Regulation by non-coding RNAs

Regulatory non-protein-coding RNA genes and their transcripts were first found and characterized in bacteria but encompass all biological kingdoms. The complexity of non-coding RNAs (ncRNAs) in terms of number and types increases with degree of biological development, whereby humans and other primat...

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Cyhoeddwyd: MDPI - Multidisciplinary Digital Publishing Institute 2021
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Mynediad Ar-lein:16619
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collection Directory of Open Access Books
description Regulatory non-protein-coding RNA genes and their transcripts were first found and characterized in bacteria but encompass all biological kingdoms. The complexity of non-coding RNAs (ncRNAs) in terms of number and types increases with degree of biological development, whereby humans and other primates appear to have the largest number. Many regulatory ncRNAs base-pair to a target RNA or DNA and inhibit target function. Bacterial ncRNA genes largely respond to environmental stress conditions and help protect the organism from adverse conditions. The prokaryotic RNAs are for the most part small (<200 bp) and are commonly referred to as small regulatory RNAs (sRNAs). Eukaryotic RNAs consist of small <200 nt RNAs and large >200 nt (termed lncRNAs). The eukaryotic small RNAs include miRNAs, siRNAs, and piRNAs. miRNAs inhibit mRNA functions and may also be associated with cancer. lncRNAs functions are multifaceted and include epigenetic regulation and animal development. The bacterial and archeal immune system CRISPR, and the eukaryotic piwi-interacting RNAs (piRNA) immune system that inhibits mobile elements in germ line cells both function by via RNA transcript/ target DNA heteroduplex base-pairing are a specific class of RNAs that protect cells from invading transposons/and or viruses. siRNAs function in plant and invertebrate immune systems and protect against viral infections. [...]
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institution Directory of Open Access Books
language eng
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-580332022-01-31T11:55:08Z Regulation by non-coding RNAs lncRNA CRISPR RNA sRNA piRNA regulatory small RNA fragments miRNA siRNA ncRNA Regulatory RNA Regulatory non-protein-coding RNA genes and their transcripts were first found and characterized in bacteria but encompass all biological kingdoms. The complexity of non-coding RNAs (ncRNAs) in terms of number and types increases with degree of biological development, whereby humans and other primates appear to have the largest number. Many regulatory ncRNAs base-pair to a target RNA or DNA and inhibit target function. Bacterial ncRNA genes largely respond to environmental stress conditions and help protect the organism from adverse conditions. The prokaryotic RNAs are for the most part small (<200 bp) and are commonly referred to as small regulatory RNAs (sRNAs). Eukaryotic RNAs consist of small <200 nt RNAs and large >200 nt (termed lncRNAs). The eukaryotic small RNAs include miRNAs, siRNAs, and piRNAs. miRNAs inhibit mRNA functions and may also be associated with cancer. lncRNAs functions are multifaceted and include epigenetic regulation and animal development. The bacterial and archeal immune system CRISPR, and the eukaryotic piwi-interacting RNAs (piRNA) immune system that inhibits mobile elements in germ line cells both function by via RNA transcript/ target DNA heteroduplex base-pairing are a specific class of RNAs that protect cells from invading transposons/and or viruses. siRNAs function in plant and invertebrate immune systems and protect against viral infections. [...] 2021-02-12T01:30:28Z 2021-02-12T01:30:28Z 2015-01-12 11:06:27 2014 book 16619 9783038420118 9783038420064 https://directory.doabooks.org/handle/20.500.12854/58033 eng application/octet-stream Attribution 4.0 International http://www.amazon.com/dp/3038420069 https://www.mdpi.com/books/pdfview/book/35 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038420118 9783038420064 244 open access
spellingShingle lncRNA
CRISPR RNA
sRNA
piRNA
regulatory small RNA fragments
miRNA
siRNA
ncRNA
Regulatory RNA
Regulation by non-coding RNAs
title Regulation by non-coding RNAs
title_full Regulation by non-coding RNAs
title_fullStr Regulation by non-coding RNAs
title_full_unstemmed Regulation by non-coding RNAs
title_short Regulation by non-coding RNAs
title_sort regulation by non coding rnas
topic lncRNA
CRISPR RNA
sRNA
piRNA
regulatory small RNA fragments
miRNA
siRNA
ncRNA
Regulatory RNA
topic_facet lncRNA
CRISPR RNA
sRNA
piRNA
regulatory small RNA fragments
miRNA
siRNA
ncRNA
Regulatory RNA
url 16619