Repetitive Structures in Biological Sequences: Algorithms and Applications
Repetitive structures in biological sequences are emerging as an active focus of research and the unifying concept of "repeatome" (the ensemble of knowledge associated with repeating structures in genomic/proteomic sequences) has been recently proposed in order to highlight several converging trends...
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| פורמט: | Online |
| שפה: | אנגלית |
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Frontiers Media SA
2021
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| נושאים: | |
| גישה מקוונת: | 25539 |
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| _version_ | 1869518646348349440 |
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| author | Marco Pellegrini Alberto Magi Costas S. Iliopoulos |
| author_browse | Alberto Magi Costas S. Iliopoulos Marco Pellegrini |
| author_facet | Marco Pellegrini Alberto Magi Costas S. Iliopoulos |
| author_sort | Marco Pellegrini |
| collection | Directory of Open Access Books |
| description | Repetitive structures in biological sequences are emerging as an active focus of research and the unifying concept of "repeatome" (the ensemble of knowledge associated with repeating structures in genomic/proteomic sequences) has been recently proposed in order to highlight several converging trends. One main trend is the ongoing discovery that genomic repetitions are linked to many biological significant events and functions. Diseases (e.g. Huntington's disease) have been causally linked with abnormal expansion of certain repeating sequences in the human genome. Deletions or multiple copy duplications of genes (Copy Number Variations) are important in the aetiology of cancer, Alzheimer, and Parkinson diseases. A second converging trend has been the emergence of many different models and algorithms for detecting non-obvious repeating patterns in strings with applications to in genomic data. Borrowing methodologies from combinatorial pattern, matching, string algorithms, data structures, data mining and machine learning these new approaches break the limitations of the current approaches and offer a new way to design better trans-disciplinary research. The articles collected in this book provides a glance into the rich emerging area of repeatome research, addressing some of its pressing challenges. We believe that these contributions are valuable resources for repeatome research and will stimulate further research from bioinformatic, statistical, and biological points of view. |
| format | Online |
| id | doab-20.500.12854ir-58232 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-582322024-04-11T15:11:33Z Repetitive Structures in Biological Sequences: Algorithms and Applications Marco Pellegrini Alberto Magi Costas S. Iliopoulos TA1-2040 TP248.13-248.65 Algorithms Repetitive structures next generation sequencing tandem repeats transposable elements thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology Repetitive structures in biological sequences are emerging as an active focus of research and the unifying concept of "repeatome" (the ensemble of knowledge associated with repeating structures in genomic/proteomic sequences) has been recently proposed in order to highlight several converging trends. One main trend is the ongoing discovery that genomic repetitions are linked to many biological significant events and functions. Diseases (e.g. Huntington's disease) have been causally linked with abnormal expansion of certain repeating sequences in the human genome. Deletions or multiple copy duplications of genes (Copy Number Variations) are important in the aetiology of cancer, Alzheimer, and Parkinson diseases. A second converging trend has been the emergence of many different models and algorithms for detecting non-obvious repeating patterns in strings with applications to in genomic data. Borrowing methodologies from combinatorial pattern, matching, string algorithms, data structures, data mining and machine learning these new approaches break the limitations of the current approaches and offer a new way to design better trans-disciplinary research. The articles collected in this book provides a glance into the rich emerging area of repeatome research, addressing some of its pressing challenges. We believe that these contributions are valuable resources for repeatome research and will stimulate further research from bioinformatic, statistical, and biological points of view. 2021-02-12T01:52:49Z 2021-02-12T01:52:49Z 2018-02-27 16:16:44 2016 book 25539 16648714 9782889450183 https://directory.doabooks.org/handle/20.500.12854/58232 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Repetitive_Structures_in_Biological_Sequences_Algorithms_and_Applications/1040#nogo http://journal.frontiersin.org/researchtopic/2548/repetitive-structures-in-biological-sequences-algorithms-and-applications Frontiers Media SA 10.3389/978-2-88945-018-3 10.3389/978-2-88945-018-3 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889450183 93 open access |
| spellingShingle | TA1-2040 TP248.13-248.65 Algorithms Repetitive structures next generation sequencing tandem repeats transposable elements thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology Marco Pellegrini Alberto Magi Costas S. Iliopoulos Repetitive Structures in Biological Sequences: Algorithms and Applications |
| title | Repetitive Structures in Biological Sequences: Algorithms and Applications |
| title_full | Repetitive Structures in Biological Sequences: Algorithms and Applications |
| title_fullStr | Repetitive Structures in Biological Sequences: Algorithms and Applications |
| title_full_unstemmed | Repetitive Structures in Biological Sequences: Algorithms and Applications |
| title_short | Repetitive Structures in Biological Sequences: Algorithms and Applications |
| title_sort | repetitive structures in biological sequences algorithms and applications |
| topic | TA1-2040 TP248.13-248.65 Algorithms Repetitive structures next generation sequencing tandem repeats transposable elements thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology |
| topic_facet | TA1-2040 TP248.13-248.65 Algorithms Repetitive structures next generation sequencing tandem repeats transposable elements thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology |
| url | 25539 |
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