Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease

The role of ROS/RNS signaling in cardiovascular functions and diseases is increasingly emerging in the last decades. The involvement of ROS/RNS in the control of a large number of cardiovascular functions like the regulation of the vascular tone, the control of blood pressure or myocyte excitation-c...

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Principais autores: Pasquale Pagliaro, Mariarosaria Santillo
Formato: Online
Idioma:inglês
Publicado em: Frontiers Media SA 2021
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Acesso em linha:32087
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author Pasquale Pagliaro
Mariarosaria Santillo
author_browse Mariarosaria Santillo
Pasquale Pagliaro
author_facet Pasquale Pagliaro
Mariarosaria Santillo
author_sort Pasquale Pagliaro
collection Directory of Open Access Books
description The role of ROS/RNS signaling in cardiovascular functions and diseases is increasingly emerging in the last decades. The involvement of ROS/RNS in the control of a large number of cardiovascular functions like the regulation of the vascular tone, the control of blood pressure or myocyte excitation-contraction coupling and force development has been broadly investigated and in part clarified. On the other hand, many efforts have been focused in clarifying the redox mechanisms involved in cardiovascular diseases like ischemia/reperfusion injury, diabetes-associated cardiovascular dysfunctions, atherosclerosis or hypertension, just to mention the major ones. However, in most cases the two levels of investigation remain separate and not interlaced, failing in the attempt to provide a unified vision of the pathophysiologic mechanisms of cardiovascular diseases. The major aim of the Research Topic has been to collect original papers and review articles dealing with the issue from basic to translation research point of views. The topic includes contributions that highlight different interesting aspects of cardiovascular biology with an integrated approach useful for the development of new ideas and advancements in the field of redox signaling in the control of normal cardiovascular functions and their disruption in diseases.
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spelling doab-20.500.12854ir-579162024-03-31T22:45:05Z Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease Pasquale Pagliaro Mariarosaria Santillo QP1-981 Q1-390 Antioxidants Metabolomics Stroke Exercise ischemia/reperfusion injury mitochondria and chaperones Pulmonary hypertention reactive oxygen and nitrogen species cardiac preconditioning and postconditioning Endothelium thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology The role of ROS/RNS signaling in cardiovascular functions and diseases is increasingly emerging in the last decades. The involvement of ROS/RNS in the control of a large number of cardiovascular functions like the regulation of the vascular tone, the control of blood pressure or myocyte excitation-contraction coupling and force development has been broadly investigated and in part clarified. On the other hand, many efforts have been focused in clarifying the redox mechanisms involved in cardiovascular diseases like ischemia/reperfusion injury, diabetes-associated cardiovascular dysfunctions, atherosclerosis or hypertension, just to mention the major ones. However, in most cases the two levels of investigation remain separate and not interlaced, failing in the attempt to provide a unified vision of the pathophysiologic mechanisms of cardiovascular diseases. The major aim of the Research Topic has been to collect original papers and review articles dealing with the issue from basic to translation research point of views. The topic includes contributions that highlight different interesting aspects of cardiovascular biology with an integrated approach useful for the development of new ideas and advancements in the field of redox signaling in the control of normal cardiovascular functions and their disruption in diseases. 2021-02-12T01:19:34Z 2021-02-12T01:19:34Z 2019-01-23 14:53:43 2019 book 32087 16648714 9782889457267 https://directory.doabooks.org/handle/20.500.12854/57916 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/5855/redox-and-nitrosative-signaling-in-cardiovascular-system-from-physiological-response-to-disease Frontiers Media SA 10.3389/978-2-88945-726-7 10.3389/978-2-88945-726-7 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889457267 258 open access
spellingShingle QP1-981
Q1-390
Antioxidants
Metabolomics
Stroke
Exercise
ischemia/reperfusion injury
mitochondria and chaperones
Pulmonary hypertention
reactive oxygen and nitrogen species
cardiac preconditioning and postconditioning
Endothelium
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
Pasquale Pagliaro
Mariarosaria Santillo
Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease
title Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease
title_full Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease
title_fullStr Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease
title_full_unstemmed Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease
title_short Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease
title_sort redox and nitrosative signaling in cardiovascular system from physiological response to disease
topic QP1-981
Q1-390
Antioxidants
Metabolomics
Stroke
Exercise
ischemia/reperfusion injury
mitochondria and chaperones
Pulmonary hypertention
reactive oxygen and nitrogen species
cardiac preconditioning and postconditioning
Endothelium
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
topic_facet QP1-981
Q1-390
Antioxidants
Metabolomics
Stroke
Exercise
ischemia/reperfusion injury
mitochondria and chaperones
Pulmonary hypertention
reactive oxygen and nitrogen species
cardiac preconditioning and postconditioning
Endothelium
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
url 32087
work_keys_str_mv AT pasqualepagliaro redoxandnitrosativesignalingincardiovascularsystemfromphysiologicalresponsetodisease
AT mariarosariasantillo redoxandnitrosativesignalingincardiovascularsystemfromphysiologicalresponsetodisease