Novel Molecular Approaches to Target Microbial Virulence
Microbial infections still represent one of the major causes of mortality and morbidity worldwide. Irrational usage of antimicrobials has lead to increased resistance, causing clinical, social and economical disabilities. Therefore, one of the major challenges of scientists is to develop novel alter...
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| Main Authors: | , |
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| Formato: | Online |
| Idioma: | inglés |
| Publicado: |
De Gruyter
2021
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| Subjects: | |
| Acceso en liña: | 17962 |
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| _version_ | 1869523599106244608 |
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| author | Holban, Alina Maria Grumezescu, Alexandru Mihai |
| author_browse | Grumezescu, Alexandru Mihai Holban, Alina Maria |
| author_facet | Holban, Alina Maria Grumezescu, Alexandru Mihai |
| author_sort | Holban, Alina Maria |
| collection | Directory of Open Access Books |
| description | Microbial infections still represent one of the major causes of mortality and morbidity worldwide. Irrational usage of antimicrobials has lead to increased resistance, causing clinical, social and economical disabilities. Therefore, one of the major challenges of scientists is to develop novel alternative methods to handle infections and reduce resistance and other side effects produced by the actual therapies. The aim of this book is to offer a perspective on novel approaches to handle infections by using naturally-derived products in order to modulate the virulence of pathogens, without the risk of developing resistance. We intend to highlight the utility of microbial, vegetal and animal–derived compounds with potential antimicrobial activity by exploiting their effect on microbial virulence. Furthermore, this book aims to reveal the potential to assimilate recent bio-technological findings, like the usage of nanotechnology as efficient shuttles for stabilizing, improved targeting and the controlled release of natural products in order to efficiently fight infections. |
| format | Online |
| id | doab-20.500.12854ir-54879 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | De Gruyter |
| publisherStr | De Gruyter |
| record_format | ojs |
| spelling | doab-20.500.12854ir-548792024-04-11T15:10:47Z Novel Molecular Approaches to Target Microbial Virulence Holban, Alina Maria Grumezescu, Alexandru Mihai TP248.13-248.65 QR1-502 RC109-216 virulence molecular modulation antimicrobial therapy drug delivery nanoshuttles thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology Microbial infections still represent one of the major causes of mortality and morbidity worldwide. Irrational usage of antimicrobials has lead to increased resistance, causing clinical, social and economical disabilities. Therefore, one of the major challenges of scientists is to develop novel alternative methods to handle infections and reduce resistance and other side effects produced by the actual therapies. The aim of this book is to offer a perspective on novel approaches to handle infections by using naturally-derived products in order to modulate the virulence of pathogens, without the risk of developing resistance. We intend to highlight the utility of microbial, vegetal and animal–derived compounds with potential antimicrobial activity by exploiting their effect on microbial virulence. Furthermore, this book aims to reveal the potential to assimilate recent bio-technological findings, like the usage of nanotechnology as efficient shuttles for stabilizing, improved targeting and the controlled release of natural products in order to efficiently fight infections. 2021-02-11T21:17:26Z 2021-02-11T21:17:26Z 2016-01-06 13:06:10 2015 book 17962 9783110449501 9783110449617 https://directory.doabooks.org/handle/20.500.12854/54879 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://doi.org/10.1515/9783110449501 De Gruyter 10.1515/9783110449501 10.1515/9783110449501 af2fbfcc-ee87-43d8-a035-afb9d7eef6a5 9783110449501 9783110449617 87 open access |
| spellingShingle | TP248.13-248.65 QR1-502 RC109-216 virulence molecular modulation antimicrobial therapy drug delivery nanoshuttles thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology Holban, Alina Maria Grumezescu, Alexandru Mihai Novel Molecular Approaches to Target Microbial Virulence |
| title | Novel Molecular Approaches to Target Microbial Virulence |
| title_full | Novel Molecular Approaches to Target Microbial Virulence |
| title_fullStr | Novel Molecular Approaches to Target Microbial Virulence |
| title_full_unstemmed | Novel Molecular Approaches to Target Microbial Virulence |
| title_short | Novel Molecular Approaches to Target Microbial Virulence |
| title_sort | novel molecular approaches to target microbial virulence |
| topic | TP248.13-248.65 QR1-502 RC109-216 virulence molecular modulation antimicrobial therapy drug delivery nanoshuttles thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology |
| topic_facet | TP248.13-248.65 QR1-502 RC109-216 virulence molecular modulation antimicrobial therapy drug delivery nanoshuttles thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology |
| url | 17962 |
| work_keys_str_mv | AT holbanalinamaria novelmolecularapproachestotargetmicrobialvirulence AT grumezescualexandrumihai novelmolecularapproachestotargetmicrobialvirulence |