Organogenesis From Development to Disease
During embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slig...
Zapisane w:
| Główni autorzy: | , , |
|---|---|
| Format: | Online |
| Język: | angielski |
| Wydane: |
Frontiers Media SA
2021
|
| Hasła przedmiotowe: | |
| Dostęp online: | 29696 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|
| _version_ | 1869528232070479872 |
|---|---|
| author | Misty Good Seppo Vainio Sunder Sims-Lucas |
| author_browse | Misty Good Seppo Vainio Sunder Sims-Lucas |
| author_facet | Misty Good Seppo Vainio Sunder Sims-Lucas |
| author_sort | Misty Good |
| collection | Directory of Open Access Books |
| description | During embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slight malformations of the organs can cause developmental reprogramming and increase the likelihood of adult onset diseases. The use of experimental animals with genetic mutations that mimic many human conditions has lead to significant scientific advancement of these complex and multifaceted diseases. Furthermore, the utilization of organ culture systems has made for profound insights into the formation of organs. Over recent years, the technology related to molecular profiling and imaging of developing organs has dramatically improved, leading to the identification of subtle genetic and phenotypic alterations. This research topic will focus on the area of organ formation and modeling of human developmental diseases. |
| format | Online |
| id | doab-20.500.12854ir-55410 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-554102024-04-05T12:33:25Z Organogenesis From Development to Disease Misty Good Seppo Vainio Sunder Sims-Lucas QH301-705.5 Q1-390 Disease Models kidney development Bladder innervation Animal Bowel disease Inflammation Developmental Biology Diabetes Mellitus Organogenesis Type 1 bone mineralization thema EDItEUR::P Mathematics and Science::PS Biology, life sciences During embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slight malformations of the organs can cause developmental reprogramming and increase the likelihood of adult onset diseases. The use of experimental animals with genetic mutations that mimic many human conditions has lead to significant scientific advancement of these complex and multifaceted diseases. Furthermore, the utilization of organ culture systems has made for profound insights into the formation of organs. Over recent years, the technology related to molecular profiling and imaging of developing organs has dramatically improved, leading to the identification of subtle genetic and phenotypic alterations. This research topic will focus on the area of organ formation and modeling of human developmental diseases. 2021-02-11T21:52:40Z 2021-02-11T21:52:40Z 2018-11-16 17:27:07 2017 book 29696 16648714 9782889453184 https://directory.doabooks.org/handle/20.500.12854/55410 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/3607/organogenesis-from-development-to-disease Frontiers Media SA 10.3389/978-2-88945-318-4 10.3389/978-2-88945-318-4 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453184 110 open access |
| spellingShingle | QH301-705.5 Q1-390 Disease Models kidney development Bladder innervation Animal Bowel disease Inflammation Developmental Biology Diabetes Mellitus Organogenesis Type 1 bone mineralization thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Misty Good Seppo Vainio Sunder Sims-Lucas Organogenesis From Development to Disease |
| title | Organogenesis From Development to Disease |
| title_full | Organogenesis From Development to Disease |
| title_fullStr | Organogenesis From Development to Disease |
| title_full_unstemmed | Organogenesis From Development to Disease |
| title_short | Organogenesis From Development to Disease |
| title_sort | organogenesis from development to disease |
| topic | QH301-705.5 Q1-390 Disease Models kidney development Bladder innervation Animal Bowel disease Inflammation Developmental Biology Diabetes Mellitus Organogenesis Type 1 bone mineralization thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 Q1-390 Disease Models kidney development Bladder innervation Animal Bowel disease Inflammation Developmental Biology Diabetes Mellitus Organogenesis Type 1 bone mineralization thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 29696 |
| work_keys_str_mv | AT mistygood organogenesisfromdevelopmenttodisease AT seppovainio organogenesisfromdevelopmenttodisease AT sundersimslucas organogenesisfromdevelopmenttodisease |