NLR-protein functions in immunity

The Nod-like receptor (NLR) family of proteins are evolutionary conserved molecules that in plants and mammals have been implicated in innate immune sensing of microbes and infection-associated physiological changes, contributing to immune protection of the challenged host organism through the instr...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Jorg H. Fritz, Thomas A. Kufer
বিন্যাস: Online
ভাষা:ইংরেজি
প্রকাশিত: Frontiers Media SA 2021
বিষয়গুলি:
অনলাইন ব্যবহার করুন:19528
ট্যাগগুলো: ট্যাগ যুক্ত করুন
কোনো ট্যাগ নেই, প্রথমজন হিসাবে ট্যাগ করুন!
_version_ 1869531238825459712
author Jorg H. Fritz
Thomas A. Kufer
author_browse Jorg H. Fritz
Thomas A. Kufer
author_facet Jorg H. Fritz
Thomas A. Kufer
author_sort Jorg H. Fritz
collection Directory of Open Access Books
description The Nod-like receptor (NLR) family of proteins are evolutionary conserved molecules that in plants and mammals have been implicated in innate immune sensing of microbes and infection-associated physiological changes, contributing to immune protection of the challenged host organism through the instruction of inflammatory responses, antimicrobial defense and adaptive immunity. Recent data however suggests that the biological roles of NLR go beyond the function of classical pattern recognition molecules (PRM) as they have been implicated in essential cellular processes including autophagy, apoptosis, modification of signal transduction and gene transcription as well as reproductive biology. In this research topic, we aim to provide a comprehensive state-of the art overview of the emerging functions of NLR in plant and mammalian immunity, cell biology and reproductive biology. Potential topics may include, but are not limited to the following areas: • Functions of NLRs as PRMs in infection • Cross-talk of NLRs with other PRMs • Signal transduction pathways of NLRs • New functions of NLRs other than pattern recognition • Structural aspects of NLR activation • Mechanisms of NLRs in cell biological processes • Aspects of NLRs in reproductive biology • Functions of NLRs in plant immune responses
format Online
id doab-20.500.12854ir-54693
institution Directory of Open Access Books
language eng
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher Frontiers Media SA
publisherStr Frontiers Media SA
record_format ojs
spelling doab-20.500.12854ir-546932024-03-31T13:10:19Z NLR-protein functions in immunity Jorg H. Fritz Thomas A. Kufer R5-920 RC581-607 Adaptive Immunity PAMP pathogens MAMP innate immunity Bacteria Sensing virus LRR DAMP thema EDItEUR::M Medicine and Nursing The Nod-like receptor (NLR) family of proteins are evolutionary conserved molecules that in plants and mammals have been implicated in innate immune sensing of microbes and infection-associated physiological changes, contributing to immune protection of the challenged host organism through the instruction of inflammatory responses, antimicrobial defense and adaptive immunity. Recent data however suggests that the biological roles of NLR go beyond the function of classical pattern recognition molecules (PRM) as they have been implicated in essential cellular processes including autophagy, apoptosis, modification of signal transduction and gene transcription as well as reproductive biology. In this research topic, we aim to provide a comprehensive state-of the art overview of the emerging functions of NLR in plant and mammalian immunity, cell biology and reproductive biology. Potential topics may include, but are not limited to the following areas: • Functions of NLRs as PRMs in infection • Cross-talk of NLRs with other PRMs • Signal transduction pathways of NLRs • New functions of NLRs other than pattern recognition • Structural aspects of NLR activation • Mechanisms of NLRs in cell biological processes • Aspects of NLRs in reproductive biology • Functions of NLRs in plant immune responses 2021-02-11T21:02:13Z 2021-02-11T21:02:13Z 2016-08-16 10:34:25 2015 book 19528 16648714 9782889196210 https://directory.doabooks.org/handle/20.500.12854/54693 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/NLR-protein_functions_in_immunity/623 http://journal.frontiersin.org/researchtopic/1165/nlr-protein-functions-in-immunity Frontiers Media SA 10.3389/978-2-88919-621-0 10.3389/978-2-88919-621-0 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889196210 220 open access
spellingShingle R5-920
RC581-607
Adaptive Immunity
PAMP
pathogens
MAMP
innate immunity
Bacteria
Sensing
virus
LRR
DAMP
thema EDItEUR::M Medicine and Nursing
Jorg H. Fritz
Thomas A. Kufer
NLR-protein functions in immunity
title NLR-protein functions in immunity
title_full NLR-protein functions in immunity
title_fullStr NLR-protein functions in immunity
title_full_unstemmed NLR-protein functions in immunity
title_short NLR-protein functions in immunity
title_sort nlr protein functions in immunity
topic R5-920
RC581-607
Adaptive Immunity
PAMP
pathogens
MAMP
innate immunity
Bacteria
Sensing
virus
LRR
DAMP
thema EDItEUR::M Medicine and Nursing
topic_facet R5-920
RC581-607
Adaptive Immunity
PAMP
pathogens
MAMP
innate immunity
Bacteria
Sensing
virus
LRR
DAMP
thema EDItEUR::M Medicine and Nursing
url 19528
work_keys_str_mv AT jorghfritz nlrproteinfunctionsinimmunity
AT thomasakufer nlrproteinfunctionsinimmunity