NK Cell Subsets in Health and Disease: New Developments

Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory...

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Ngā kaituhi matua: Emanuela Marcenaro, Luigi D. Notarangelo, Jordan S. Orange, Eric Vivier
Hōputu: Online
Reo:Ingarihi
I whakaputaina: Frontiers Media SA 2021
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Urunga tuihono:25650
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author Emanuela Marcenaro
Luigi D. Notarangelo
Jordan S. Orange
Eric Vivier
author_browse Emanuela Marcenaro
Eric Vivier
Jordan S. Orange
Luigi D. Notarangelo
author_facet Emanuela Marcenaro
Luigi D. Notarangelo
Jordan S. Orange
Eric Vivier
author_sort Emanuela Marcenaro
collection Directory of Open Access Books
description Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
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spelling doab-20.500.12854ir-546912024-03-31T13:09:48Z NK Cell Subsets in Health and Disease: New Developments Emanuela Marcenaro Luigi D. Notarangelo Jordan S. Orange Eric Vivier R5-920 RC581-607 ILCs inflammation NK cell subsets immunotherapy anti-viral responses anti-tumor responses immune checkpoints thema EDItEUR::M Medicine and Nursing Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology. 2021-02-11T21:02:05Z 2021-02-11T21:02:05Z 2018-02-27 16:16:45 2017 book 25650 16648714 9782889453504 https://directory.doabooks.org/handle/20.500.12854/54691 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/books/NK_Cell_Subsets_in_Health_and_Disease_New_Developments/1394#nogo https://www.frontiersin.org/research-topics/4350/nk-cell-subsets-in-health-and-disease-new-developments Frontiers Media SA 10.3389/978-2-88945-350-4 10.3389/978-2-88945-350-4 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453504 243 open access
spellingShingle R5-920
RC581-607
ILCs
inflammation
NK cell subsets
immunotherapy
anti-viral responses
anti-tumor responses
immune checkpoints
thema EDItEUR::M Medicine and Nursing
Emanuela Marcenaro
Luigi D. Notarangelo
Jordan S. Orange
Eric Vivier
NK Cell Subsets in Health and Disease: New Developments
title NK Cell Subsets in Health and Disease: New Developments
title_full NK Cell Subsets in Health and Disease: New Developments
title_fullStr NK Cell Subsets in Health and Disease: New Developments
title_full_unstemmed NK Cell Subsets in Health and Disease: New Developments
title_short NK Cell Subsets in Health and Disease: New Developments
title_sort nk cell subsets in health and disease new developments
topic R5-920
RC581-607
ILCs
inflammation
NK cell subsets
immunotherapy
anti-viral responses
anti-tumor responses
immune checkpoints
thema EDItEUR::M Medicine and Nursing
topic_facet R5-920
RC581-607
ILCs
inflammation
NK cell subsets
immunotherapy
anti-viral responses
anti-tumor responses
immune checkpoints
thema EDItEUR::M Medicine and Nursing
url 25650
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