Organs-on-chips
Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within mi...
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| Main Authors: | , |
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| Formato: | Online |
| Idioma: | inglês |
| Publicado em: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Assuntos: | |
| Acesso em linha: | 46127 |
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| _version_ | 1869516031304663040 |
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| author | Tung, Yi-Chung Torisawa, Yu-suke |
| author_browse | Torisawa, Yu-suke Tung, Yi-Chung |
| author_facet | Tung, Yi-Chung Torisawa, Yu-suke |
| author_sort | Tung, Yi-Chung |
| collection | Directory of Open Access Books |
| description | Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices. |
| format | Online |
| id | doab-20.500.12854ir-55413 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-554132024-04-11T15:11:26Z Organs-on-chips Tung, Yi-Chung Torisawa, Yu-suke TA1-2040 T1-995 n/a tissue engineering microfluidic device ischemia/reperfusion injury syringe pump liver-on-a-chip vacuum chuck epithelial–endothelial interface vessel branching organs-on-chips nanogrooves passive delivery functional neuron imaging organ-on-a-chip lung epithelial cell MEMS drug absorption strain 3D cell culture system mechanical cue multi-culture angiogenesis high-throughput screening fluoroelastomer membranes cell culture paracellular/transcellular transport beating force microfabrication drug hepatotoxicity biomimetic oxidation compression microfluidics surfactant protein PDMS neuronal cell networks neuronal guidance trans-epithelial electrical resistance spheroid array organ-on-a-chip (OOC) biomechanics cell organ-on-chips organ-on-chip stretch shear stress shear flow image-based screening drug metabolism vascularization human induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM) stress barrier permeability bio-mechanical property cardiac 3D tissue endothelial cell activation organoid silicon lattice light-sheet microscopy integrated pump SH-SY5Y cells thrombolysis 3D cell culture neuronal cells drug efficacy vascularized tumor model thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices. 2021-02-11T21:52:55Z 2021-02-11T21:52:55Z 2020-06-09 16:38:57 2020 book 46127 9783039289172 9783039289189 https://directory.doabooks.org/handle/20.500.12854/55413 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/2321 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03928-918-9 10.3390/books978-3-03928-918-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039289172 9783039289189 262 open access |
| spellingShingle | TA1-2040 T1-995 n/a tissue engineering microfluidic device ischemia/reperfusion injury syringe pump liver-on-a-chip vacuum chuck epithelial–endothelial interface vessel branching organs-on-chips nanogrooves passive delivery functional neuron imaging organ-on-a-chip lung epithelial cell MEMS drug absorption strain 3D cell culture system mechanical cue multi-culture angiogenesis high-throughput screening fluoroelastomer membranes cell culture paracellular/transcellular transport beating force microfabrication drug hepatotoxicity biomimetic oxidation compression microfluidics surfactant protein PDMS neuronal cell networks neuronal guidance trans-epithelial electrical resistance spheroid array organ-on-a-chip (OOC) biomechanics cell organ-on-chips organ-on-chip stretch shear stress shear flow image-based screening drug metabolism vascularization human induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM) stress barrier permeability bio-mechanical property cardiac 3D tissue endothelial cell activation organoid silicon lattice light-sheet microscopy integrated pump SH-SY5Y cells thrombolysis 3D cell culture neuronal cells drug efficacy vascularized tumor model thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology Tung, Yi-Chung Torisawa, Yu-suke Organs-on-chips |
| title | Organs-on-chips |
| title_full | Organs-on-chips |
| title_fullStr | Organs-on-chips |
| title_full_unstemmed | Organs-on-chips |
| title_short | Organs-on-chips |
| title_sort | organs on chips |
| topic | TA1-2040 T1-995 n/a tissue engineering microfluidic device ischemia/reperfusion injury syringe pump liver-on-a-chip vacuum chuck epithelial–endothelial interface vessel branching organs-on-chips nanogrooves passive delivery functional neuron imaging organ-on-a-chip lung epithelial cell MEMS drug absorption strain 3D cell culture system mechanical cue multi-culture angiogenesis high-throughput screening fluoroelastomer membranes cell culture paracellular/transcellular transport beating force microfabrication drug hepatotoxicity biomimetic oxidation compression microfluidics surfactant protein PDMS neuronal cell networks neuronal guidance trans-epithelial electrical resistance spheroid array organ-on-a-chip (OOC) biomechanics cell organ-on-chips organ-on-chip stretch shear stress shear flow image-based screening drug metabolism vascularization human induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM) stress barrier permeability bio-mechanical property cardiac 3D tissue endothelial cell activation organoid silicon lattice light-sheet microscopy integrated pump SH-SY5Y cells thrombolysis 3D cell culture neuronal cells drug efficacy vascularized tumor model thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology |
| topic_facet | TA1-2040 T1-995 n/a tissue engineering microfluidic device ischemia/reperfusion injury syringe pump liver-on-a-chip vacuum chuck epithelial–endothelial interface vessel branching organs-on-chips nanogrooves passive delivery functional neuron imaging organ-on-a-chip lung epithelial cell MEMS drug absorption strain 3D cell culture system mechanical cue multi-culture angiogenesis high-throughput screening fluoroelastomer membranes cell culture paracellular/transcellular transport beating force microfabrication drug hepatotoxicity biomimetic oxidation compression microfluidics surfactant protein PDMS neuronal cell networks neuronal guidance trans-epithelial electrical resistance spheroid array organ-on-a-chip (OOC) biomechanics cell organ-on-chips organ-on-chip stretch shear stress shear flow image-based screening drug metabolism vascularization human induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM) stress barrier permeability bio-mechanical property cardiac 3D tissue endothelial cell activation organoid silicon lattice light-sheet microscopy integrated pump SH-SY5Y cells thrombolysis 3D cell culture neuronal cells drug efficacy vascularized tumor model thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology |
| url | 46127 |
| work_keys_str_mv | AT tungyichung organsonchips AT torisawayusuke organsonchips |