Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials
Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynam...
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| Médium: | Online |
| Jazyk: | angličtina |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Témata: | |
| On-line přístup: | 42464 |
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| _version_ | 1869520006356664320 |
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| author | Afonin, Kirill |
| author_browse | Afonin, Kirill |
| author_facet | Afonin, Kirill |
| author_sort | Afonin, Kirill |
| collection | Directory of Open Access Books |
| description | Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications. |
| format | Online |
| id | doab-20.500.12854ir-54903 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-549032024-04-05T12:32:27Z Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials Afonin, Kirill QH301-705.5 Q1-390 cotranscriptional folding n/a RNA conditionally activated i-motif DNA spinal cord tumor fluorescence dynamic stability functional RNA ribozyme biological media RNA aptamers gene therapy biosensors viral vector ganciclovir RNA self-assembly RNA nanoparticle gene delivery riboswitch non-viral gene delivery NANPs silver nanoclusters small-angle neutron scattering contrast variation aptamers RNA logic fluorogenic RNA glioblastoma multiforme RNA interference nucleic acid nanoparticles immunostimulation aggregation small-angle X-ray scattering non-viral vector light-up aptamer nucleic acid therapeutic live-cell imaging DNA nanotechnology nucleic acid computing nanopores structural characterization siRNA suicide gene therapy nucleic acid nanoparticle cytosine rich sequences RNA nanotechnology logic gates serum conditional activation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications. 2021-02-11T21:18:51Z 2021-02-11T21:18:51Z 2019-12-09 11:49:15 2019 book 42464 9783039212590 9783039212606 https://directory.doabooks.org/handle/20.500.12854/54903 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1473 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03921-260-6 10.3390/books978-3-03921-260-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039212590 9783039212606 186 open access |
| spellingShingle | QH301-705.5 Q1-390 cotranscriptional folding n/a RNA conditionally activated i-motif DNA spinal cord tumor fluorescence dynamic stability functional RNA ribozyme biological media RNA aptamers gene therapy biosensors viral vector ganciclovir RNA self-assembly RNA nanoparticle gene delivery riboswitch non-viral gene delivery NANPs silver nanoclusters small-angle neutron scattering contrast variation aptamers RNA logic fluorogenic RNA glioblastoma multiforme RNA interference nucleic acid nanoparticles immunostimulation aggregation small-angle X-ray scattering non-viral vector light-up aptamer nucleic acid therapeutic live-cell imaging DNA nanotechnology nucleic acid computing nanopores structural characterization siRNA suicide gene therapy nucleic acid nanoparticle cytosine rich sequences RNA nanotechnology logic gates serum conditional activation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Afonin, Kirill Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials |
| title | Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials |
| title_full | Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials |
| title_fullStr | Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials |
| title_full_unstemmed | Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials |
| title_short | Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials |
| title_sort | nucleic acid architectures for therapeutics diagnostics devices and materials |
| topic | QH301-705.5 Q1-390 cotranscriptional folding n/a RNA conditionally activated i-motif DNA spinal cord tumor fluorescence dynamic stability functional RNA ribozyme biological media RNA aptamers gene therapy biosensors viral vector ganciclovir RNA self-assembly RNA nanoparticle gene delivery riboswitch non-viral gene delivery NANPs silver nanoclusters small-angle neutron scattering contrast variation aptamers RNA logic fluorogenic RNA glioblastoma multiforme RNA interference nucleic acid nanoparticles immunostimulation aggregation small-angle X-ray scattering non-viral vector light-up aptamer nucleic acid therapeutic live-cell imaging DNA nanotechnology nucleic acid computing nanopores structural characterization siRNA suicide gene therapy nucleic acid nanoparticle cytosine rich sequences RNA nanotechnology logic gates serum conditional activation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 Q1-390 cotranscriptional folding n/a RNA conditionally activated i-motif DNA spinal cord tumor fluorescence dynamic stability functional RNA ribozyme biological media RNA aptamers gene therapy biosensors viral vector ganciclovir RNA self-assembly RNA nanoparticle gene delivery riboswitch non-viral gene delivery NANPs silver nanoclusters small-angle neutron scattering contrast variation aptamers RNA logic fluorogenic RNA glioblastoma multiforme RNA interference nucleic acid nanoparticles immunostimulation aggregation small-angle X-ray scattering non-viral vector light-up aptamer nucleic acid therapeutic live-cell imaging DNA nanotechnology nucleic acid computing nanopores structural characterization siRNA suicide gene therapy nucleic acid nanoparticle cytosine rich sequences RNA nanotechnology logic gates serum conditional activation thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 42464 |
| work_keys_str_mv | AT afoninkirill nucleicacidarchitecturesfortherapeuticsdiagnosticsdevicesandmaterials |