Recent Advances in the Study of the Host-Fungus Interaction
Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is...
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| フォーマット: | Online |
| 言語: | 英語 |
| 出版事項: |
Frontiers Media SA
2021
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| 主題: | |
| オンライン･アクセス: | 22914 |
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| _version_ | 1869525709843595264 |
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| author | Attila Gacser Hector M. Mora-Montes |
| author_browse | Attila Gacser Hector M. Mora-Montes |
| author_facet | Attila Gacser Hector M. Mora-Montes |
| author_sort | Attila Gacser |
| collection | Directory of Open Access Books |
| description | Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response. |
| format | Online |
| id | doab-20.500.12854ir-57752 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-577522024-04-05T17:31:04Z Recent Advances in the Study of the Host-Fungus Interaction Attila Gacser Hector M. Mora-Montes QR1-502 Q1-390 Candida albicans Cell Wall Aspergillus Histoplasma melanin Paraccocidioides Cryptococcus Dermatophytes host-fungus interaction Candida parapsilosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response. 2021-02-12T01:05:14Z 2021-02-12T01:05:14Z 2017-07-06 13:27:36 2017 book 22914 16648714 9782889450626 https://directory.doabooks.org/handle/20.500.12854/57752 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Recent_Advances_in_the_Study_of_the_Host-Fungus_Interaction/1091#nogo http://journal.frontiersin.org/researchtopic/3617/recent-advances-in-the-study-of-the-host-fungus-interaction Frontiers Media SA 10.3389/978-2-88945-062-6 10.3389/978-2-88945-062-6 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889450626 148 open access |
| spellingShingle | QR1-502 Q1-390 Candida albicans Cell Wall Aspergillus Histoplasma melanin Paraccocidioides Cryptococcus Dermatophytes host-fungus interaction Candida parapsilosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) Attila Gacser Hector M. Mora-Montes Recent Advances in the Study of the Host-Fungus Interaction |
| title | Recent Advances in the Study of the Host-Fungus Interaction |
| title_full | Recent Advances in the Study of the Host-Fungus Interaction |
| title_fullStr | Recent Advances in the Study of the Host-Fungus Interaction |
| title_full_unstemmed | Recent Advances in the Study of the Host-Fungus Interaction |
| title_short | Recent Advances in the Study of the Host-Fungus Interaction |
| title_sort | recent advances in the study of the host fungus interaction |
| topic | QR1-502 Q1-390 Candida albicans Cell Wall Aspergillus Histoplasma melanin Paraccocidioides Cryptococcus Dermatophytes host-fungus interaction Candida parapsilosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| topic_facet | QR1-502 Q1-390 Candida albicans Cell Wall Aspergillus Histoplasma melanin Paraccocidioides Cryptococcus Dermatophytes host-fungus interaction Candida parapsilosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| url | 22914 |
| work_keys_str_mv | AT attilagacser recentadvancesinthestudyofthehostfungusinteraction AT hectormmoramontes recentadvancesinthestudyofthehostfungusinteraction |