Organophosphorus Chemistry 2018
Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important starting materials or intermediates in syntheses. Let...
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| Aineistotyyppi: | Online |
| Kieli: | englanti |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Linkit: | 44773 |
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| _version_ | 1869514736164405248 |
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| author | Keglevich, György |
| author_browse | Keglevich, György |
| author_facet | Keglevich, György |
| author_sort | Keglevich, György |
| collection | Directory of Open Access Books |
| description | Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important starting materials or intermediates in syntheses. Let us mention the Wittig reaction and the related transformations, the Arbuzov- and the Pudovik reactions, the Kabachnik–Fields condensation, the Hirao reaction, the Mitsunobu reaction, etc. Other reactions, e.g., homogeneous catalytic transformations or C-C coupling reactions involve P-ligands in transition metal (Pt, Pd, etc.) complex catalysts. The synthesis of chiral organophosphorus compounds means a continuous challenge. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective organophosphorus transformations. P-heterocyclic compounds, including aromatic and bridged derivatives, P-functionalized macrocycles, dendrimers and low coordinated P-fragments, are also of interest. An important segment of organophosphorus chemistry is the pool of biologically-active compounds that are searched and used as drugs, or as plant-protecting agents. The natural analogue of P-compounds may also be mentioned. Many new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described, which may find application on a broad scale. Phase transfer catalysis, ionic liquids and detergents also have connections to phosphorus chemistry. Green chemical aspects of organophosphorus chemistry (e.g., microwave-assisted syntheses, solvent-free accomplishments, optimizations, and atom-efficient syntheses) represent a dynamically developing field. Last, but not least, theoretical approaches and computational chemistry are also a strong sub-discipline within organophosphorus chemistry. |
| format | Online |
| id | doab-20.500.12854ir-55412 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-554122024-04-05T12:38:43Z Organophosphorus Chemistry 2018 Keglevich, György QD1-999 QD241-441 Q1-390 synergy 1-(acylamino)alkylphosphonic acids hydrolytic deacylation chiral phosphines organophosphorus chemistry alcoholysis electrophilic substitution NORPHOS DFT diphosphines dry eye syndrome cyclo-P5 O-derivatization triple-decker phosphorylation molybdenum NMR-controlled titration mechanochemistry N-acyliminium cation stability constants Pudovik reaction phosphonocarboxylic acids 1 aminophosphonic acids allylic alkylation diquafosol silver Diels-Alder reaction QTAIM dissociation constants weakly coordinating substitution phosphonium salts amino acids continuous flow reactor DFT calculations metallacycle 31P NMR spectra of intermediates dinucleotides N-acylimine copper microwave 1-aminoalkylphosphonic acids phosphonic acids bis(phosphane) palladium complex denufosol oxidation C-H bond activation asymmetric catalysis dynamic and specific NMR parameters electronic parameters dialkyl H-phosphonates ?-hydroxyphosphonate transesterification polycyclic compounds stereoselective synthesis rearrangement hydrolysis ?-amidoalkylating agents 3-azaphospholes thema EDItEUR::P Mathematics and Science::PN Chemistry Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important starting materials or intermediates in syntheses. Let us mention the Wittig reaction and the related transformations, the Arbuzov- and the Pudovik reactions, the Kabachnik–Fields condensation, the Hirao reaction, the Mitsunobu reaction, etc. Other reactions, e.g., homogeneous catalytic transformations or C-C coupling reactions involve P-ligands in transition metal (Pt, Pd, etc.) complex catalysts. The synthesis of chiral organophosphorus compounds means a continuous challenge. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective organophosphorus transformations. P-heterocyclic compounds, including aromatic and bridged derivatives, P-functionalized macrocycles, dendrimers and low coordinated P-fragments, are also of interest. An important segment of organophosphorus chemistry is the pool of biologically-active compounds that are searched and used as drugs, or as plant-protecting agents. The natural analogue of P-compounds may also be mentioned. Many new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described, which may find application on a broad scale. Phase transfer catalysis, ionic liquids and detergents also have connections to phosphorus chemistry. Green chemical aspects of organophosphorus chemistry (e.g., microwave-assisted syntheses, solvent-free accomplishments, optimizations, and atom-efficient syntheses) represent a dynamically developing field. Last, but not least, theoretical approaches and computational chemistry are also a strong sub-discipline within organophosphorus chemistry. 2021-02-11T21:52:49Z 2021-02-11T21:52:49Z 2020-04-07 23:07:08 2020 book 44773 9783039282364 9783039282371 https://directory.doabooks.org/handle/20.500.12854/55412 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/2050 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03928-237-1 10.3390/books978-3-03928-237-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039282364 9783039282371 601 open access |
| spellingShingle | QD1-999 QD241-441 Q1-390 synergy 1-(acylamino)alkylphosphonic acids hydrolytic deacylation chiral phosphines organophosphorus chemistry alcoholysis electrophilic substitution NORPHOS DFT diphosphines dry eye syndrome cyclo-P5 O-derivatization triple-decker phosphorylation molybdenum NMR-controlled titration mechanochemistry N-acyliminium cation stability constants Pudovik reaction phosphonocarboxylic acids 1 aminophosphonic acids allylic alkylation diquafosol silver Diels-Alder reaction QTAIM dissociation constants weakly coordinating substitution phosphonium salts amino acids continuous flow reactor DFT calculations metallacycle 31P NMR spectra of intermediates dinucleotides N-acylimine copper microwave 1-aminoalkylphosphonic acids phosphonic acids bis(phosphane) palladium complex denufosol oxidation C-H bond activation asymmetric catalysis dynamic and specific NMR parameters electronic parameters dialkyl H-phosphonates ?-hydroxyphosphonate transesterification polycyclic compounds stereoselective synthesis rearrangement hydrolysis ?-amidoalkylating agents 3-azaphospholes thema EDItEUR::P Mathematics and Science::PN Chemistry Keglevich, György Organophosphorus Chemistry 2018 |
| title | Organophosphorus Chemistry 2018 |
| title_full | Organophosphorus Chemistry 2018 |
| title_fullStr | Organophosphorus Chemistry 2018 |
| title_full_unstemmed | Organophosphorus Chemistry 2018 |
| title_short | Organophosphorus Chemistry 2018 |
| title_sort | organophosphorus chemistry 2018 |
| topic | QD1-999 QD241-441 Q1-390 synergy 1-(acylamino)alkylphosphonic acids hydrolytic deacylation chiral phosphines organophosphorus chemistry alcoholysis electrophilic substitution NORPHOS DFT diphosphines dry eye syndrome cyclo-P5 O-derivatization triple-decker phosphorylation molybdenum NMR-controlled titration mechanochemistry N-acyliminium cation stability constants Pudovik reaction phosphonocarboxylic acids 1 aminophosphonic acids allylic alkylation diquafosol silver Diels-Alder reaction QTAIM dissociation constants weakly coordinating substitution phosphonium salts amino acids continuous flow reactor DFT calculations metallacycle 31P NMR spectra of intermediates dinucleotides N-acylimine copper microwave 1-aminoalkylphosphonic acids phosphonic acids bis(phosphane) palladium complex denufosol oxidation C-H bond activation asymmetric catalysis dynamic and specific NMR parameters electronic parameters dialkyl H-phosphonates ?-hydroxyphosphonate transesterification polycyclic compounds stereoselective synthesis rearrangement hydrolysis ?-amidoalkylating agents 3-azaphospholes thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | QD1-999 QD241-441 Q1-390 synergy 1-(acylamino)alkylphosphonic acids hydrolytic deacylation chiral phosphines organophosphorus chemistry alcoholysis electrophilic substitution NORPHOS DFT diphosphines dry eye syndrome cyclo-P5 O-derivatization triple-decker phosphorylation molybdenum NMR-controlled titration mechanochemistry N-acyliminium cation stability constants Pudovik reaction phosphonocarboxylic acids 1 aminophosphonic acids allylic alkylation diquafosol silver Diels-Alder reaction QTAIM dissociation constants weakly coordinating substitution phosphonium salts amino acids continuous flow reactor DFT calculations metallacycle 31P NMR spectra of intermediates dinucleotides N-acylimine copper microwave 1-aminoalkylphosphonic acids phosphonic acids bis(phosphane) palladium complex denufosol oxidation C-H bond activation asymmetric catalysis dynamic and specific NMR parameters electronic parameters dialkyl H-phosphonates ?-hydroxyphosphonate transesterification polycyclic compounds stereoselective synthesis rearrangement hydrolysis ?-amidoalkylating agents 3-azaphospholes thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | 44773 |
| work_keys_str_mv | AT keglevichgyorgy organophosphoruschemistry2018 |