Neuroinflammation and Behaviour

The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cog...

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Main Authors: Deborah M. Hodgson, Luba Sominsky, Adam K. Walker
Format: Online
Jezik:angleščina
Izdano: Frontiers Media SA 2021
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author Deborah M. Hodgson
Luba Sominsky
Adam K. Walker
author_browse Adam K. Walker
Deborah M. Hodgson
Luba Sominsky
author_facet Deborah M. Hodgson
Luba Sominsky
Adam K. Walker
author_sort Deborah M. Hodgson
collection Directory of Open Access Books
description The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesity, infection and autoimmune disorders. Similarly, psychological states can alter regulation of the immune system. This has been most extensively studied in the context of stress and immune function. Understanding the underlying mechanisms that lead to the onset of inflammation-induced neuropathology and stress-induced immune suppression will contribute to the development of novel and effective treatment strategies for both the disease and its neurological side effects. In this research topic we explored the relationship between the immune system and the brain throughout life. We include both original research and review papers from animal, clinical and molecular perspectives.
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spelling doab-20.500.12854ir-545062024-04-05T12:35:18Z Neuroinflammation and Behaviour Deborah M. Hodgson Luba Sominsky Adam K. Walker RC321-571 Q1-390 neuroimmune Obesity neuroendocrine proinflammatory Aging Neuroinflammation Depression Mood Disorders Microglia Perinatal programming thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesity, infection and autoimmune disorders. Similarly, psychological states can alter regulation of the immune system. This has been most extensively studied in the context of stress and immune function. Understanding the underlying mechanisms that lead to the onset of inflammation-induced neuropathology and stress-induced immune suppression will contribute to the development of novel and effective treatment strategies for both the disease and its neurological side effects. In this research topic we explored the relationship between the immune system and the brain throughout life. We include both original research and review papers from animal, clinical and molecular perspectives. 2021-02-11T20:49:50Z 2021-02-11T20:49:50Z 2016-08-16 10:34:25 2015 book 19510 16648714 9782889196029 https://directory.doabooks.org/handle/20.500.12854/54506 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Neuroinflammation_and_Behaviour/643 http://journal.frontiersin.org/researchtopic/2634/neuroinflammation-and-behaviour Frontiers Media SA 10.3389/978-2-88919-602-9 10.3389/978-2-88919-602-9 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889196029 181 open access
spellingShingle RC321-571
Q1-390
neuroimmune
Obesity
neuroendocrine
proinflammatory
Aging
Neuroinflammation
Depression
Mood Disorders
Microglia
Perinatal programming
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Deborah M. Hodgson
Luba Sominsky
Adam K. Walker
Neuroinflammation and Behaviour
title Neuroinflammation and Behaviour
title_full Neuroinflammation and Behaviour
title_fullStr Neuroinflammation and Behaviour
title_full_unstemmed Neuroinflammation and Behaviour
title_short Neuroinflammation and Behaviour
title_sort neuroinflammation and behaviour
topic RC321-571
Q1-390
neuroimmune
Obesity
neuroendocrine
proinflammatory
Aging
Neuroinflammation
Depression
Mood Disorders
Microglia
Perinatal programming
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet RC321-571
Q1-390
neuroimmune
Obesity
neuroendocrine
proinflammatory
Aging
Neuroinflammation
Depression
Mood Disorders
Microglia
Perinatal programming
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url 19510
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