rett Syndrome thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | RC321-571 Q1-390 MeCP2 Treatment Fragile X Syndrome Pathogenesis FMRP Autism Spectrum Disorders Pharmacology Synaptic deficits synaptic plasticity Rett Syndrome thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | 19535 |
| work_keys_str_mv | AT hansenwang neuralandsynapticdefectsinautismspectrumdisorders AT lauriecdoering neuralandsynapticdefectsinautismspectrumdisorders |