Second hand smoke and COPD: lessons from animal studies

Cigarette smoke exposure is the key initiator of chronic inflammation, alveolar destruction, and the loss of alveolar blood vessels that lead to the development of chronic obstructive pulmonary disease (COPD) which is comprised of emphysema and chronic bronchitis. Exposure to secondhand smoke (SHS)...

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Những tác giả chính: Laima Taraseviciene-Stewart, Adelheid Kratzer, Michael Borchers
Định dạng: Online
Ngôn ngữ:Tiếng Anh
Được phát hành: Frontiers Media SA 2021
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Truy cập trực tuyến:18578
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author Laima Taraseviciene-Stewart
Adelheid Kratzer
Michael Borchers
author_browse Adelheid Kratzer
Laima Taraseviciene-Stewart
Michael Borchers
author_facet Laima Taraseviciene-Stewart
Adelheid Kratzer
Michael Borchers
author_sort Laima Taraseviciene-Stewart
collection Directory of Open Access Books
description Cigarette smoke exposure is the key initiator of chronic inflammation, alveolar destruction, and the loss of alveolar blood vessels that lead to the development of chronic obstructive pulmonary disease (COPD) which is comprised of emphysema and chronic bronchitis. Exposure to secondhand smoke (SHS) is the major risk factor for non-smokers to develop emphysema. While the first-hand smoke is directly inhaled by smokers, passive smoking occurs when non-smokers are involuntary exposed to environmental tobacco smoke also known as second hand smoke (SHS). SHS is a mixture of 2 forms of smoke that come from burning tobacco: side stream smoke (smoke that comes from the end of a lit cigarette, pipe, or cigar) and mainstream smoke (smoke that is exhaled by a smoker). These two types of smoke have basically the same composition, however in SHS many toxic components are more concentrated than in first-hand smoke, therefore more hazardous for people’s health. Several pathological events have been implicated in the development of SHS-induced COPD, but many aspects of this pathology remain poorly understood halting the development of new advanced treatments for this detrimental disease. In this respect we have welcomed leading investigators in the field to share their research findings and provide their thoughts regarding the mechanisms of the SHS exposure-induced immune responses and inflammatory mechanisms of lung destruction in SHS-induced COPD and related comorbidities.
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spelling doab-20.500.12854ir-590752024-03-31T22:45:10Z Second hand smoke and COPD: lessons from animal studies Laima Taraseviciene-Stewart Adelheid Kratzer Michael Borchers QP1-981 Q1-390 Autoantibodies Cytokines pulmonary hypertension pulmonary injections Inflammation matrix degradation Immune responses Macrophages Cell signaling Monocytes and lymphocytes second hand smoke Heart Failure Emphysema thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology Cigarette smoke exposure is the key initiator of chronic inflammation, alveolar destruction, and the loss of alveolar blood vessels that lead to the development of chronic obstructive pulmonary disease (COPD) which is comprised of emphysema and chronic bronchitis. Exposure to secondhand smoke (SHS) is the major risk factor for non-smokers to develop emphysema. While the first-hand smoke is directly inhaled by smokers, passive smoking occurs when non-smokers are involuntary exposed to environmental tobacco smoke also known as second hand smoke (SHS). SHS is a mixture of 2 forms of smoke that come from burning tobacco: side stream smoke (smoke that comes from the end of a lit cigarette, pipe, or cigar) and mainstream smoke (smoke that is exhaled by a smoker). These two types of smoke have basically the same composition, however in SHS many toxic components are more concentrated than in first-hand smoke, therefore more hazardous for people’s health. Several pathological events have been implicated in the development of SHS-induced COPD, but many aspects of this pathology remain poorly understood halting the development of new advanced treatments for this detrimental disease. In this respect we have welcomed leading investigators in the field to share their research findings and provide their thoughts regarding the mechanisms of the SHS exposure-induced immune responses and inflammatory mechanisms of lung destruction in SHS-induced COPD and related comorbidities. 2021-02-12T03:09:53Z 2021-02-12T03:09:53Z 2016-02-05 17:24:33 2015 book 18578 16648714 9782889193165 https://directory.doabooks.org/handle/20.500.12854/59075 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Second_hand_smoke_and_COPD_lessons_from_animal_studies/517#nogo http://journal.frontiersin.org/researchtopic/710/second-hand-smoke-and-copd-lessons-from-animal-studies Frontiers Media SA 10.3389/978-2-88919-316-5 10.3389/978-2-88919-316-5 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193165 91 open access
spellingShingle QP1-981
Q1-390
Autoantibodies
Cytokines
pulmonary hypertension
pulmonary injections
Inflammation
matrix degradation
Immune responses
Macrophages
Cell signaling
Monocytes and lymphocytes
second hand smoke
Heart Failure
Emphysema
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
Laima Taraseviciene-Stewart
Adelheid Kratzer
Michael Borchers
Second hand smoke and COPD: lessons from animal studies
title Second hand smoke and COPD: lessons from animal studies
title_full Second hand smoke and COPD: lessons from animal studies
title_fullStr Second hand smoke and COPD: lessons from animal studies
title_full_unstemmed Second hand smoke and COPD: lessons from animal studies
title_short Second hand smoke and COPD: lessons from animal studies
title_sort second hand smoke and copd lessons from animal studies
topic QP1-981
Q1-390
Autoantibodies
Cytokines
pulmonary hypertension
pulmonary injections
Inflammation
matrix degradation
Immune responses
Macrophages
Cell signaling
Monocytes and lymphocytes
second hand smoke
Heart Failure
Emphysema
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
topic_facet QP1-981
Q1-390
Autoantibodies
Cytokines
pulmonary hypertension
pulmonary injections
Inflammation
matrix degradation
Immune responses
Macrophages
Cell signaling
Monocytes and lymphocytes
second hand smoke
Heart Failure
Emphysema
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
url 18578
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