The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, devastating and fatal disease characterized by selective loss of upper and lower motor neurons of the cerebral cortex, brainstem, spinal cord and muscle atrophy. In spite of many years of research, the pathogenesis of ALS is still not wel...

Ausführliche Beschreibung

Bibliographische Detailangaben

1. Verfasser:	Manoj Kumar Jaiswal
Format:	Online
Sprache:	Englisch
Veröffentlicht:	Frontiers Media SA 2021
Schlagworte:	RC321-571 Q1-390 Mitochondria neurodegenerative disease Ca2+ signaling multidrug therapy Amyotrophic lateral sclerosis (ALS) Superoxide dismutase 1 (SOD1) Motor neuron disease (MND) excitotoxicity Riluzole multifactorial disease thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Online-Zugang:	22997
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!