Neuroanatomy for the XXIst Century

An explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolut...

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সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Kathleen S. Rockland, Javier DeFelipe
বিন্যাস: Online
ভাষা:ইংরেজি
প্রকাশিত: Frontiers Media SA 2021
বিষয়গুলি:
অনলাইন ব্যবহার করুন:18303
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author Kathleen S. Rockland
Javier DeFelipe
author_browse Javier DeFelipe
Kathleen S. Rockland
author_facet Kathleen S. Rockland
Javier DeFelipe
author_sort Kathleen S. Rockland
collection Directory of Open Access Books
description An explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolution experimental approaches. A major goal of this e-Book is thus to highlight in one place the impressive range of available techniques, even as these are fast becoming routine. This is not meant as a technical review, however, but rather will project the technical explosion as indicative of a field now in a vibrant state of renewal. Thus, contributions will be mainly research articles using the newer techniques. A second goal is to showcase what has become the conspicuous interdisciplinary reach of the field: neuroanatomical standards and the close association of structure-function and underlying circuitry mechanisms are increasingly relevant to investigations in development, physiology, and disease. Another feature of this Research Topic is that it includes a breadth of cross-species contributions from investigators working with rodent, nonhuman primate, and human brains. This is important since most of our current knowledge of brain structure has been obtained from experimental animals. However, recent technical advances, coupled with researcher willingness to use the human tissue available, will undoubtedly lead to major advances in the near future regarding human brain mapping and connectomes. Thus, of particular interest will be the methods that can help to define general wiring principles in the brain, both structural and functional. Overall, the state of the field is: exciting.
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spelling doab-20.500.12854ir-544902024-04-05T12:35:54Z Neuroanatomy for the XXIst Century Kathleen S. Rockland Javier DeFelipe RC321-571 Q1-390 Human neuroanatomy light-sheet imaging two-photon tomography FIB/SEM fMOST synaptic weights text-mining Polarized light microscopy viral vectors thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences An explosion of new techniques with vastly improved visualization and sensitivity is leading a veritable revolution in modern neuroanatomy. Basic questions related to cell types, input localization, and connectivity are being re-visited and tackled with significantly more accurate and higher resolution experimental approaches. A major goal of this e-Book is thus to highlight in one place the impressive range of available techniques, even as these are fast becoming routine. This is not meant as a technical review, however, but rather will project the technical explosion as indicative of a field now in a vibrant state of renewal. Thus, contributions will be mainly research articles using the newer techniques. A second goal is to showcase what has become the conspicuous interdisciplinary reach of the field: neuroanatomical standards and the close association of structure-function and underlying circuitry mechanisms are increasingly relevant to investigations in development, physiology, and disease. Another feature of this Research Topic is that it includes a breadth of cross-species contributions from investigators working with rodent, nonhuman primate, and human brains. This is important since most of our current knowledge of brain structure has been obtained from experimental animals. However, recent technical advances, coupled with researcher willingness to use the human tissue available, will undoubtedly lead to major advances in the near future regarding human brain mapping and connectomes. Thus, of particular interest will be the methods that can help to define general wiring principles in the brain, both structural and functional. Overall, the state of the field is: exciting. 2021-02-11T20:48:53Z 2021-02-11T20:48:53Z 2016-01-19 14:05:46 2016 book 18303 16648714 9782889199167 https://directory.doabooks.org/handle/20.500.12854/54490 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Neuroanatomy_for_the_XXIst_Century/965#nogo http://journal.frontiersin.org/researchtopic/2893/neuroanatomy-for-the-xxist-century Frontiers Media SA 10.3389/978-2-88919-916-7 10.3389/978-2-88919-916-7 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889199167 199 open access
spellingShingle RC321-571
Q1-390
Human neuroanatomy
light-sheet imaging
two-photon tomography
FIB/SEM
fMOST
synaptic weights
text-mining
Polarized light microscopy
viral vectors
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Kathleen S. Rockland
Javier DeFelipe
Neuroanatomy for the XXIst Century
title Neuroanatomy for the XXIst Century
title_full Neuroanatomy for the XXIst Century
title_fullStr Neuroanatomy for the XXIst Century
title_full_unstemmed Neuroanatomy for the XXIst Century
title_short Neuroanatomy for the XXIst Century
title_sort neuroanatomy for the xxist century
topic RC321-571
Q1-390
Human neuroanatomy
light-sheet imaging
two-photon tomography
FIB/SEM
fMOST
synaptic weights
text-mining
Polarized light microscopy
viral vectors
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet RC321-571
Q1-390
Human neuroanatomy
light-sheet imaging
two-photon tomography
FIB/SEM
fMOST
synaptic weights
text-mining
Polarized light microscopy
viral vectors
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url 18303
work_keys_str_mv AT kathleensrockland neuroanatomyforthexxistcentury
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