Plant Natural Products for Human Health
Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complemen...
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| Główni autorzy: | , |
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| Format: | Online |
| Język: | angielski |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | 32823 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
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| _version_ | 1869514846308925440 |
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| author | Zhang, Hongjie Che, Chun-Tao |
| author_browse | Che, Chun-Tao Zhang, Hongjie |
| author_facet | Zhang, Hongjie Che, Chun-Tao |
| author_sort | Zhang, Hongjie |
| collection | Directory of Open Access Books |
| description | Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs for human use, from morphine discovered in the early nineteenth century to the more recent paclitaxel and artemisinin. Today, we are witnessing a global resurgence in interest and use of plant-based therapies and botanical products, and natural products remain an important and viable source of lead compounds in many drug discovery programs.This Special Issue on “Plant Natural Products for Human Health” compiles a series of scientific reports to demonstrate the medicinal potentials of plant natural products. It covers a range of disease targets, such as diabetes, inflammation, cancer, neurological disease, cardiovascular disease, liver damage, bacterial, and fungus infection and malarial. These papers provide important insights into the current state of research on drug discovery and new techniques. It is hoped that this Special Issue will serve as a timely reference for researchers and scholars who are interested in the discovery of potentially useful molecules from plant sources for health-related applications. |
| format | Online |
| id | doab-20.500.12854ir-56345 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-563452024-03-30T23:21:40Z Plant Natural Products for Human Health Zhang, Hongjie Che, Chun-Tao R5-920 RM1-950 PhGs bitter orange immunomodulator A549 cells bergapten triptolide BMP/Smad phytochemicals antioxidant enzymes kumquat MTT assay HepaRG cells human health nanoparticles dendritic cells drug discovery biofilm catechin antitubercular activity Panax notoginseng saponins animals mouse-hair growth A? curcumin WNT/?-catenin copaiba AD Plasmodium parasites traditional medicine procyanidin A2 PET inhibition rheumatoid arthritis cannabinoid type 1 receptor iridoids inflammatory bowel disease acute liver injury human-hair-follicle dermal papilla cells Neuroprotective dihydromyricetin AMPK thromboembolism ginseng drug design and development endoplasmic reticulum stress mitogen-activated protein kinase Nrf2 prenylated flavonoids inflammation preclinical studies plants dietary supplements Glycyrrhiza uralensis aspirin Tripterygium wilfordii P. eryngii reperfusion ethnopharmacology glucans innovation hpatoprotection hinokitiol phytocannabinoid antistaphylococcal activity Shh/Gli green tea sesquiterpenoids adjuvant-induced arthritis yuzu hepatotoxicity p53/Bax Keap1 nuclear factor-kappaB oxidative stress pharmacokinetic study cinnamamides toxicity APAP Astragali Radix computational softwares plant natural product onion anti-malaria activity lipogenesis bleeding time diterpenoids Penthorum chinense Pursh myocardial hypertrophy automation adjuvant grapefruit melanoma cell essential oil sweet orange Amadori rearrangement compounds heme oxygenase global health calorie restriction bergamot liposomes EGCG celastrol herb–drug interactions cannabigerol anti-inflammation OH· free radical molecular targets gluconeogenesis microbiome SIRT1 fucoidan heart PC12 cells acetaminophen omics time-kill assay arthritis lychee seed bioinformatics structure–activity relationship precision medicine orange petitgrain immune modulation antiproliferation flavonoids scoulerine oleoresin triterpenic acids Cannabis sativa NAFLD biological activity differentiation oxygen consumption rate mitochondrial bioenergetics neroli apoptosis targeted delivery platelet activation protein kinase heat-process hepatic steatosis hyperglycemia natural products lemon genistein neuroinflammation astragaloside IV cytoxicity flavonoid paracetamol medicinal plants insulin resistance resveratrol mandarin garlic TGF-? morin hydrate sirtuin 3 MMPs gomisin N lime Ziziphus jujuba antifungal activity ischemia migration caspases small molecules thema EDItEUR::M Medicine and Nursing Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs for human use, from morphine discovered in the early nineteenth century to the more recent paclitaxel and artemisinin. Today, we are witnessing a global resurgence in interest and use of plant-based therapies and botanical products, and natural products remain an important and viable source of lead compounds in many drug discovery programs.This Special Issue on “Plant Natural Products for Human Health” compiles a series of scientific reports to demonstrate the medicinal potentials of plant natural products. It covers a range of disease targets, such as diabetes, inflammation, cancer, neurological disease, cardiovascular disease, liver damage, bacterial, and fungus infection and malarial. These papers provide important insights into the current state of research on drug discovery and new techniques. It is hoped that this Special Issue will serve as a timely reference for researchers and scholars who are interested in the discovery of potentially useful molecules from plant sources for health-related applications. 2021-02-11T23:04:05Z 2021-02-11T23:04:05Z 2019-04-05 10:34:31 2019 book 32823 9783038977124 https://directory.doabooks.org/handle/20.500.12854/56345 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://play.google.com/books/publish/a/14935057684283403269#details/ISBN:9783038977124 https://mdpi.com/books/pdfview/book/1178 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-713-1 10.3390/books978-3-03897-713-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038977124 514 open access |
| spellingShingle | R5-920 RM1-950 PhGs bitter orange immunomodulator A549 cells bergapten triptolide BMP/Smad phytochemicals antioxidant enzymes kumquat MTT assay HepaRG cells human health nanoparticles dendritic cells drug discovery biofilm catechin antitubercular activity Panax notoginseng saponins animals mouse-hair growth A? curcumin WNT/?-catenin copaiba AD Plasmodium parasites traditional medicine procyanidin A2 PET inhibition rheumatoid arthritis cannabinoid type 1 receptor iridoids inflammatory bowel disease acute liver injury human-hair-follicle dermal papilla cells Neuroprotective dihydromyricetin AMPK thromboembolism ginseng drug design and development endoplasmic reticulum stress mitogen-activated protein kinase Nrf2 prenylated flavonoids inflammation preclinical studies plants dietary supplements Glycyrrhiza uralensis aspirin Tripterygium wilfordii P. eryngii reperfusion ethnopharmacology glucans innovation hpatoprotection hinokitiol phytocannabinoid antistaphylococcal activity Shh/Gli green tea sesquiterpenoids adjuvant-induced arthritis yuzu hepatotoxicity p53/Bax Keap1 nuclear factor-kappaB oxidative stress pharmacokinetic study cinnamamides toxicity APAP Astragali Radix computational softwares plant natural product onion anti-malaria activity lipogenesis bleeding time diterpenoids Penthorum chinense Pursh myocardial hypertrophy automation adjuvant grapefruit melanoma cell essential oil sweet orange Amadori rearrangement compounds heme oxygenase global health calorie restriction bergamot liposomes EGCG celastrol herb–drug interactions cannabigerol anti-inflammation OH· free radical molecular targets gluconeogenesis microbiome SIRT1 fucoidan heart PC12 cells acetaminophen omics time-kill assay arthritis lychee seed bioinformatics structure–activity relationship precision medicine orange petitgrain immune modulation antiproliferation flavonoids scoulerine oleoresin triterpenic acids Cannabis sativa NAFLD biological activity differentiation oxygen consumption rate mitochondrial bioenergetics neroli apoptosis targeted delivery platelet activation protein kinase heat-process hepatic steatosis hyperglycemia natural products lemon genistein neuroinflammation astragaloside IV cytoxicity flavonoid paracetamol medicinal plants insulin resistance resveratrol mandarin garlic TGF-? morin hydrate sirtuin 3 MMPs gomisin N lime Ziziphus jujuba antifungal activity ischemia migration caspases small molecules thema EDItEUR::M Medicine and Nursing Zhang, Hongjie Che, Chun-Tao Plant Natural Products for Human Health |
| title | Plant Natural Products for Human Health |
| title_full | Plant Natural Products for Human Health |
| title_fullStr | Plant Natural Products for Human Health |
| title_full_unstemmed | Plant Natural Products for Human Health |
| title_short | Plant Natural Products for Human Health |
| title_sort | plant natural products for human health |
| topic | R5-920 RM1-950 PhGs bitter orange immunomodulator A549 cells bergapten triptolide BMP/Smad phytochemicals antioxidant enzymes kumquat MTT assay HepaRG cells human health nanoparticles dendritic cells drug discovery biofilm catechin antitubercular activity Panax notoginseng saponins animals mouse-hair growth A? curcumin WNT/?-catenin copaiba AD Plasmodium parasites traditional medicine procyanidin A2 PET inhibition rheumatoid arthritis cannabinoid type 1 receptor iridoids inflammatory bowel disease acute liver injury human-hair-follicle dermal papilla cells Neuroprotective dihydromyricetin AMPK thromboembolism ginseng drug design and development endoplasmic reticulum stress mitogen-activated protein kinase Nrf2 prenylated flavonoids inflammation preclinical studies plants dietary supplements Glycyrrhiza uralensis aspirin Tripterygium wilfordii P. eryngii reperfusion ethnopharmacology glucans innovation hpatoprotection hinokitiol phytocannabinoid antistaphylococcal activity Shh/Gli green tea sesquiterpenoids adjuvant-induced arthritis yuzu hepatotoxicity p53/Bax Keap1 nuclear factor-kappaB oxidative stress pharmacokinetic study cinnamamides toxicity APAP Astragali Radix computational softwares plant natural product onion anti-malaria activity lipogenesis bleeding time diterpenoids Penthorum chinense Pursh myocardial hypertrophy automation adjuvant grapefruit melanoma cell essential oil sweet orange Amadori rearrangement compounds heme oxygenase global health calorie restriction bergamot liposomes EGCG celastrol herb–drug interactions cannabigerol anti-inflammation OH· free radical molecular targets gluconeogenesis microbiome SIRT1 fucoidan heart PC12 cells acetaminophen omics time-kill assay arthritis lychee seed bioinformatics structure–activity relationship precision medicine orange petitgrain immune modulation antiproliferation flavonoids scoulerine oleoresin triterpenic acids Cannabis sativa NAFLD biological activity differentiation oxygen consumption rate mitochondrial bioenergetics neroli apoptosis targeted delivery platelet activation protein kinase heat-process hepatic steatosis hyperglycemia natural products lemon genistein neuroinflammation astragaloside IV cytoxicity flavonoid paracetamol medicinal plants insulin resistance resveratrol mandarin garlic TGF-? morin hydrate sirtuin 3 MMPs gomisin N lime Ziziphus jujuba antifungal activity ischemia migration caspases small molecules thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RM1-950 PhGs bitter orange immunomodulator A549 cells bergapten triptolide BMP/Smad phytochemicals antioxidant enzymes kumquat MTT assay HepaRG cells human health nanoparticles dendritic cells drug discovery biofilm catechin antitubercular activity Panax notoginseng saponins animals mouse-hair growth A? curcumin WNT/?-catenin copaiba AD Plasmodium parasites traditional medicine procyanidin A2 PET inhibition rheumatoid arthritis cannabinoid type 1 receptor iridoids inflammatory bowel disease acute liver injury human-hair-follicle dermal papilla cells Neuroprotective dihydromyricetin AMPK thromboembolism ginseng drug design and development endoplasmic reticulum stress mitogen-activated protein kinase Nrf2 prenylated flavonoids inflammation preclinical studies plants dietary supplements Glycyrrhiza uralensis aspirin Tripterygium wilfordii P. eryngii reperfusion ethnopharmacology glucans innovation hpatoprotection hinokitiol phytocannabinoid antistaphylococcal activity Shh/Gli green tea sesquiterpenoids adjuvant-induced arthritis yuzu hepatotoxicity p53/Bax Keap1 nuclear factor-kappaB oxidative stress pharmacokinetic study cinnamamides toxicity APAP Astragali Radix computational softwares plant natural product onion anti-malaria activity lipogenesis bleeding time diterpenoids Penthorum chinense Pursh myocardial hypertrophy automation adjuvant grapefruit melanoma cell essential oil sweet orange Amadori rearrangement compounds heme oxygenase global health calorie restriction bergamot liposomes EGCG celastrol herb–drug interactions cannabigerol anti-inflammation OH· free radical molecular targets gluconeogenesis microbiome SIRT1 fucoidan heart PC12 cells acetaminophen omics time-kill assay arthritis lychee seed bioinformatics structure–activity relationship precision medicine orange petitgrain immune modulation antiproliferation flavonoids scoulerine oleoresin triterpenic acids Cannabis sativa NAFLD biological activity differentiation oxygen consumption rate mitochondrial bioenergetics neroli apoptosis targeted delivery platelet activation protein kinase heat-process hepatic steatosis hyperglycemia natural products lemon genistein neuroinflammation astragaloside IV cytoxicity flavonoid paracetamol medicinal plants insulin resistance resveratrol mandarin garlic TGF-? morin hydrate sirtuin 3 MMPs gomisin N lime Ziziphus jujuba antifungal activity ischemia migration caspases small molecules thema EDItEUR::M Medicine and Nursing |
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