Role of lipids in virus assembly
RNA enveloped viruses comprise several families belonging to plus and minus strand RNA viruses, such as retroviruses, flavoviruses and orthomyxoviruses. Viruses utilize cellular lipids during critical steps of replication like entry, assembly and egress. Growing evidence indicate important roles for...
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| Format: | Online |
| Language: | English |
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Frontiers Media SA
2021
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| Online Access: | 18693 |
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| _version_ | 1869523810050375680 |
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| author | Jamil S Saad Delphine M. Muriaux |
| author_browse | Delphine M. Muriaux Jamil S Saad |
| author_facet | Jamil S Saad Delphine M. Muriaux |
| author_sort | Jamil S Saad |
| collection | Directory of Open Access Books |
| description | RNA enveloped viruses comprise several families belonging to plus and minus strand RNA viruses, such as retroviruses, flavoviruses and orthomyxoviruses. Viruses utilize cellular lipids during critical steps of replication like entry, assembly and egress. Growing evidence indicate important roles for lipids and lipid nanodomains in virus assembly. This special topic covers key aspects of virus-membrane interactions during assembly and egress, especially those of retroviruses and Ebola virus (EBOV). Virus assembly and release involve specific and nonspecific interactions between viral proteins and membrane compartments. Retroviral Gag proteins assemble predominantly on the PM. Despite the great progress in identifying the factors that modulate retroviral Gag assembly on the PM, there are still gaps in our understanding of precise mechanisms of Gag-membrane interactions. Studies over the last two decades have focused on the mechanisms by which other retroviral Gag proteins interact with membranes during assembly. These include human immunodeficiency virus (HIV), Rous sarcoma virus (RSV), equine infectious anemia virus (EIAV), Mason-Pfizer monkey virus (M-PMV), murine leukemia virus (MLV), and human T-lymphotropic virus type (HTLV-1). Additionally, assembly of filoviruses such as EBOV also occurs on the inner leaflet of the PM. The articles published under this special topic highlight the latest understanding of the role of membrane lipids during virus assembly, egress and release. |
| format | Online |
| id | doab-20.500.12854ir-58588 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-585882024-04-05T17:31:03Z Role of lipids in virus assembly Jamil S Saad Delphine M. Muriaux QR1-502 QK1-989 Q1-390 NMR Matrix membrane Gag Ebola VP40 retroviruses HIV 1 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) RNA enveloped viruses comprise several families belonging to plus and minus strand RNA viruses, such as retroviruses, flavoviruses and orthomyxoviruses. Viruses utilize cellular lipids during critical steps of replication like entry, assembly and egress. Growing evidence indicate important roles for lipids and lipid nanodomains in virus assembly. This special topic covers key aspects of virus-membrane interactions during assembly and egress, especially those of retroviruses and Ebola virus (EBOV). Virus assembly and release involve specific and nonspecific interactions between viral proteins and membrane compartments. Retroviral Gag proteins assemble predominantly on the PM. Despite the great progress in identifying the factors that modulate retroviral Gag assembly on the PM, there are still gaps in our understanding of precise mechanisms of Gag-membrane interactions. Studies over the last two decades have focused on the mechanisms by which other retroviral Gag proteins interact with membranes during assembly. These include human immunodeficiency virus (HIV), Rous sarcoma virus (RSV), equine infectious anemia virus (EIAV), Mason-Pfizer monkey virus (M-PMV), murine leukemia virus (MLV), and human T-lymphotropic virus type (HTLV-1). Additionally, assembly of filoviruses such as EBOV also occurs on the inner leaflet of the PM. The articles published under this special topic highlight the latest understanding of the role of membrane lipids during virus assembly, egress and release. 2021-02-12T02:27:59Z 2021-02-12T02:27:59Z 2016-03-10 08:14:32 2015 book 18693 16648714 9782889195824 https://directory.doabooks.org/handle/20.500.12854/58588 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Role_of_Lipids_in_Virus_Assembly/657 http://journal.frontiersin.org/researchtopic/1576/role-of-lipids-in-virus-assembly Frontiers Media SA 10.3389/978-2-88919-582-4 10.3389/978-2-88919-582-4 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889195824 91 open access |
| spellingShingle | QR1-502 QK1-989 Q1-390 NMR Matrix membrane Gag Ebola VP40 retroviruses HIV 1 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) Jamil S Saad Delphine M. Muriaux Role of lipids in virus assembly |
| title | Role of lipids in virus assembly |
| title_full | Role of lipids in virus assembly |
| title_fullStr | Role of lipids in virus assembly |
| title_full_unstemmed | Role of lipids in virus assembly |
| title_short | Role of lipids in virus assembly |
| title_sort | role of lipids in virus assembly |
| topic | QR1-502 QK1-989 Q1-390 NMR Matrix membrane Gag Ebola VP40 retroviruses HIV 1 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| topic_facet | QR1-502 QK1-989 Q1-390 NMR Matrix membrane Gag Ebola VP40 retroviruses HIV 1 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| url | 18693 |
| work_keys_str_mv | AT jamilssaad roleoflipidsinvirusassembly AT delphinemmuriaux roleoflipidsinvirusassembly |